LA Times: Paxil (Brisdelle) Promotes Breast Cancer



The following is my comment in the LA Times addressing this new research:

“Little surprise this is when we knew years ago research indicated a SEVEN times greater chance of breast cancer with Paxil. But unknown to me when I saw the approval come through for Brisdelle this summer is that it was actually Paxil renamed!! Surprising? You bet! Because I have been one of the most outspoken opponents to antidepressants for 25 years, writing, lecturing, doing media interviews even with the LA Times & not even I knew the FDA was approving Paxil!

“There is no excuse for this!!! Why was Lilly allowed to change the name of Prozac to Sarafem to prescribe for PMDD & Wellbutrin allowed to change its name to Zyban to prescribe for smoking cessation? Anyone wonder what they are trying to hide? Feel free to go to our international support site to find out

“Patients need to know the type of drug they are taking! When prescribed an antidepressant they need to know what it is! When I did the Leeza Gibbons Show on the subject of mothers on antidepressants killing their own children we were told we could say the word “antidepressant,” but we could not say the brand names of the medications because of their advertisers. So with them peddling these drugs under another name & for different health issues, how does the patient know they are taking an antidepressant? With antidepressant side effects as deadly as homicidal & suicidal ideation this is criminal!”

I personally have lost two close friends to Paxil-induced breast cancer although one got cancer on her ear due to her use of Prozac first. Remember that all SSRIs work basically the same way and should have very similar effects. And my uncle, who had refused to even allow me to discuss antidepressants with him, died of a very fast moving cancer due to his use of Paxil. He was diagnosed with inoperable cancer on Thursday and by the following Wednesday he was dead. In my last conversation with him a day or two before his death as we said our goodbyes he said, “I know I have given you a LOT of flack about what you are doing concerning these drugs, but DON’T YOU EVER STOP because what has been done to me should be done to no one!”

This is why I am so firm in discussing what needs to be done even after coming off these medications. The damage they have caused needs to be addressed and alternatives used to rebuild in order to avoid cancer and many other serious health problems due to the post drug adverse effects of the antidepressants. If the deficit is not addressed that the drug leaves in its wake problems can arise. I am working with a young woman currently who now has breast cancer years after her use of Prozac. Just a coincidence? I do not believe it is. She has had no opportunity to rebuild after being incarcerated at age 13 due to the drug effects. So when I post information on alternative treatments for cancer you can see why I feel it is important to pay attention.

Be sure to read the full report in the original LA Times news article and video:,0,3273056.story#ixzz2toBYBJf9

Ann Blake Tracy, Executive Director,
International Coalition for Drug Awareness &
Author: ”Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”

WITHDRAWAL HELP: You can find the hour and a half long CD on safe and effective withdrawal helps here:  And if you need additional consultations with Ann Blake-Tracy, you can book one at or sign up for one of the memberships for the International Coalition for Drug Awareness which includes free consultations as one of the benefits of that particular membership plan.

WITHDRAWAL WARNING: In sharing this information about adverse reactions to antidepressants I always recommend that you also give reference to my CD on safe withdrawal, Help! I Can’t Get Off My Antidepressant!, so that we do not have more people dropping off these drugs too quickly – a move which I have warned from the beginning can be even more dangerous than staying on the drugs!



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“…the information about Paxil explained why I should have gotten two tumors in the same year.”

In 2001, I had breast cancer twice!! My mammogram on 2/28/01 showed a tumor in one breast and a questionable area in the other. I had a lumpectomy for the first tumor ( invasive ductal carcinoma), and, seven months later (after a second mammogram and biopsy), a second lumpectomy for the second tumor ( mucinous invasive ductal carcinoma.)

It was when I was reading PROZAC: PANACEA OR PANDORA? in the summer of 2002 that I learned that a couple of small studies had linked Paxil to breast cancer. I had taken Paxil for seven months, from 11/99 to 6/00, to see whether it would help a migraine problem that has plagued me for many years. My dose was small, and if not for Dr. Tracy’s book I never would have made the connection with my cancers. Yet for me, the information about Paxil explained why I should have gotten two tumors in the same year. (I had had breast cancer once before, in 1971, and had had a lumpectomy at that time, when it was a very controversial procedure. I had been squeaky clean since then — until the new tumors in 2001.)

I am posting this because the connection between an SSRI and a tumor first seen some eight months later isn’t as obvious as some other drug side effects people experience. However, I want to suggest that readers of this message board stay on the alert for this kind of connection. I believe Dr. Tracy says that other SSRI’s could cause cell proliferation as well — but the studies I know about are on Paxil, and that was the drug I took. I am also posting and ADR notice to the FDA.

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6/28/2000 – Antidepressant medication use and breast cancer risk

As most of you have already read in my book, Dr. Lorne Brandes linked
antidepressants to cancer in a 1992 study. Now we have additional evidence
that this is happening with one of the leading cancer killers in women –
breast cancer. This study indicates that long term use is the biggest culprit
in breast cancer with 2 years of use of the older tricyclic antidepressants ev
en doubling the rate of cancers and Paxil showing a substantial increase as
well. “Use of tricyclic medications for greater than 2 years, however, may be
associated with a twofold elevation, and use of paroxetine [Paxil] may be
associated with a substantial increase in breast cancer risk.”

We are always grateful to have any of you update us on important issues such
as this so that we can notify others. A special thank you goes out to our
Norwegian director, Svein Reseland, for updating us on this study and for the
assistance he has contributed over the years. It is a pleasure to work with

Ann Blake-Tracy, Executive Director,
International Coalition For Drug Awareness

Am J Epidemiol 2000 May 15;151(10):951-7 Related Articles, Books

Antidepressant medication use and breast cancer risk.

Cotterchio M, Kreiger N, Darlington G, Steingart A

Division of Preventive Oncology, Cancer Care Ontario, Toronto, Canada.

[Medline record in process]

Experimental and epidemiologic studies suggest that antidepressant medication
use may be associated with breast cancer risk. This hypothesis was
investigated using a population-based case-control study; cases diagnosed in
1995-1996 were identified using the Ontario Cancer Registry, and controls
were randomly sampled from an Ontario Ministry of Finance database. Data were
collected using a self-administered questionnaire, and multivariate logistic
regression was used to estimate odds ratios and 95% confidence intervals.
Adjusted odds ratio estimates ranged from 0.7 to 0.8 and were not
statistically significant for “ever” use of antidepressants, tricyclics, and
selective serotonin reuptake inhibitors. Compared with no antidepressant use,
use of tricyclic antidepressants for greater than 2 years’ duration was
associated with an elevated risk of breast cancer (odds ratio (OR) = 2.1, 95%
confidence interval (CI): 0.9, 5.0). Of the six most commonly reported
antidepressant medications, only paroxetine use was associated with an
increase in breast cancer risk (OR = 7.2, 95% CI: 0.9, 58.3). Results from
this study do not support the hypothesis that “ever” use of any
antidepressant medications is associated with breast cancer risk. Use of
tricyclic medications for greater than 2 years, however, may be associated
with a twofold elevation, and use of paroxetine may be associated with a
substantial increase in breast cancer risk.

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5/7/2000 – Drugmaker: Breast Cancer Drug Linked to Death

Adverse Reaction
Drugmaker: Breast Cancer Drug Linked to Death

By Jessie Seyfer
The Associated Press

S A N F R A N C I S C O, May 5 — Pharmaceutical maker
Genentech Inc. has warned doctors that the breast cancer drug
Herceptin is linked to 15 deaths and 47 other adverse reactions
in patients.

In a letter to doctors sent Thursday, the company said the
adverse effects included allergic shock and extreme respiratory

“We sent the letter to oncologists to heighten their awareness
and educate them about infrequent adverse events that can
occur in certain patients,” Genentech spokesman Neil Cohen

An estimated 23,000 patients have been treated with Herceptin.

Severe Reactions
Severe reactions to Herceptin had not occurred in clinical trials
before the drug gained Food and Drug Administration approval
in 1998, Cohen said.

But sometimes reactions can’t be foreseen in trials, he said.

“A lot of times you might see some safety issues once the drug
gets put into a larger patient population,” Cohen said.

Cohen said he didn’t know when the company first heard of the
deaths and reactions, but analysis had confirmed the link to

Symptoms Seen Within 24 Hours
In nine of the 15 deaths, symptoms arose within 24 hours of the
time Herceptin was administered, according to the letter.

Genentech is working with the FDA to have the drug’s label
amended to reflect the new risks, Cohen said.

Herceptin is used to treat breast cancer patients that have too
many copies of the HER2 gene. A healthy version of this gene
produces a protein that signals cells to grow and multiply
normally. But in women with too much HER2, the breast cells
reproduce out of control and spread throughout the body.
Herceptin, an antibody, blocks excess HER2, shrinking and
eliminating tumors.

Copyright 2000 The Associated Press. All rights reserved. This
material may not be published, broadcast, rewritten or

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