6/3/2000 – Prozac-induced death of child via impaired liver function

Finally reports are being made of deaths of children due to the toxicity
associated with Prozac. Below is an abstract on the death of a child due to
Prozac (fluoxetine). If you have not read my article entitled “The Next
Generation of Medical Guinea Pigs – Our Prozac, Zoloft and Paxil Babies” be
sure to do so. It is on our website and was published in the summer of 1998
and warns of the deadly effects of this liver enzyme system and children on
the SSRIs.

Ann Blake-Tracy, Executive Director,
International Coalition for Drug Awareness
www.drugawareness.org
__________________________________

“Fluoxetine-related death in a child with cytochrome P- 450 2D6 genetic
deficiency” Sallee FR, DeVane CL, Ferrell RE J Child
Adolesc Psychopharmacol 10(1):27-34 (2000)

ABSTRACT:

The clinical course of a 9-year-old diagnosed with attention-deficit
hyperactivity disorder, obsessive-compulsive disorder, and Tourette’s
disorder and treated with a combination of methylphenidate, clonidine, and
fluoxetine is described. The patient experienced over a 10-month period,
signs and symptoms suggestive of metabolic toxicity marked by bouts of
gastrointestinal distress, low-grade fever, incoordination, and
disorientation. Generalized seizures were observed, and the patient lapsed
into status epilepticus followed by cardiac arrest and subsequently
expired. At autopsy, blood, brain, and other tissue concentrations of
fluoxetine and norfluoxetine were several-fold higher than expected based on
literature reports for overdose situations. The medical examiner’s report
indicated death caused by fluoxetine toxicity. As the child’s adoptive
parents controlled medication access, they were investigated by social
welfare agencies. Further genetic testing of autopsy tissue revealed the
presence of a gene defect at the cytochrome P450 CYP2D locus, which results
in poor metabolism of fluoxetine. As a result of this and other evidence, the
investigation of the adoptive parents was terminated. This is the first
report of a fluoxetine-related death in a child with a confirmed genetic
polymorphism of the CYP2D6 gene that results in impaired drug metabolism.
Issues relevant to child and adolescent psychopharmacology arising from this
case are discussed.

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The Aftermath of Antidepressants

The Aftermath Of Prozac, Zoloft, Luvox, Fen-Phen, & Many Other Serotonergic Drugs

By Ann Blake-Tracy – Executive Director,
International Coalition For Drug Awareness

Ann Blake-Tracy has specialized for 10 years in adverse reactions to serotonergic medications. She is the executive director of the International Coalition for Drug Awareness (www.drugawareness.org) and author of the book PROZAC:PANACEA OR PANDORA?

WARNING: IT SHOULD BE NOTED THAT A GRADUAL TAPERING OFF OF MEDICATIONS IS SAFEST WITHDRAWAL METHOD TO AVOID SERIOUS WITHDRAWAL EFFECTS

Often there is the terrible withdrawal associated with the SSRIs. Unless patients are warned to come very slowly off these drugs by shaving minuscule amounts off their pills each day, as opposed to cutting them in half or taking a pill every other day, they can go into terrible withdrawal which is generally delayed several months. This withdrawal includes bouts of overwhelming depression, terrible insomnia and fatigue, and can include life-threatening physical effects, psychosis, or violent outbursts.

Note: Keep in mind that these drugs are all serotonergic agents and clones or “copy cat” drugs of Prozac – the first SSRI antidepressant introduced to the market in America. Basically what applies to one, applies to the others. For instance we have more data out on Prozac because it has been around longer, but as the mode of action is the same for all of these meds the effects will be the same for the other drugs on this list as it is for Prozac. If we are discussing one drug, similar effects would be expected from any other company’s version of the drug. In fact it would be more honest to give them the titles of Prozac #1, Prozac #2,Prozac #3, etc. rather than the brand names they have been given, from the second clone, Zoloft, to the latest Prozac clone, Celexa.

My concern is that each new SSRI introduced seems to be a little stronger on serotonin reuptake and therefore potentially more dangerous. And the all too common practice of going from one SSRI to another blocks additional receptors and magnifies the harmful effects of these medications. It is crucial to learn that according to medical research the theory behind this group of drugs is invalid. Known as serotonin reuptake inhibitors. They are designed to block serotonin in the brain, thereby increasing brain levels of this neurotransmitter. Yet for three decades researchers have been intensely interested in serotonin because LSD and PCP produce their psychedelic effects by mimicking serotonin. Elevated serotonin is found in: psychosis or schizophrenia, mood disorders, organic brain disease, mental retardation, autism and Alzheimer’s. While low levels of the metabolism of serotonin (which also produces high serotonin), are found in those with: depression, anxiety, suicide, violence, arson, substance abuse, insomnia, violent nightmares, impulsive behavior, reckless driving, exhibitionism, hostility, argumentative behavior, etc. The drugs increase serotonin and decrease the metabolism of serotonin leading to any and all of the above results. This information is extremely crucial for patients and physicians to learn as soon as possible. We have a high rate of use of these drugs nationwide. Raising serotonin and lowering the metabolism of serotonin in such a large number of people can produce very serious, widespread and long term problems for all of society.

So why are we now in the 90’s being told that increased serotonin is good for us? Is it because it is good for the pocketbooks of the manufacturers? One manufacturer is running full page newspaper and magazine ads and half hour TV infomercials to bring in over $7 million daily, while on the other hand they are settling Prozac suicide cases for huge amounts of money in exchange for silence from victim’s families on the details of those settlements. The silence in the court cases insures that the drug will be allowed to finish out its patent time, thus bringing in the highest possible profits for the company. They know that with $7 million coming in daily, they can afford to settle a large number of lawsuits and still come out “smelling like a rose” financially.

Eli Lilly has been sued for Prozac related deaths in numerous state and federal courts with most of these cases being settled or dismissed – many were dismissed due to the unethical manipulation of the Wesbecker verdict
(see time line for details).

We have witnessed no decrease in suicide, but increases in murder/suicide, suicide, unwed pregnancies, domestic violence, manic-depression, MS, hypoglycemia, diabetes, bankruptcies, divorce, mothers (parents) killing children, road rage, school shootings, cancer, Chronic Fatigue Syndrome, and Fibromyalgia since these serotonergic drugs have become so popular and I relate it directly to the effects of these drugs.

The death toll has continued to climb drastically since I wrote PROZAC: PANACEA OR PANDORA? Some of the cases you may be familiar with are:

1. Mr. and Mrs. Phil Hartman (Zoloft), Prozac was found in the van of Mark Barton, the Atlanta day trader, who recently killed his family and others in a shooting spree before taking his own life;
2. Neal Furrow, in LA Jewish school shooting was reported to have been court ordered to be on Prozac along with several other medications;
3. The Salt Lake Family History Library shooting;
4. School shootings in Littleton, Colorado (Luvox), Atlanta, Georgia, Springfield, Oregon (Prozac), and Caldwell, Idaho;
5. Another boy in Pocatello, ID in 1998 who in seizure activity from Zoloft had a stand off at the school;
6. 15 year old Chris Shanahan (Paxil) in Rigby, ID who out of the blue killed a woman;
7. The shooting at the lottery in Connecticut last spring by Matthew Beck (Luvox) that left five dead in a murder/suicide;
8. The New York City Subway bombing by Edward Leary (Prozac);
9. Nick Mansies (Paxil) in New Jersey who was convicted of killing a little boy who was selling cookies door to door;
10. In Orange County, CA Dana Sue Gray (Paxil) who co-workers described as a very caring nurse killed several elderly people;
11. Officer Stephen Christian (Prozac) one of the finest officers on the Dallas Police force, who ran into a police substation shooting at fellow officers and was killed;
12. 13 year old Chris Fetters (Prozac) in Iowa who killed her favorite aunt;
13. David Rothman (Prozac) killed two co-workers and himself at the Dept. of Agriculture in Ingelwood, CA;
14. Williams Evans (Zoloft) shot one co-worker at the Ohio Bureau of Employment Services before shooting himself in Columbus, OH;
15. Winatchee, WA where 43 people were wrongfully imprisoned in a false accusation of sexual abuse “witch hunt” fury started by a child under the influence of Prozac and Paxil;
16. Christopher Vasquez (Zoloft) killed Michael Morrow in Central Park;
17. Megan Hogg (Prozac) duct taped the mouths and noses of her three little girls and took a handful of pills; Vera Espinoza (Prozac) in Randolph, VT shot her small son and daughter before shooting herself;
18. An elderly man (Prozac) in Layton, UT axed his wife and daughter to death;
19. Margaret Kastanis (Prozac) used a knife and hammer to kill her three children before stabbing herself to death;
20. An elderly man (Paxil) in Dallas, TX strangled his wife before shooting himself twice in the chest;
21. Larramie Huntzinger (Zoloft) blacked out and ran his car into three young girls killing two in Salt Lake City, UT;
22. Mary Hinkelman (Prozac), a nurse in Baroda, MI shot her two small daughters and her sister before shooting herself;
23. Lisa Fox (Prozac) shot her small son and her dog before shooting herself in Brighton, MI;
24. Debi Louselle (Zoloft) shot daughter and then herself in Salt Lake City, UT;
25. A father in Wyoming shot his wife, daughter and baby grand-daughter then himself after only days on Paxil;
26. A mother (Prozac) in Pleasant Grove, UT killed her 17 year old son with a sledge hammer while he slept before she attempted suicide by drinking Drano;
27. Larry Butz, a superintendent of schools in Ames, IA shot his wife, son and daughter before shooting himself – many cases pending in court are not mentioned.

This is only a handful of MANY, MANY more cases – there would not be room for anything else if I continued listing the cases.

A few additional famous victims: Princess Di (Prozac) and Dodi Fayed -via their driver Henri Paul (Prozac), Monica Lewinsky (Prozac, Zoloft, Effexor, Serzone and Phen-Fen), Chris Farley (Prozac), Pres. Clinton’s ex-partner Jim Mc Dougal (Prozac), Abby Hoffman (Prozac), Del Shannon (Prozac), Danielle Steele’s son (Prozac), INXS singer Michael Hutchence (Prozac), Sarah – Dutchess of York (Phen-Fen)

The latest figures show Prozac has about 44,000 adverse reports filed with the FDA. Out of those reports there are about 2,500 deaths with the large majority of them linked to suicide or violence.

The suicide statistics relating to women are shocking. According to the CDC there are about 30,000 suicides yearly in the United States. Out of those about 6,000 are women – a ratio of about 4.3 to 1, male to female. About twice as many women as men are treated for depression demonstrating that generally men are more than 8 times as lethal in their suicidal gestures as women. Women were known to use less lethal means until the SSRI antidepressants hit the market. But on Prozac and Paxil, women committed 40% of the suicides – many were strikingly violent and clearly leaving no
means for rescue. (Remember that because Prozac was the first of this group of drugs its track record gives us a vision of what is to come with other serotonergic antidepressants, especially when they are so powerful in the reuptake of serotonin.)

TIME LINE OF CRITICAL INFORMATION DISCOVERED SINCE THE BOOK:

*NOTE: Any documents beginning with PZ are Lilly documents on Prozac which have been ferreted out by attorneys and are now being used in lawsuits against the drug company. (Christian vs. Eli Lilly, by Vickery & Waldner, Houston, TX)

* Mid 1950’s: Dr. Felix Sulman began his research on those who suffer from high serotonin levels because of an inability to metabolize serotonin. He found that serotonin is a stress neuro-hormone leading even rabbits, the most docile of creatures, to be aggressive. He coined the term “serotonin irritation syndrome.” He found that those who were unable to break down serotonin would have the levels increase. They were in effect being poisoned by the serotonin produced by their own bodies, the irritation victims suffered from migraines, hot flashes, irritability, sleeplessness, pains around the heart, difficulty in breathing, a worsening of bronchial complaints, irrational tension and anxiety. . . horrifying nightmares. It also caused his volunteers to sleep badly – that is, always on the edge of consciousness so that they were not properly rested – and to wake after only a few hours of sleep.” (sleep apnea) He also found it caused pregnant women to abort.
* October, 1977: Slater, et.al., Inhibition of REM Sleep by Fluoxetine, a Specific Inhibitor of Serotonin Uptake, October 1977, at p. 385 – Prozac was found to affect sleep habits, specifically to suppress deep sleep, which the scientists call REM (rapid eye movement) sleep in cats. By the fourth day of drug treatment the cats receiving the larger doses, which had been friendly for years, began to growl and hiss. After cessation of the drug treatment, the cats returned to their usual friendly behavior in a week or two; those on the higher doses recovering more slowly. – – 1977: [PZ 1298 1999] “A total of six dogs from the high dose group were removed from treatment … due to severe occurrences of either aggressive behavior, ataxia, or anorexia.”]
* July 31, 1978: [PZ1061 1025-28, July 31, 1978] Human subjects began to be used by Lilly in controlled clinical trials. The first group of patients showed no improvement in their depression, but there were a “large number of reports of adverse reactions.” The first human to receive Prozac experienced “dystonia resembling an extrapyramidal reaction” – an uncontrollable, Parkinson-like shaking or trembling.
* July 23, 1979 [PZ 1297 969] The clinical studies in depression showed that “some patients have converted from severe depression to agitation within a few days; in one case the agitation was marked and the patient had to be taken off drug. In future studies the use of benzodiazepines to control the agitation will be permitted.”
* August 3, 1979: The clinical trials excluded patients who had serious suicidal risk. [E.g. control #001519, IND Protocol No. 14, August 3, 1979; PZ1135 695, July 2, 1986 memorandum of Dr. Wernicke].
* December 17, 1984: [PZ 65 449, report of Lilly to FDA] Lilly reported to the FDA that benzodiazepines and other sedatives were given with Prozac throughout the clinical trials. This was to help offset the stimulant effect of the drug. In a memorandum of Lilly scientist Charles Beasley [PZ 541 2007-08] issues of “agitation vs. sedation” and concomitant sedative medications like benzodiazepines (to control the agitation) are discussed. Concerns are that agitation in a suicidal patient can induce suicide.
* March 3, 1986 Lilly controlled the flow of information to the FDA and decided that suicide data on Prozac should not be evaluated, “in the safety-update for the FDA the number of suicides and suicide attempts will not be especially evaluated.” [PZ 879 1966, March 3, 1986 telex]
* September 12, 1986: German BGA very concerned with the risk of suicide and ultimately approved Prozac on the condition that physicians be warned of the risk of suicide and told to consider using sedatives and closely monitor patients. [PZ 878 1383, report of Lilly consultant Pohlmeier; PZ 2467 299, September 12, 1986] Lilly actually warned physicians in Germany and other countries that this measure “can be necessary” to minimize the risk of suicide, [PZ 1341 402, December 6, 1989 German warning; PZ 2469 490]
* February 7, 1990: In response to the Harvard study, Teicher, et al., Lilly’s top scientist, Leigh Thompson, told his fellow executives that “Lilly can go down the tubes if we lose Prozac”. [PZ 1941 827, February 7, 1990]. In the ensuing months Dr. Thompson spoke frequently with his principal FDA regulator about the issue, once at 6:15 in the morning. [PZ 391 1959, July 18, 1990]. Lilly later described the man as “our defender”. [PZ1941 2256, September 12, 1990]
* May 29, 1990, Lilly added “suicidal ideation” in the section dealing with post-marketing reports. [PZ883 562, July 26, 1990 memorandum]
* September 14, 1990: Contrary to the advice of his staff, Dr. Thompson told the Eli Lilly Board of Directors that suicide and hostile acts were probably, caused by the patients’ underlying disorders rather than Prozac. [PZ542 2101, September 14, 1990; PZ4002 889, Board Minutes]. The staff was concerned because they knew that this issue was never studied during the clinical trials.
* September 11, 1990: Note from Dr. Bruce Stadel, Chief of the Epidemiology Branch, attaching an analysis done by Dr. David Graham, Section Chief within the Epidemiology Branch, of Lilly’s July 17, 1990 submission to the FDA on the Prozac/suicidality/violence issue. The following factors were (a) brought to the attention of those in the higher echelons of the FDA, but (b) ignored, discounted or “trashed” by them: #1 Lilly’s analysis improperly excluded 76 out of 97 suicides; as Dr. Stadel expressed it, “[i]t is inappropriate in a safety analysis to exclude such a large proportion of case”; #2 Lilly admitted that its clinical trials “were not designed for the prospective evaluation of suicidality” and that “[i]n these trials, patients with current suicidal ideation were excluded”; #3 Lilly admitted that the HAMD-3 rating scale it used to assess suicidality in clinical trials was inadequate; and that Lilly’s statements about violence only demonstrated “how great under-reporting is” and that “[t]he actual data showed a higher percentage of treatment-emergent suicidality among fluoxetine (2.9% than tricyclic (0.8%) patients . . . [which percentage] was similar to that reported by Teicher.”
* July 1, 1992: A study lead by Dr. Lorne Brandes of the Manatoba Institute of Cell Biology in Winnipeg, Canada was published in CANCER RESEARCH linking the two most popular anti-depressants, Elavil and Prozac to cancer.
* 1994: A study headed by Howard Markell published in The Journal of Pediatrics showed LSD flashbacks and LSD reactions induced by Prozac.
* June 9, 1994: The New York Review of Books article by Dr. Sherwin Nuland slams Peter Kramer for pushing Prozac in his book Listening to Prozac. He pointed out that all docs are taught in med school this little poem about serotonin: “This man was addicted to moanin’, confusion, edema, and groanin’, intestinal rushes, great tricolored blushes, and died from too much serotonin.” He listed constriction of lungs and intestines, diarrhea, wheezing, flushing, mental confusion, tightening of bronchioles, and lessening conscious control over behavior from increases in serotonin. “Moreover, . . . it is still too early to arrive at a reliable estimate of possible dangers that may appear in the long term,” and 15% dropped out of the clinical trials on Prozac because of adverse reactions. He also discussed the similarity of serotonin to the psychedelics like LSD and PCP.
* November, 1994: Krystal JH, Webb E, Cooney N, et al., “Specificity of Ethanol-like Effects Elicited in Serotonergic and Noradrenergic Mechanisms,” ARCHIVES OF GENERAL PSYCHIATRY, Vol. 51, Issue 11, pgs 898-911, 1994 demonstrated that an increase in brain levels of either of two neurotransmitters, serotonin or noradrenalin, produces:
#1 a craving for alcohol,
#2 anger,
#3 anxiety.
They found this to be especially true for those who have a history of alcoholism. An increase serotonin in turn increases noradrenalin. Numerous reports have been made by reformed alcoholics who are being “driven” to alcohol again after being prescribed a serotonergic drug. And many other patients who had no previous history of alcoholism have continued to report an “overwhelming compulsion” to drink while using these drugs.

A few personal accounts:

#1 A young woman, a recovering alcoholic, reported that during the eight month period she had been using Prozac she found it necessary to attend AA meetings every day in order to fight off the strong compulsions to begin drinking again.
#2 In the Southeastern United States a middle aged psychologist, also a recovering alcoholic, after being prescribed Prozac, found herself needing to attend AA meetings morning, noon, and night to keep from destroying the sobriety she had achieved.
#3 A young father, who was Mormon and had never before in his life used alcohol, found himself drinking Ever Clear and exhibiting bizarre as well as violent behavior, after being prescribed Prozac and Ritalin.
#4 A young mother who had never used alcohol before began drinking large amounts within weeks of being prescribed Prozac and quickly found herself committed to a mental institution due to the psychotic behavior that resulted. Added to her Prozac prescription were anti-psychotic meds and electric shock treatments. She then began to experience seizures and was started on anti-seizure meds.
#5 A concerned neighbor reported her friend was drinking straight Vodka on a regular basis after being prescribed Zoloft. #6 A daughter reported her father, sober for 15 years, began drinking again on Prozac.

* December, 1994: Not guilty verdict on Wesbecker wrongful death suit against Lilly’s Prozac.
* Treatment emergent suicidality with Prozac has been demonstrated to be two to three times higher than any other anti-depressant. (Jick, et al., Antidepressants and Suicide)
* May, 1995: Judge John Potter who presided over the Wesbecker case filed documents to demand that Lilly be forced to disclose the secret deal they made with the plaintiffs to withhold very damaging evidence in exchange for settlement. In his pleading to the court Potter stated, “Lilly sought to buy not just the verdict, but the court’s judgment as well.” Potter accused Lilly of “giving the verdict the widest possible publicity” accompanied by the claim that Lilly had “proven in a court of law that Prozac was safe.” Furious with Lilly’s attempt to turn his courtroom into an advertising agency for Prozac, he claims his motion reflects “the court’s duty to protect the integrity of the judicial system.” He believes, as do prominent legal ethicists, that a full and open disclosure of the terms of the settlement is a necessary public safety issue.
* July, 1997: Mayo Clinic found that the increased serotonin, which produces blood clotting, was causing a gummy glossy substance to build up on heart valves. Dr. Heidi Connolly with the Divisions of Cardiovascular Diseases and Internal Medicine, who headed the study stated, “We do know that fenfluramine and phentermine [Fen-Phen] alter the way the brain chemical serotonin is metabolized, and serotonin that circulates in the blood can cause valve injury.” Fenfluramine produces a rapid release of serotonin, inhibits serotonin reuptake, and may also have receptor agonist activity. The study’s revelations should send a loud and very clear warning throughout the medical community concerning all serotonergic medications.
* August 25, 1997: Letter to Ann Blake-Tracy, “I caught the last part of your presentation on Radio Station KEX, Portland, while flipping through the dial last night. I was flabbergasted to hear you speak of the horrible potential side effects from Prozac, which I have been taking for approximately four years, particularly since I have been diagnosed recently with cardiomyalgia, severe artery disease, congestive heart failure and also Fibromyalgia. (I was a very “well” person prior to taking the Prozac and am now exhausted all the time, with horrible aching joints and considerable pain and a massive heart problem.) The adverse cardiovascular effects from Prozac, the one drug in this class of drugs out long enough to have somewhat of track record, are listed in the drug information sheet put out by the manufacturer. The “frequent” effects listed are hemorrhage and hypertension. The “infrequent” effects include very serious adverse effects: congestive heart failure, myocardial infarct, tachycardia, angina pectoris, arrhythmia, hypotension, migraine syncope and vascular headache.
* September, 1997: Redux and Phen-Fen were pulled from the market.
* October 20, 1997: Dr. Candace Pert, Research Professor at Georgetown University Medical Center, past head of the brain chemistry department at the National Institute of Health, and author of the new book, MOLECULES OF EMOTION, sounded an alarm in TIME, October 20. She stated, “I am alarmed at the monster that Johns Hopkins neuroscientist Solomon Snyder and I created when we discovered the simple binding assay for drug receptors 25 years ago. Prozac and other antidepressant serotonin-receptor-active compounds may also cause cardiovascular problems in some susceptible people after long-term use, which has become common practice despite the lack of safety studies.”
As we are being led to believe these drugs produce effects only in the brain, Dr. Pert accuses the medical profession of oversimplifying the action of these drugs and adds that “the public is being misinformed about the precision of these selective serotonin-uptake inhibitors.” It is critical that both physicians and patients be made aware of these adverse physical reactions. She points out that the medical profession not only oversimplifies the action of these drugs in the brain, but “ignores the body as if it exists merely to carry the head around!” And that, “these molecules of emotion regulate every aspect of our physiology.” The body plays a very significant role in how we feel and act the way we do. This fact can no longer be ignored. Serotonin and serotonin receptors exist throughout the body, as well as the brain, and every aspect of the body’s physiology is affected by these serotonergic medications. In fact approximately 90% of the body’s serotonin is produced in the intestinal tract. According to Dr. Michael Gershon of New York’s Columbia Presbyterian, this is the reason why Prozac produces so many gastrointestinal side effects.
* March, 1998: Two new studies published. One that shows Prozac so strongly inhibits one particular serotonin receptor that this produces both obesity and seizures and the other discusses the blockage of muscle and neuronal nicotinic acetylcholine receptors indicating interactions between the serotonergic and cholinergic systems in the central nervous system.
* April, 1998: Our next generation of guinea pigs – one month before a 15 year old on Prozac, Kip Kinkel, in Springfield OR killed his parents and two classmates the American Psychiatric Association and the American Academy of Pediatric Psychiatrists asked the FDA to consider the serotonergic antidepressants for use in children as young as two and drugs for anxiety, aggression and manic depression in babies only one month old! The use of Prozac among young children ages 6 – 12 has increased an alarming 400% from 1995 (51.000 new prescriptions) to 1996 (203,000 new prescriptions).
* June, 1999: CLINICAL PSYCHIATRY NEWS reported that Dr. Malcolm Bowers a psychiatrist at Yale has found that physicians are not paying enough attention to patient factors that could make initiation of SSRIs dangerous. He found that “SSRI-induced psychosis has accounted for 8% of all general hospital psychiatric admissions over a recent 14-month period.” And “What is surprising is that this particular group of side effects is really underplayed.” (The 8% figure represents over 150,000 SSRI induced psychotic breaks per year!!!!!!!)

WARNING: Children so often get coughs and colds, yet using a cough or cold medication with dextromethorphan could cause the serotonin syndrome, a very serious and potentially fatal adverse reaction and/or produce PCP reactions.

Serotonin syndrome remains an often misdiagnosed or unrecognized fatal reaction due to the medical profession being so uninformed about this drug-induced disorder.

Developing brains are far more vulnerable than adult brains and brain damage generally becomes more apparent after the brain is fully developed, rather than immediately. Increases in cortisol produce brain damage while medical research shows that one single 30mg dose of Prozac DOUBLES the level of cortisol. This drastic increase in cortisol causes a multitude of serious physical reactions including impairment of linear growth, as well as impairing the development and regeneration of the liver, kidneys, muscles, etc. In light of so many unspeakable tragedies, I have grown weary of all the silly philosophical discussions we have heard since Kramer’s LISTENING TO PROZAC came out. Patients are dying or having their health destroyed mentally as well as physically (when do we begin to discuss the very serious physical side effects associated with high levels of serotonin?). These patients and their families are frantically searching for answers while this research sits right under our noses and could easily be made available to them. The widespread use of Prozac and its clones is not a statement of either their safety or their effectiveness. It is a statement about the effectiveness of an infinite marketing budget and incredible advertising campaign! These drugs have very serious physical side effects, as well as dangerous psychiatric side effects.

To prevent further tragedy this medical research must be acknowledged and addressed in headline news without delay rather than remain buried in seldom read medical research documents as has been the case in the past with other mind- altering medications, once thought to be safe, which were subsequently prohibited by law, i.e. LSD, PCP, cocaine, etc.

PRAISE FOR PROZAC: PANACEA OR PANDORA?

“I started having bad reactions . . . Oct ’96 I found Prozac to be causing joint and muscle pain itself . . . signs of Cushing’s Syndrome. . . I was very pro-Prozac until last October and wouldn’t have listened to anything said against it until I got problems (thought it was saving my life, while all the time it was insidiously and interested but quite skeptical. However, since reading it and having suffered so many problems with Prozac, I have come to the conclusion that the book is brilliant, and a life-line as far as I am concerned. I tried to fault the research and reasoning, but could not and still can’t. I would like to extend my thanks to you for your heroic stance on this enormously important issue. I have tremendous respect and admiration for your hard work, determination and courage in pursuing this subject so vigorously, against so much powerful opposition for the benefit of people like me. Your integrity puts many, if not most doctors and psychiatrists to shame. It is reassuring to find that there are a few people who are prepared to fight for the truth for the benefit of mankind.” Oct. 1998 note from a British nurse

“PROZAC: PANACEA OR PANDORA? is an incredible compilation of medical data that will lay the groundwork to educate other professionals and the general public about the new SSRI antidepressants – Prozac, Zoloft, Paxil, Luvox, Effexor and Serzone.” (Jeff Wise, psychologist, Salt Lake County Drug and Alcohol Abuse )

“In 15 years of reading books on drugs I have never read a book with more information or so well documented as PROZAC: PANACEA OR PANDORA?” (Dr. Kevin Millet, Bountiful, UT)

“As I lecture to physicians nationwide on the medical use of psychoactive drugs PROZAC: PANACEA OR PANDORA? always accompanies me in my brief case.” (Dr. Bruce Woolley, neuropsychopharmacologist, Brigham Young University)

“I found PROZAC: PANACEA OR PANDORA? fascinating reading and the most complete analysis of the various factors pertaining to the Prozac controversy.” (Attorney Donald Sokol, Susanville, CA)

“PROZAC: PANACEA OR PANDORA? literally saved my life, and if I’d known about it a year earlier, could have saved me untold grief and agony as well. It is the only collated, comprehensive source I know of for this information , . . .. this book described everything that had happened to me in great detail, gave scientific reasons why it happened, backed it all up with solid research, included testimonials from hundreds of others in the same situation, it immaculately details, explains, and refers one to the latest research on a whole hornet’s nest of ‘atypical’ side-and/or after-effects from the use of these antidepressants. It also contains information on how to reduce the severity of problems encountered while starting on or going off these meds.” (Nick Jameson, Prozac patient)

“Magnificent! This text is a monument to Ann Tracy’s tenacity and love for her fellow human beings.” (Dr. Paul Kennedy, N.J.)

“PROZAC: PANACEA OR PANDORA? has not left one question about these drugs unanswered! Ann Tracy has covered them all.” (Margaret McCaffery, N.Y. who lost her daughter, a neurosurgeon, in a Prozac suicide)

“The work Ann Blake-Tracy is doing is very important and she is truly a heroine.” (Dr. Candace Pert, Washington, DC, one of the two developers of the serotonin binding process which made possible the development of the serotonergic drugs. Dr. Pert has boldly stated, speaking of these serotonergic medications, “I am alarmed at the monsters I created!”)

WARNING: In sharing this information about adverse reactions to antidepressants I always recommend that you also give reference to my CD on safe withdrawal, Help! I Can’t Get Off My Antidepressant!, so that we do not have more people dropping off these drugs too quickly – a move which I have warned from the beginning can be even more dangerous than staying on the drugs!

The FDA also now warns that any abrupt change in dose of an antidepressant can produce suicide, hostility or psychosis. And these reactions can either come on very rapidly or even be delayed for months depending upon the adverse effects upon sleep patterns when the withdrawal is rapid! You can find the CD on safe and effective withdrawal helps here: http://store.drugawareness.org/

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Redux caused my Pulmonary Hypertension

“I had never been diagnosed with any of these things before taking Redux.”

 

Hi, My name is Bev and I took Redux for approximately 9 weeks ending with the drug recall 9/12/97. While on the drug I had a lot of symptoms of flushing especially in the face, dizziness when laying down where the room would spin around. I was told this was just getting use to the drug. I was more agitated than usual, but I did not notice any other physical problems until a few month off the drug when I had heart fluttering and what felt like skipping beats. I started having one flu like symptom one after another for about 9 months and was told I had bronchitis, sinusitis, asthma during this period. I never related any of this to the drug. During this time I had 3 echoes done two by the drug manufacturer since I was on a clinical trial and it showed that my valves had 3 valves with trivial insufficiency. I thought I got off pretty lucky.

However, by the close of the summer of 1998, (one year later) I was getting short of breath and having problems just driving to the store a few blocks away and stepping down on my feet, my ankles would hurt. There was some swelling but I believe I was hoping it was from arthritis. I also had trouble with tingling in my hands and feet almost like little needles poking you. I would toss and turn and have a difficult time falling asleep and when I did I would sometimes jump up feeling like I could get any air. I remember when we lit a fire in the fire place that winter that I went into a real allergy attack from the smoke. I was diagnose with dyspnea (shortness of breath) in 9/99. I had a scan done to see if I had an embolism and there was none. Blood work was completed and they check for arthritis and many other types of conditions and the only thing that was abnormal was my blood gases which said my oxygen was at 67 very low. I was suffering from confusion and forgetfulness. I had stopped menstruating for almost a year and then had terrible bleeding for 8 days straight. That has not finished with me yet. I am 53 years old and I know it should stop I hope soon. I was encouraged by friends to get another echo done but to have a stress echo done this time. I went to UC San Diego and had my echo performed and at that time it was discovered that my mitral valve was now mild and my tricuspid valve was moderate and that it appeared to be normal left ventricular systolic function but the right heart was now mildly enlarged and the baseline echocardiography suggests mild pulmonary hypertension with stress. The doctor wanted to perform a right heart Catherization soon and I went back there again for that procedure and to perform a sleep study. It was determined at that time that I did have pulmonary hypertension, but secondary to sleep apnea.

Now the problem is what caused it. I had never been diagnosed with any of these things before taking Redux so why would they all start to show up now. Anyway, now I must were a mask to bed every night that lets in enough air so I can breath. I believe that this is all related to taking that drug. I wonder how many others out there have had similar experiences.

Bev

5/5/2000

This is Survivor Story number 22.
Total number of stories in current database is 96

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Withdrawing from Paxil has been a Nightmare

“Feelings of suicide and hopelessness are worse now than ever.”

 

I liked your comments on Prozac, Paxil, and Zoloft. I have been on Paxil since 1995, and it has been a nightmare. I am slowly getting off the drug on my own, without telling my doctor. Believe me, I am cutting back VERY slowly because of how long I have been on it. I have gotten worse over the years, and not better, and have told my doctor so, but to no avail. Feelings of suicide and hopelessness are worse now than ever.

I know that many people wish there was a drug that really would help without the incredible side effects, such as weight gain, etc. By the way, I have gone from 180 (my ideal weight) to 240 pounds during the time I have been on Paxil. That in itself is depressing.

Tom Gadowski
27627 El Capitan Dr.
Warren, MI 48092-3078
(810) 751-6791

5/2/2000

This is Survivor Story number 23.
Total number of stories in current database is 96

 

 

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Nurse Tells of Horrors after Gaining Weight on Prozac

“Prozac is a dangerous drug!!!!! It has changed my body, my health, my financial status, influenced my marital status and almost destroyed me.”

 

Hi Ann Blake-Tracy,

Tomorrow will be 77 days off Prozac.

I feel relieved and elated that I have made it this far…and feel good. I hope my story can help some of the readers, as I have been on a real rollercoaster ride with this drug.

Let me start at the beginning. I have been prescribed and have taken sporadically antidepressant drugs for about 29 years. I have been diagnosed as bipolar but have neither manic episodes or deep depression. I do have time to time mild depression which causes some anxiety in my day to day living.

Three years ago a psychiatrist, seeing me for 10 minutes as a requirement as an adjunct to my one on one therapy with my therapist, prescribed Prozac. I was started on 20mg per day and within 1 day could feel it “kicking in” and making the world tolerable again. I immediately felt that I had really needed this drug..and why did I wait so long to feel better….as the weeks wore on however, the initial good feelings for my fellow man were replaced by transient feelings of anxiety…feeling that I couldn’t cope with things, situations… and an ongoing feeling that I didn’t want to deal with anything anymore.

I also started to gain weight…..mostly craving fast food and sweets…..at the end of 3 years I have gained 65 pounds and have the appearance of a cushinoid patient with upper body weight, buffalo hump, facial weight. I look different..I don’t look healthy. I also quit a job that I had for 7 years and started job hopping…had 4 jobs in one year. Financially..somehow I went from good credit…to bad credit with my 2nd mortgage becoming a reality to get my life back. I also divorced a husband of 26 years and remarried…but I believe that was a good choice. Would I have made different choices without the Prozac….I don’t know…….I weaned myself off the drug after reading your book and feel so much better mentally…..I have started another job and have stuck to it…I feel I have myself back again.

The only problem is the weight…..I can’t seem to get it off………Do you have any suggestions on diet types for this problem? I know the Cortisol is directly at fault…does it continue??? How do we stop it? I am a nurse and have been trying to research it on my own…what I have found is disheartening…..effects may last 2 years…….any suggestions….

I have also sent your book to my daughter who was also on Prozac..and my other daughter on Paxil….. Both are off the drugs after weaning…and doing better…..Prozac is a dangerous drug!!!!! It has changed my body, my health, my financial status, influenced my marital status…..and almost destroyed me……Please write back on any suggestions you may have on diet to crack this weight..I am 52 years old.
———–

Note from Ann Blake-Tracy:

Whatever you do as an ex-SSRI user, DO NOT try the high protein diet craze that is making a come back in spite of destroying the health of so many in the 1970’s! Ex-SSRI users are becoming EXTREMELY ill trying to follow this diet. I personally believe the reason for that is that the serotonergic drugs, while impairing one’s ability to break down serotonin, also impair one’s ability to metabolize proteins. This would make high protein diets very dangerous for them. Good nutrition, walking, sufficient water intake, proper sleep, and good fats Vs bad fats have always been the keys to weight loss. Check out Udo Erasmus’ book, “Fats the Heal, Fats that Kill” at www.edoerasmus.com.

Susan in Michigan

4/17/2000

This is Survivor Story number 24.
Total number of stories in current database is 96

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Spaced Out on Zyban

“I was a very frightening experience.”

I took Zyban (Wellbutrin) to help me stop smoking. Was on it for 2 weeks and never have I felt so awful! I felt “spaced out”, nervous, crying spells, jittery feeling, and just didn’t feel myself…felt almost out of control. I went off it and almost immediately felt myself again. It was a very frightening experience and I certainly have no wish to repeat it.

glayres@bmts.com

4/13/2000

This is Survivor Story number 25.

Total number of stories in current database is 96

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Meridia Stole My Health

“…the FDA was warned by their own experts not to release this Meridia and it got on the market anyway.”

 

I am a 62 year old mother of three grown sons. I have been exceptionally healthy all of my life. On 9/4/99, my birthday, I looked in the mirror and said to myself, “Jane, you would never have gotten those lines over your lip if you had never smoked.” I then started on my campaign to stop smoking and I did just that. When I grew up, all the movie stars smoked, it was glamorous, my parents smoked. But, I made a decision and this time I would make it. I DID!!! Only to have this devastating thing happen to me. I didn’t have any illness from smoking and decided I wasn’t going to.

I stopped smoking but gained 22 lbs. So, on my yearly visit to my gynecologist, I told him about the weight gain and he put me on Meridia. I had never heard of this drug but, had high hopes for results. I am a dancer and (vain about my looks) and this 22 lbs. seemed just too much. I breezed through the menopause and was a little heavier than my younger days but still an attractive, well proportioned, active lady. I was raised to think “Wellness”. My mother was a nurse and my Irish father thought eating right was the answer, and that young women should not be to thin. So, I think I had a very healthy outlook and just tried to reject illness. Besides having healthy genes, and youthful genes, I look at least 20 years younger than I am. I was so fortunate!!!

Shortly after starting Meridia, my right heal began to hurt, shooting pain near the Achilles tendon. I started walking on breaks at work, so I attributed it to that. My balance also seemed a little off. Also, there was a drastic change in my vision, but, being me, I told myself that I was finally going to need reading glasses. Still thinking “Wellness” but trying to admit that I was getting older. I visited an eye doctor and he asked if I was a diabetic. I am not and have never been. So, he said to go get checked for diabetes, since he had never heard of going from a -150 to -275 so quickly, and if I was diabetic, maybe when I was on medication, my vision would return to normal. All the diabetic tests were normal. My gynecologist ran the test. At that point, I mentioned to the doctor’s nurse that I was getting suspicious of the Meridia. And she snapped at me, “Then you must be one of the one’s that can’t take this drug.” I was furious, but kept my mouth shut. I have since confirmed to her my suspicions and asked that she tell the doctor and not to prescribe this drug to anyone else. Now, she has humbled a little.

This is getting much to long, doctor. Other symptoms: Broken bones in my feet. Confirmed stress fractures in right foot and I am being checked on the left foot this week. Dizzy spells, loosing my balance, staff infection right hand, from a slight stick to palm which did not even bleed. A rash on my nipples that is driving me crazy. After taking Augmentin for the staff infection, and getting a big dose of something in my butt, an antibiotic, I got something else, the exterior areas of my vagina became bright, maroonish, red and burned. This has gone away. There are some other symptoms but I have taken up enough of your time. I am really scared and this is why. As healthy as I am, with only the one doctor, the gynecologist, until this all occurred, I have been in touch with a legal firm out of Arizona and the young, legal asst., college student, pre-law, has told me that I may be experiencing decalcification of the bones. They have several people who have contacted them and the 19 year old boy, brilliant, has done a lot of research.

Well, that’s most of the story. I am very angry and scared. I may not be out of the woods. The law firm has not accepted my case yet although they represent a 29 year old girl, who is a vegetable, she admitted she took more Meridia than she should have. Her husband has to do everything for her and their young children. They are supposedly are suing for $25,000,000.

I also have done a lot of research but, have not been to a medical library and just simply don’t under the serotonin connection. I am very intelligent and perceptive, and thanks to my intuition, I only took this KILLER drug for 2 months and was off of it for a week when I took the Augmentin. I had three 10 mg. pills left and took them but, as mentioned above, (not all three at once). I decided not to get the third refill. I guess I am one of the lucky ones. I may never be able to dance (could out dance any 25 year old). And, I may never regain my good vision. I am really worried about these stress fractures. I am calling to order your book tomorrow and maybe the serotonin connection might make a little sense to me.

Thank you so much for taking time to read this long email. You must be a very nice lady to care so much. Doctor, the FDA was warned by their own experts not to release this Meridia and it got on the market anyway. Knoll waged a major P.R. and exhaustive marketing program to fool the American people again. I consider these people criminals and I plan to expose them if it’s the last thing I ever do.

 

4/5/2000

This is Survivor Story number 26.

Total number of stories in current database is 96

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My 18-Year Old’s Bizarre Behavior on Prozac

“At no time …did any one mention Prozac’s side effects.”

My 18 year old son has been on Prozac for the last year and a half.
Initially, I brought him to a counselor for some mild anxiety he was experiencing (shyness in social situations, etc.) The counselor (a licensed MSW) prescribed Prozac, saying that it would greatly reduce Jeff’s anxiety. Indeed, after two weeks Jeff reported feeling better, being more relaxed in school and in social situations. Over the next 6 months or so, however, I began to notice some disturbing symptoms (excessive sleepiness at times and at other times extreme agitation along with an inability to concentrate on schoolwork).I told his family doctor, who suggested cutting his dose of Prozac, from 20 mg. to 10 mg. Shortly after this time, Jeff began to develop a severe drinking problem. He frequently came home so intoxicated that he could not stand and remembered nothing the next morning. His grades in school also started plummeting: during his senior year in high school, his grades went from B+ to failing. He was extremely agitated, anxious, unable to sit still or focus. At this point his counselors recommended that his Prozac be upped from 10 to 20 mg.

Things went from bad to worse-his drinking increased, he barely graduated from high school (he was on home study because he was exhibiting bizarre, sometimes threatening behavior in school, and was suspended).At no time during this period did any one mention Prozac’s side effects or the possibility that Jeff was having a serious reaction to this drug.

Finally, towards the end of summer ’99, when he picked up his prescription from the pharmacy, he read the label and noticed some of the possible side effects, pointing out to my husband and myself that these were the same things he’d been experiencing. We made a family decision to stop the Prozac, not realizing that the fun was just beginning. About a week after stopping the Prozac, Jeff began to have panic attacks (something he’d never experienced before).Along with the shaking, irregular heartbeat and anxiety, he experienced strange sensations in his head and a buzzing sound in his ears. We went to see his doctor, who didn’t make the connection-he sent him to a psychologist to treat the panic attacks, not suspecting that the problem might be Prozac withdrawal (nor did I). For the past 2 months, his symptoms have grown steadily worse: he’s been in the emergency room for severe headaches, has seen a neurologist, had many expensive tests, and been diagnosed with Migraine.

No one made the connection between his symptoms and the fact that he had stopped the Prozac abruptly (all doctors knew of his decision). It wasn’t until I saw Dr. Tracy on the Leeza show recently that I started to suspect that this might be the problem. Since then I’ve been researching Prozac on the internet and am amazed at the information I’m finding! I’ve spoken to Jeff’s doctor who was as surprised as I about these complications (I printed and mailed him lots of info.)I will order your book, as I want to know what I can do to help my son at this point apologize at the length of this e-mail, but I had to tell this story to someone.
Thank you.

Followup Letter to Dr. Tracy:
Dear Dr. Tracy,
Thank you for your kind response to my e-mail. It’s obvious that this is an issue very close to your heart. It’ s easy for me to see how frustrating this battle can be: the more information that I find on this topic, the more appalled I become that the medical and psychiatric professions are allowing this to happen to unsuspecting and trusting patients. Amazingly, Jeff seems to be doing much better. Just within the past week, his headaches have all but disappeared, and his anxiety level is greatly diminished. It’s been about 2 1/2 months since he stopped taking the Prozac- from what I’ve read however there can be delayed withdrawal reactions, so I’m not sure we’re out of the woods yet. I’ve been very busy printing information that I find on the internet and sending Jeff’s doctor and counselors letters and packets of information. My hope is that they will at least begin to question these drugs and do some research on their own. I’d like to show you an excerpt from the letter I wrote to the psychologist Jeff was referred to for the panic attacks he experienced shortly after discontinuing the Prozac. I am particularly annoyed with this doctor because he told me that Jeff’ panic attacks were the manifestations of OCD and that he needed to be on medication. From letter to Dr. Robbins: Coincidentally, now that Jeff’s withdrawal symptoms seem to have abated, he is much more like the son I once knew. He’s more relaxed, he’s stopped drinking, his sense of humor is back, and he’s actually able to focus on schoolwork ( he got an A on a recent College Comp. paper.)What does this say about Prozac? Basically, I feel that this drug took my son away from me for two years! I have also written a letter to the Rochester editorial page; a Speaking Outessay. I’ll let you know if they print it. If there’s any way I can help you with this cause, please let me know .I feel very strongly about it: this drug took my 16 year old son, who had been identified as gifted, was well-liked by his peers, and had a great sense of humor, and reduced him to a barely functioning shell of a person. I am thankful to you and God for rescuing us from this terrible shadow that hung over our lives.

Yes, I would like my e-mail (the original and this reply) posted on your website. You may include my first name and e-mail address. I would also like to remind people who’ve had negative experiences with Prozac or another anti-depressant to send a med-watch complaint to the FDA. The number for your local FDA is in the Federal organization section of the phone book. There is also a link from this ICFDA web site.] The more complaints they get the more likely it is they’ll investigate (I hope, unless they’re in this with the drug companies- but that’s a whole different topic)

Patti582@aol.com

2/27/2000

This is Survivor Story number 27.

Total number of stories in current database is 96

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Study Links Older Bipolar Drug to Fewer Suicides

http://www.nytimes.com/2003/09/17/health/17SUIC.html

Dr. Frederick K. Goodwin, senior author of the study and director of the psychopharmacology research center at George Washington University Medical Center

Journal of the American Medical Association

The new study, published today in The Journal of the American Medical Association, found that patients taking Depakote were 2.7 times as likely to kill themselves as those taking lithium. Earlier studies by others had also found that lithium could prevent suicide, but today’s report is the first to compare suicide and attempted suicide rates in lithium and Depakote users. The study was based on medical records of 20,638 patients aged 14 and older in Washington State and California who were treated from 1994 to 2001.

Lithium, an old and inexpensive drug that has fallen out of favor with many psychiatrists, is better than the most commonly prescribed drug, Depakote, at preventing suicide in people who have manic-depressive illness, researchers are reporting.

People with the illness, also called bipolar disorder, swing back and forth between bleak spells of depression and periods of high excitability that may run the gamut from euphoria to rage. From 1.3 percent to 1.5 percent of people in the United States suffer from bipolar disorder, and their risk of committing suicide is estimated to be 10 to 20 times that of the rest of the population.

Perhaps because patients are more likely to seek medical help when they are depressed than when they are manic, the disorder is often misdiagnosed at first as depression alone, but antidepressants are not the correct treatment for bipolar disorder and may in fact make it worse.

The new study, published today in The Journal of the American Medical Association, found that patients taking Depakote were 2.7 times as likely to kill themselves as those taking lithium. Earlier studies by others had also found that lithium could prevent suicide, but today’s report is the first to compare suicide and attempted suicide rates in lithium and Depakote users. The study was based on medical records of 20,638 patients aged 14 and older in Washington State and California who were treated from 1994 to 2001.

Solvay Pharmaceuticals, a maker of lithium, paid for the study, but did not influence the findings or the way they were reported, the authors said.

The study included 53 actual suicides and 383 attempted suicides that led to hospitalization. But the researchers, as well as Depakote’s manufacturer, cautioned that because this study was based only on patients’ records, it was not conclusive.

Precisely how lithium might prevent suicide is not known, although it is believed to help regulate levels of serotonin, a brain chemical that influences mood.

“Lithium is clearly being underutilized,” said Dr. Frederick K. Goodwin, the senior author of the study and director of the psychopharmacology research center at George Washington University Medical Center. The drug can save lives, he said, adding, “The real tragedy is that a lot of young psychiatrists have never learned to use lithium.”

Lithium, which can smooth out the highs and the lows of bipolar disorder, was first used in the 1950’s, and in the 1970’s was the first drug to be designated a “mood stabilizer” by the Food and Drug Administration. But the drug has been around for so long that its patent has expired and generic versions exist, meaning that lithium cannot generate substantial earnings for industry, Dr. Goodwin said. Drug companies promote newer, more profitable drugs like Depakote.

Some difficult cases referred to Dr. Goodwin turn out to be people who have never taken lithium because their psychiatrists, often under 40, never thought of prescribing it. But Dr. Goodwin also emphasized that lithium did not work for everyone and that other drugs like Depakote were also needed.

Dr. John Leonard, a spokesman for Abbott Laboratories, the maker of Depakote, questioned the findings. Dr. Leonard said that studies looking back at patients’ records were inherently flawed and not as reliable as studies in which patients were randomly assigned by researchers to take one drug or the other. He said conclusions could not be drawn from the data, and doctors should not base treatment decisions on it.


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I Survived A Cocktail of Anti-depressants and Dexedrine

I progressed to severe suicidal feelings.”

 

I thought I was maintaining well on Welbutrin and Dexedrine. While later researching overdose effects of anti-depressants, I realized that my doctor was balancing overdose effects of both medicines by raising one or the other. When a family trauma occurred that caused me to feel threatened for the well being of my children, my “mama hormones” took effect and caused an aggressed state that surged during PMS.

I was “protecting” my children from their own father who wouldn’t keep the perpetrators away from the home (his family). I progressed to severe suicidal feelings. My Doctor still yet knowing of this tried to prescribe sleeping pills to help with my sleeplessness. Even though I had never acted out suicide (the fear of not succeeding throughout my ordeal sustained me), I was afraid of these pills because the consequence was less severe than scarring my skin or breaking my spine.

Unfortunately while in a fight with the father of my children, after throwing glass glasses into the wall, in a fit of despair of the damage I realized I was doing with this relationship and my children’s emotional well being, I picked up a piece of glass and tried to slit my wrist. My first ever attempt at suicide.

I started counseling with a counselor of the same clinic at another location. My doctor at my third month appointment after this episode, changed my prescription to Prozac as well as the Dexedrine. Was still trying to give me sleeping pills because I had resorted to Marijuana (one of my recovered addictions broken) to help me relax enough to sleep. She was aware of this ASAP after I started.

So the change was done with this awareness. I started to notice symptoms of what I felt was ADHD (this doctor had diagnosed me after numerous drug therapies as Severe Depression/ADHD though I was not hyperactive). When I called to complain of symptoms, she tried to raise the dosage of the Prozac. I complained that the symptoms were of ADHD, so felt that the other should have been raised.

She conceded without a closer follow up appointment. At my PMS – I experienced a psychotic episode in one of my suicidal states of taking my children’s perpetrator (a minor) and his family at their home and killing them and my self with the media there because I was upset at the system for not intervening with this young person when he needed help (this person is also a victim of Prozac and Ritalin introduced at nine years of age which caused anger outbursts that didn’t stop with the medicine being stopped).

But unsafe people abound on both sides of the families and all I could think was who would be at the funerals consoling my children. This also kept me from acting out aggression and getting myself put into jail. I slept three hours or less a night. I was “driven”.

My Doctor’s nurse kept canceling my appointments a month at a time. After the third cancellation, I started to get upset. I had an episode after being late for the third appointment with a nurse that was cancelled because I got lost in the bus system. I walked in and was refused to be seen. After arguing with the receptionist, I stormed off and “popped” open a solid oak door that slammed into the wall and walked close to six miles in the heat of the day (I live in Texas) before I called my children’s father to pick me up.

The break in the car rejuvenated me to stay up still yet to another three hours sleep. I was also in a PMS state. I finally got through to the office management (a nurse and receptionist was intercepting me from reaching them) whereas this doctor soon left and personnel was cycled out. I started with a new Doctor in the same office that my counselor was at that was newly hired with this clinic. He withdrew me from the Prozac and started me on Neurontin first.

It seemed to aggress me more. I would be doing dishes and feel a bubble of suicide feelings surface without provocation of trauma. Tegretol pretty much the same. When he wanted to try Depakote I couldn’t the first time because I would go into tears from fear. I tried it finally after the second time and it had the same effect as Neurontin. Finally he used Topamax. –-12 hours –- I neutralized.

Unfortunately though it made me oversensitive to trauma, most particularly trauma associated to childhood trauma. I’ve since discovered that symptoms I had been describing to the first Doctor was of PTSD. I had memories from my childhood surface after the death of an adult mentor that I had repressed. I overreacted from trauma with withdrawal and weeping episodes. Again unfortunately, I started to recognize the patterns starting with Phil Hartman’s wife and the mass murder/suicides to my psychotic episode and started to outcry. I cried at work (which I’m still suffering from the consequences of). I cried to my Doctor of twenty years (who at my last appointment had security guards in the lobby)

I cried to my daughter’s school when I associated this teacher’s grabbing my daughter in the face and raging at her to a probable connection of my same scenario because her children were diagnosed as ADHD and she was sure she had ADD. No one could understand that I was out crying a past state. A lady at work told me of road rage with a near miss with her son in the car and she chased this little old lady down the road and if she had been able to have stopped this lady she would have literally killed her. She was on Zoloft. The clinic I was at was having a lawsuit filed against them from the husband of a lady who begged to be institutionalized and was refused whereas she committed suicide.

This lawyer refused to represent me. I started to realize after several calls to several lawyers that that was a strike against me, still being alive. I was a risk. My Doctor leveled me off the Topamax by lowering the dosage when I would feel the aggressed state start to impose to where I am totally off of all the drugs. I am exactly where I was before I started to take all of the medications. I have PTSD with severe depression. I have suffered from the symptoms all but the six years with the attempt for help, with these symptoms. My son was on Ritalin, then Dexedrine. His pediatrician had been regulating his dosage which was extremely high. I’ve taken him off of the medication, but because of his obvious failing grades, I’m getting extreme pressure from his teachers. I’m still in recovery, this family is still in recovery and have yet a break for a real breather from our ordeal.

My daughter’s school is trying to get me to take her to get diagnosed as ADD when she’s suffering from trauma reactions from her prior teacher. I have refused and have had insinuations of being a bad parent. All I could do was sit there near tears and make the comment “You have to sit in my chair to understand why I feel the way I do”. I researched the medicines based on the Topamax Anti Epileptic drug in my college Psychology book and discovered the Limbic System. The Amygdala and the Hippocampus hadn’t even had a real name in that book, but it described a part of the brain that if one side were disabled, the monkey subject would show severe aggression at the slightest provocation, and severe docileness when the other part was disabled. I ironically identified with that. Prozac/Dexedrine and Topamax.

I theorized that the Dexedrine blocks of Trauma Reactions that makes you pull back from fire when the fingers are burned. Which in the evolution of infant to adult progression can get stuck like a scratched record when trauma occurs – the variables differing in intensity and level of cognitive ability and recovery depending on completion of assimilation of the trauma (if at all) at the level of the cognitive ability when the trauma occurred. If I had been withdrawing publicly from drug addiction (which I have withdrawn from all my addictions privately), I would have received more support than what I received from what I was prescribed. It also concerned me that I was more accepted while I was in my aggressed state than the traumatized state crying. I had been raging with my family for two years.

I realized I was out of control, I took responsibility for the consequences. I worked to keep the responsibility of my actions when it concerned my children so that they could at least not be made to think they were responsible for my severe reactions. I took my daughter to a counseling appointment of mine so that I could get help in interaction with her. Both of my children had their counselor to help balance against me. I called the police on myself when my children’s father and I had gotten physically violent the second time within a six-month span in a fifteen-year relationship because I was afraid of losing control. One of the Police Officer’s told me he was on Prozac. No one listened to me. Until I became traumatized from the realization to where my children and their father had been for two years.

Than I was a threat because I vocalized my trauma. I worked with animals as a teenager – Domestic and Feral. I watched all the nature shows. I could fit the scenarios across the nation to the Wonders of Animal Behaviour. “Instinct”. Hormonal/Chemical urging of nesting instincts male/female. Territorial instincts. Abortion of young and newborn infants because of the inhospitable and contaminating environment. That’s my story. I never did as much damage with my own addictions as was done to me from a professional’s prescription of our society’s addiction. We have “red dyed” Limbic System’s out their waiting for the introduction of drug addiction, of ignorant and sloppy professionals mixing unmixable drugs, ready to pop out there like powder kegs. I grant permission to publish anonymously my story.

Thank you for this outlet and validation

(Withheld on request)

11/22/1999

This is Survivor Story number 28.
Total number of stories in current database is 96

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