This is article number 29.
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8/18/2003

Does your teenager break the rules and reject authority? Maybe it’s his brain.

http://abcnews.go.com/sections/living/MedicineCuttingEdge/brain030818_teenage.html

By John McKenzie
ABC NEWS

ABC reports about a brain imaging study using MRI that tracks the brains of normal children. This study provides physical evidence about the biological development of the normal brain and the individual pace of normal development.

What’s new, according Dr. Dr. Jay Giedd, of the National Institute of Mental Health “is that the brain’s anatomy in the teen years is changing far more dynamically than we would ever have guessed.”

The MRIs demonstrate that contrary to what neuropsychiatrists had assumed, the brain of teenagers is NOT completely developed. In fact, the most important distinctively human part of the brain is not developed in teenagers: “The images show one of the last parts of the brain to complete this maturation process is the prefrontal cortex, the part of the brain responsible for planning, judgment and self-control.”

This important study finally provides hard evidence to refute the absurd claim by the drug industry, and the psychiatric establishment— as set forth in the 2001 U.S. Surgeon General’s Report: 1 in 10 children and adolescents in America has a disabling mental disorder requiring treatment.

Physical evidence of normal differences in brain maturation is compelling: the evidence undermines current practice by pulling the rug out from under those who are “diagnosing” (and labeling) children as having “mental disorders” such as ADHD, “oppositional defiance disorder,” “mood swings” “generalized anxiety disorder”—as these disorders are diagnosed in children who lack self-control, lack mature attention spans, and are given to emotional swings. These and other signs of immaturity are normal. Maturity is arrived at individually, not according to someone’s charts or schedules.

The MRIs in this study provide hard evidence AGAINST current practice of prescribing psychotropic drugs for children and adolescents for behavioral problems because the drugs interfere with normal brain development.

The American Psychiatric Association and public health officials had better reconsider the consequences of their prescribing practices. Psychotropic drugs—including stimulants antidepressants (SSRIs) and antipsychotics alter normal functioning of neuroreceptors, brain size, and brain structure. The brain’s adaptation to the invasive action of psychotropic drugs may permanently interfere with normal brain function.

See a definitive article by the former director of NIMH, Dr. Steven Hyman, and Nestler, EJ. “Initiation and Adaptation: a Paradigm for Understanding Psychoactive Drug Action” in the American Journal of Psychiatry, 153:151-162.

Mental health professionals have been prescribing psychotropic drugs for children on the basis of erroneous assumptions about what constitutes “normal” and “abnormal” behavior in children. Scientific evidence suggests that children and teens who are prescribed these mind altering drugs are at risk because these drugs action may prevent them from EVER developing self-control and good judgment.

“The more teachers and the more parents [sic] understand that there is a biological limitation to the child’s ability to control and regulate emotion, [the more] they might be able to back off a little and be a bit more understanding.” The same should be said about child psychiatrists and the mental health industry.

ALLIANCE FOR HUMAN RESEARCH PROTECTION
(AHRP) http://www.ahrp.org
Contact: Vera Hassner Sharav
Tel: 212-595-8974
e-mail: veracare@ahrp.org

It’s the hope of just about every exasperated parent — to one day understand the adolescent brain. Now some scientists are doing cutting-edge research that may bring that day closer.

In charting the brain’s normal development through adolescence, scientists discovered the brain’s anatomy apparently keep on evolving far more than ever thought, which may help explain why can teens act the way they do.

Teenager Bryan Wright is one of hundreds of volunteers taking part in the research at the Child Psychiatry Branch of the National Institute of Mental Health in Bethesda, Md.

On summer evenings, Wright, 17, allows government researchers to peer into the very deepest recesses of his brain, just as they’ve been doing since he was 13.

Using magnetic resonance imaging, or MRI, government researchers can now journey through the brain, from top to bottom, left to right, back to front, and most important, from year to year.

“Recent advances in imaging technology, even over the last 18 months to two years, allow us to really zero in on specific brain parts,” said Dr. Jay Giedd, who directs the project as chief of brain imaging at the research center.

Giedd, like most of his colleagues, had thought that since the brain has reached 90 percent of its full size by the age of 6, that it was virtually fully developed. Not so.

“What’s new is that the brain’s anatomy in the teen years is changing far more dynamically than we would ever have guessed,” said Giedd.

In other words, the “makeup” of the brain, the individual elements of the brain, continue to evolve and become more efficient throughout the teenage years, even into a person’s 20s.

New Findings Explain Mood Swings

Giedd’s images show a thickening in gray matter on the outer part of the brain peaks at age 11 in girls and at age 12 in boys. Then, during the teen years, the brain trims back excess cells and connections so what’s left is more efficient.

The cells and connections used the most survive and flourish, and those not used will whither and die, said Giedd.

The images show one of the last parts of the brain to complete this maturation process is the prefrontal cortex, the part of the brain responsible for planning, judgment and self-control.

“[Adolescents] are capable of very strong emotions and very strong passions, but their prefrontal cortex hasn’t caught up with them yet. It’s as though they don’t have the brakes that allow them to slow those emotions down,” said Charles Nelson, a child psychologist at the University of Minnesota.

Researchers say this may help explain the often irrational behavior of teenagers: the mood swings, and the risks they’re often too willing to take.

And psychologists believe this new understanding of the adolescent brain — and its limitations — can help parents recognize there are some behaviors teenagers cannot easily control.

“If I walk into a class of kids who are 14 or 15,” said Nelson, “those kids have a level of brain maturity that just does not map onto the kinds of emotional decision-making that a lot of those kids are being asked to make by teachers and parents.”

Added Nelson: “The more teachers and the more parents that understand that there is a biological limitation to the child’s ability to control and regulate emotion, [the more] they might be able to back off a little and be a bit more understanding.