PLEASE HELP US GET SOME CRITICAL INFORMATION OUT TO THE PUBLIC

Mark Taylor
MARK ALLEN TAYLOR

(FIRST BOY SHOT AT COLUMBINE HIGH)

 

At the International Coalition for Drug Awareness we have been in the process of putting together some very critical information on antidepressants and school shootings and other acts of violence for the Columbine anniversary and we need your help. For over two decades I have worked to fund by myself most all of what we have done in the raising awareness of the dangers of antidepressants (mortgaging my own home multiple times and putting the funds from our materials back into this). But after a couple of decades at this point I do not have any funding to help when we now need to gather some of the most critical information yet – information that should REALLY help to wake up society. So I am asking for help from all of you to help us do that.

We have been informed that to get this information it is going to cost us between $400 – $600. Any of you who can help us in any way we urgently need your help! This is because we need to get the information BEFORE the Columbine anniversary on April 20 to get media attention from that. (I am sorry because of the late notice. It took me some time to track this information down and I would have sent this request out much sooner had it not been for the terrible accident my brother suffered last week – thank you for the prayers as they have produced miracles but things are still extremely critical.)

Please help if you can! Any amount so that we can get this done will be GREATLY appreciated and this information will be shared with the world. Much of this information most have been unaware of before and this will bring it to public light. I firmly believe it will make a BIG difference in this battle we are waging for truth about these drugs. I know you will be excited to share this as soon as we get it. PLEASE go to our website to make your donation now:

http://www.drugawareness.org/contact/support-the-site

Then watch over the next couple of weeks for this explosive information to begin to be posted from our DrugAwareness.org site!

Thank you!

Ann Blake Tracy, Executive Director,  International Coalition for Drug Awareness www.drugawareness.org & http://ssristories.drugawareness.org  Author: *”Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”




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10 YEARS AFTER BOWLING FOR COLUMBINE-MY RESPONSE TO MICHAEL MOORE

BowlingForColumbine

WHERE ARE WE 10 YEARS AFTER???

Michael Moore is asking everyone this Saturday to hold their own 10 year anniversary party of the opening of his movie Bowling for Columbine which of course blamed guns for the massacre at Columbine High School. But in the movie I did with him, The Drugging of Our Children (http://www.drugawareness.org/videos/the-drugging-of-our-children), he said all those reasons they came up with in his movie for the reason Columbine happened were BS. (Michael’s direct quote: http://www.drugawareness.org/articles/michael-moore-cause-of-columbine)

Yet now he is using his movie once again to promote gun control instead of taking the opportunity to give the world answers to what really is causing all these school shootings???? Why?

He should take the opportunity to tell the world the truth if he has the stage now to do that.

I encourage all of you to hold your own 10 year anniversary of Bowling for Columbine and use the following information I just wrote in a letter to Michael Moore to set the world straight on what REALLY happened at Columbine and the large majority of other school shootings!!! Watch Gary Null’s The Drugging of Our Children instead.

PLEASE SHARE THIS EVERYWHERE: your local news, internet, Facebook, radio, television, etc. There is no excuse for this “BS” as Michael called it to continue to be spread around since Pharma gives us enough BS on your nightly television about antidepressants to cover the planet!!

Ann Blake Tracy, Executive Director,

International Coalition for Drug Awareness
www.drugawareness.org & http://ssristories.drugawareness.org

Author: Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”

 

MY LETTER TO MICHAEL MOORE

“Michael I would be more than happy to join you on that panel March 23, but have not received my invitation. Yet as you know I have been tracking the school shootings and testifying in those cases more than any one individual I know of worldwide.

MICHAEL MOORE SAYS ALL CAUSES GIVEN FOR COLUMBINE IN HIS MOVIE WERE BS

“When you and I did the movie together, The Drugging Of Our Children by Gary Null, after you read my book, Prozac: Panacea or Pandora?, you CLEARLY stated that ALL the reasons you looked at in your movie Bowling for Columbine as the cause for the tragedy were BS.

You went on to say that the only reason that made any sense for this violence were the antidepressants given to these kids. Your direct quote: http://www.drugawareness.org/articles/michael-moore-cause-of-columbine

ANTIDEPRESSANTS HAVE WARNINGS FOR SUICIDE AND HOMICIDE

“Antidepressants have warnings for both suicidal and homicidal ideation and the FDA warnings indicate those reactions to be at almost double the rate for those under the age of 25. That is not just killing yourself or someone else but having persistant ruminating thoughts of both suicide and homicide, along with the same persistant thoughts of various methods of killing – thoughts Eric complained of within only weeks after first being placed on Zoloft. Putting a gun in his hand is NOT what produced those thoughts, but a drug did, and the drugs even carry a warning that they can produce that!!

With only me and a couple of others working to gather these cases over the past two decades out of 70 school shootings we have had 68 school shooters on antidepressants … you know this has to be only the tip of the iceberg. Seems pretty simple math at this point! List of shootings & meds: http://www.drugawareness.org/ssri-nightmares/school-shootings And here is the same list of school shootings in a video version: http://www.youtube.com/watch?v=JpFoivbZH1o&feature=player_embedded

IT IS NOT THE GUNS, IT IS THE ANTIDEPRESSANTS!

“It is NOT the guns! It is the drugs! If they do not reach for guns, they reach for knives, hammers, hatchets, bows and arrows, bombs, fire, poison … anything imaginable. The compulsion to kill is overwhelming when produced by these drugs.

“You have the knowledge now Michael and are in the position to do something to set this straight. I hope you have the integrity to do so. Lives are at stake…so many lives that I cannot even begin to keep up with the tragedies that flood in daily! Those who died at Sandy Hook are FAR FROM ALONE! The death toll in these other cases may not be quite as high in each individual case, but when there are so many of them, the accumulating death toll is astounding.

TAKING ON THE NRA OR PHARMA?

“Taking on the NRA is like taking on a kitten in comparrison to taking on Pharma as Columbine victim Mark Taylor in your movie Bowling for Columbine has done. He was the only one who did not back down from them when warned by the drug company what would happen if anyone dared to sue them. http://www.drugawareness.org/recentcasesblog/school-shooter-victim-join-forces

“Do you know where he is now Michael? Do you know what payback can be like when you really go after the Big Boys? Maybe you need to call me for an update because it is NOT pretty!”

A SCHOOL SHOOTER SPEAKS OUT – WHY I TOOK A GUN TO SCHOOL…

And here is the only school shooter to speak out I am aware of telling his own experience to help us understand what is causing school shootings:

http://www.drugawareness.org/recentcasesblog/why-i-took-a-gun-to-school-1

About the Author: Ann Blake Tracy is the author of PROZAC: PANACEA OR PANDORA? –OUR SEROTONIN NIGHTMARE! , and the director of the International Coalition For Drug Awareness [www.drugawareness.org]. She has testified before the FDA and has testified as an expert in legal cases involving serotonergic medications since 1992.

BOOK: Prozac: Panacea or Pandora? – Our Serotonin Nightmare! Anything you ever wanted to know about antidepressants is there along with everything drug companies hope you never find out about these drugs.

Available at: http://www.drugawareness.org/shop/books/prozac-panacea-or-pandora

SAFE WITHDRAWAL CD “Help! I Can’t Get Off My Antidepressant!” on how to safely withdraw from antidepressants & most psychiatric medications is saving lives helping those stuck on antidepressants to know how to safely withdraw.

Available via download at: http://www.drugawareness.org/shop/audio/help-i-cant-get-off-my-antidepressant-mp3-download

Or available by CD at: http://www.drugawareness.org/shop/cds/help-i-cant-get-off-my-antidepressant

 

BOOK TESTIMONIALS:

“Very bold & informative”

“Priceless information that is giving me back to me”

“The absolute best reference for antidepressant drugs”

“Well documented & scientifically researched”

““I was stunned at the amount of research Ann Tracy has done on this subject. Few researchers go to as much trouble aggressively gathering information on the adverse reactions of Prozac, Zoloft and other SSRIs.”

WITHDRAWAL HELP CD TESTIMONIALS:

“Ann, I just wanted to let you know from the bottom of my heart how grateful I am God placed you in my life. I am now down to less than 2 mg on my Cymbalta and I have never felt better. I am finally getting my life back. I can feel again and colors have never been brighter. Thanks for all that you do!!” … Amber Weber

“Used your method of weaning off of SSRI’s and applied it to Ambien. Took 6 months but had been on 15 mg for years so what was another 6 months. I have been sleeping without it for 2 weeks and it is the first time I have been able to sleep drug free for 15 years. What a relief to be able to lay down and sleep when I need or want to. Ambien may be necessary for people at times but doctors giving a months worth of it at a time with unlimited refills is a prescription for disaster. It is so damn easy to become dependent on. Thanks for your council Ann.”… Mark Hill

“I’m so thankful for AnnTracy and all her work. Also for taking the time out to talk to me and educate everyone! She has been a blessing to me during this awful time of antidepressant hell!” … Antoinette Beck

I just have to put this out there… I just finished listening to the Ann Blake-Tracy’ s talk about getting off antidepressants. I cannot even begin to explain how grateful I am for the information provided! Not only for my son but myself, I have suffered terrible migraines from muscle stiffness, teeth grinding and difficulty sleeping and guess what… I was put on Zoloft for MILD postpartum depression almost 5 years ago. I was told it was better to just stay on it while pregnant with my 3rd child and then for awhile after, just for precaution, after all I was having no side effects and it is safe. My youngest in now 2. While my gut told me it was wrong for my son to be medicated I never considered this was the cause for my own pain that seems to be worsening. I guess the drug had just become part of my routine because of being on it for so long. Now we will wean off together. The information given here is so valuable and life changing. Once again….Thank you!…Amanda Briar

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ANTIDEPRESSANT-INDUCED VIOLENCE LEADING US TO GUN CONTROL & COMING RELEASE OF VIDEO OF SCHOOL SHOOTER & FATHER TELLING THEIR STORY – REM SLEEP BEHAVIOR DISORDER PLAYS A ROLE IN SCHOOL SHOOTINGS

Adam Lanza

ANTIDEPRESSANT-INDUCED VIOLENCE LEADING US TO GUN CONTROL

ANTIDEPRESSANTS??? Although we have not yet learned what school shooter Adam Lanza was taking we do know he had a diagnosis of Aspergers  for which antidepressants are prescribed as a standard treatment by the large majority of physicians.  (If you will recall the young man who was involved in the violence with a bow & arrow that left three dead in Casper, WY the week before had also been diagnosed with Aspergers meaning it was also likely he too was taking antidepressants or recently had taken them because this can happen in withdrawal from the drugs if withdrawn too rapidly.) And I stated when this Portland mall shooting happened a week or so ago that this case clearly appeared to be antidepressant-induced as well. But when you consider the outcome in this case as opposed to the shooting at the school last Friday you can see why it is not being mentioned by those wanting to point their fingers at more gun control. There would have been far more deaths in this incident had this mall customer not have had a gun permit.

MY TOMBSTONE HISTORY

Before I began to research antidepressants I was very much anti-gun even though my great great grandfather was Mayor of Tombstone, Arizona during one of the most violent periods – the OK Coral Days. Wyatt Earp was his sheriff & Johnny Ringo was his friend and one day he had to stand between them to stop a gun battle. But my kids will tell you I refused to even allow toy guns in our home. But now AFTER learning about these drugs and interviewing so many who have had adverse reactions involving violence with any type of weapon my views have changed completely.

SHOOTER’S DESIRE TO DIE RATHER THAN HARM ANOTHER

Why? Because everyone of them has made the statement that they wish someone would have stopped them (with a bullet if necessary) from doing what they did while having this toxic reaction that led them to such out of character violence where they could not stop themselves and yet did not want anyone hurt. Do I believe those feelings were any different for the school shooters from Eric Harris & Dylan Kleebold to Adam Lanza? NO!!! I have always said that they would have been the ones most shocked by their own actions as they reached the other side and were able to realize what they had done because of these deadly drugs.

EEERIE PROPHESY OR SIMPLE MATH?

In fact in 1992 I contacted the NRA and told them that if they did not help to educate the public about antidepressants that these drugs would be the means by which enough violence would errupt in our society for those in power to call for the taking of America’s guns. Apparently 20 years ago I was the only one to see this coming and was not taken seriously. Now here we sit right in the middle of it all…

Ann Blake Tracy, Executive Director,
International Coalition for Drug Awareness
www.drugawareness.org & www.ssristories.drugawareness.org
Author Prozac: Panacea or Pandora? – Our Serotonin
Nightmare! & safe withdrawal CD Help! I Can’t Get
Off My Antidepressant!

PS If sharing this link please include my statement with it.

www.youtube.com/watch?v=BuLgO4wo4xI&feature=youtube_gdata_player

 

“INSIDE THE BROKEN MIND & DAMAGED SOUL OF ADAM LANZA”… (ABC)

LEARN HOW REM SLEEP BEHAVIOR DISORDER PLAYS A ROLE IN SCHOOL SHOOTINGS

What patients on antidepressants and their families are not being told and desperately need to be warned of is the REM Sleep Behavior Disorder which is basically where patients act out nightmares. Considering the time of day this shooting happened that could easily have been what happened to this young man. That is a condition where you act out your nightmares. Restless leg syndrome is often the first sign of this developing in a patient. another sign is very vivid dreams. of those being diagnosed with this extremely dangerous sleep disorder 86% are taking an antidepressant making these drugs the most common denominator.

SCHOOL SHOOTER & HIS FATHER SPEAK OUT

I will soon be posting an interview with another young man who was on antidepressants when he took a gun to school just over a decade ago. You will be able to clearly see that what he describes is a REM Sleep Behaviour disorder reaction steming from a switch from Paxil to Efffexor. This is exactly what comedian Phil Hartman’s wife suffered when she shot him and herself while under the influence of Zoloft.

This disorder often begins to manifest via Restless Leg Syndrome or very vivid dreams or nightmares. Watching for those reactions to antidepressants is most critical. I will have a new e-book published on this very deadly reaction in the next week or so. Corey’s father is also making himself available for interviews.

WATCH FOR POSTING SOON

Be sure to follow me on Facebook (Ann Blake-Tracy or International Coalition for Drug Awareness) or watch for the video posting on our website at www.drugawareness.org. All the families who lost loved ones in this recent tragedy need to see this to understand the reaasons behind the nightmare they have just experienced. And all antidepressant users need to watch this video with Corey as well.

Here is a news clip to introduce you to Corey along with Mark Taylor, who was the first boy shot at Columbine High School:

School Victim & School Shooter Join Forces to Stop Shootings

www.drugawareness.org/recentcasesblog/school-shooter-victim-join-forces

Also of interest….Michael Moore, Producer of the Movie Bowling for Columbine, Together They Are Speaking Out About Antidepressants Being the Cause for Columbine Massacre, NOT GUNS!!!!

www.drugawareness.org/articles/michael-moore-cause-of-columbine

Ann Blake Tracy, Executive Director,
International Coalition for Drug Awareness
www.drugawareness.org & www.ssristories.drugawareness.org
Author of Prozac: Panacea or Pandora? – Our
Serotonin Nightmare & safe withdrawal CD “Help!
I Can’t Get Off My Antidepressant!”

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ANTIDEPRESSANT: SIX DEAD: DAMIAN RZESZOWSKI NOT GUILTY IN MASS MURDER CASE

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This beautiful little girl is Kinga Rzeszowski (5) who was stabbed to death along with her mother, younger brother, maternal grandfather, friend & her friend’s mother by her father who then stabbed himself 40 times even to the point of collapsing one of his lungs, then slashed his throat & wrists another 20 times! A jury in the UK has just found him not guilty of murder, but guilt of the lesser charge of manslaughter. A day or two before the murder he had overdosed on antidepressants. Few realize that as the serotonin rises you have an LSD or PCP reaction because the body reacts to LSD or PCP as a rush of serotonin. They mimic serotonin. There is little difference when antidepressants force the serotonin level too high! Would anyone have been surprised by his actions had he been taking PCP? Of course not! But they remain CLUELESS when it comes to this similar effect with antidepressants!!! So clueless that he continues taking a cocktail of drugs in prison – a common theme in these antidepressant-induced tragedies.

After two decades of testifying & consulting in these antidepressant-induced violent murders & suicides it amazes me how absolutely ignorant the entire world remains, including the court system, to the connection & true cause of such incomprehensible violence!!! I have worked Columbine & MANY other US school shootings, comedian Phil Hartman & his wife’s murder/suicide & MANY more murder/suicides wiping out entire families, Andrea Yates’ case & MANY other mothers who have killed their children over the past 20+ years. Yet the courts & everyone else seem to continue to remain ignorant of the fact that antidepressants cause you to act out your worst nightmare in a sleep state called a REM Sleep Behavior Disorder (RBD). Of those being diagnosed with RBD 80% hurt themselves or someone else & 86% of those diagnosed with RBD were found to be taking an antidepressant. It antidepressant is the single most common denominator in these cases, yet it seems the whole world is failing the simple math in this case!

How do the pharmaceutical companies keep these cases suppressed the way they do?! They have LONG known their drugs cause these tragedies. The large numbers of secret settlements remain hidden from the public so you are not aware how often they happen. Goggle ssristories to see a database of just a few all too similar cases. (Especailly note the Donald Schell case in Wyoming) So WHO is guilty of premeditation in this case? Do you really think Damian Rzeszowski was warned that taking an antidepressant could possibly cause this? NO! And few other patients have ever been warned either!

You can continue to cry for vengeance upon this man or any of the others instead of looking at the true guilty parties in this horrific tragedy, but mark my words … in doing so the cost may be your life or the life of a loved one someday soon.! This is a serious public safety issue! When is someone near you on an antidepressant going to slip into a toxic nightmare (literal nightmare of RBD) & include you in that nightmare?

Look how many times this man stabbed himself! even to the point of collapsing his lung! That cannot happen without this frenzied drug state! He had just overdosed on these drugs. Tragically, few are aware that the brain goes dead before the body in an overdose with antidepressants. Why was he released from the hospital before the full toxic effect of the rising serotonin hit him to cause this psychotic reaction?

WARNING: If you are taking an antidepressant you must know that it is more likely that this violent sleep disorder, RBD, is more common in withdrawal .So, weaning off an antidepressant MUST be VERY, VERY gradual (months or years, rather than days or weeks) so as to avoid this serious toxic reaction.

http://www.ssristories.drugawareness.org/show.php?item=5087

http://www.independent.ie/world-news/europe/video-husband-guilty-of-killing-six-in-barbecue-rampage-3209635.html

http://ssristories.drugawareness.org/archive/show.php?item=240

Ann Blake-Tracy, Executive Director,
International Coalition for Drug Awareness

www.drugawareness.org & www.ssristories.drugawareness.org
Author: *”Prozac: Panacea or Pandora? – Our Serotonin Nightmare –
The Complete Truth of the Full Impact of Antidepressants Upon Us &
Our World”* & Withdrawal CD *”Help! I Can’t Get Off My Antidepressant!”

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FDA WHISTLEBLOWER SPEAKS OUT – THINK YOU HAVE DRUG SAFETY? BETTER THINK AGAIN!!

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Prescription drugs, taken as prescribed (according to FDA guidelines), are the third leading cause of death in American (according to THEIR figures which could easily be tampered with to keep the figures lower than what they really are). This article will help you to see why we are seeing such a large number of deaths as a result of the FDA’s policies.

Another FDA whistleblower has stepped forward, and what he has to say about the agency’s drug safety reviews is shocking even to the jaded reports my friend Dr. Joesph Mercola. This article is an alarming wake up call for those who have been under the assumption that the FDA has the public safety in mind & is busy protecting our health & safety.

Learn how the FDA bypassed or ignored safety issues on major drug approvals from Ronald Kavanagh, who was a drug reviewer for the FDA in the Center for Drug Evaluation and Research from 1998 to 2008
He reveals some of the internal rules of the FDA that are clearly designed to thwart serious safety reviews from the get-go, and other loopholes frequently used by drug companies to circumvent safety investigations
Five years ago, a Subcommittee on Science and Technology report entitled “FDA Science and Mission at Risk” detailed how the FDA cannot fulfill its mission, in part because its scientific base has eroded and its scientific organizational structure is weak
The subcommittee concluded the FDA’s failures place the health of Americans and the financial health of the nation at grave risk

On September 13, 2004 Mark Taylor, the first boy shot at Columbine High School, stood before the FDA and asked them where their protection was the day he and his classmates were shot. He then told them that if they had been doing their jobs Columbine would have never happened. You will find his testimony before the FDA Advisory Committee on the safety of antidepressants in children chilling:

“I am Mark Allen Taylor and I am a victim of the SSRI antidepressant era. I took six to thirteen bullets in the heart area in the Columbine High School shooting when Eric Harris on Luvox opened fire that now infamous day. They almost had to amputate my leg and my arm. My heart missed by only one millimeter. I had three surgeries. Five years later I am still recuperating.

“I went through all this to realize that SSRI antidepressants are dangerous for those who take them and for all those who associate with those who take them. I hope that my testimony today shows you that you need to take action immediately before more innocent people like me, and you, do not get hurt or die horrible deaths as a result. As Americans we should have the right to feel safe and if you were doing your job we would be safe. Why are we worrying about terrorists in other countries when the pharmaceutical companies have proven to be our biggest terrorists by releasing these drugs on an unsuspecting public? How are we suppose to feel safe at school, at home, on the street, at church or anywhere else if we cannot trust the FDA to do what we are paying you to do? Where were you when I and all of my classmates got shot at Columbine?

“You say that antidepressants are effective. So why did they not help Eric Harris before he shot me? According to Eric they “helped” him to feel homicidal and suicidal after only six weeks on Zoloft. And then he said that dropping off Luvox cold turkey would help him “fuel the rage” he needed to shoot everyone. But he continued on Luvox and shot us all anyway.

“So, why did these so called antidepressants not make him better? I will tell you why. It is because they do not work.

“We should consider antidepressants to be accomplices to murder.”

Former FDA Reviewer Speaks Out About Suppression of Safety:

According to FDA whistleblower Ronald Kavanagh people would be shocked if they knew just how malleable safety data is. As examples, he points out that human studies are typically too short and contain too few subjects to get a clear picture of potential risks. In such a scenario, even a single case of a serious adverse event must be taken very seriously, and data from other longer term safety studies also need to be carefully analyzed. [This “even a single case of a serious adverse event must be taken very seriously” was our reasoning in putting the SSRIstories.com database in place. We did not want even one of these tragic cases to go unnoticed!]

The nation is at risk if FDA science is at risk…

“On one occasion, the company even told me they were going to call upper management to get a clear requirement for approval that they did not want to fulfill eliminated, which I then saw happen. On another occasion a company clearly stated in a meeting that they had “paid for an approval,” Kavanagh says.

Pediatric drugs also end up posing unnecessary risks due to the FDA’s failure to adequately review safety risks, and the many scientific loopholes employed by pharmaceutical companies. For example, the following flawed parameters are typically used in pediatric drug studies:

Dosages are based on approved adult dosages, without regard for metabolic differences between a developing child’s body and an adult
Exposure studies oftentimes use overweight children, and include too few children to adequately evaluate risks
No allowances are made for race, age, puberty, or actual weight
Dangers to pregnant women and their developing fetuses are also frequently ignored. The cost to us all is great whether we have taken these dangerous & deadly drugs or not, we all pay the price in higher insurance costs, higher taxes to support those now disabled and loss in productivity and contribution to society by those lost to the deadly effects of these unsafe drugs. All in all, the FDA appears to be engaged in a systematic hush-operation designed to give just about anything Big Pharma develops the green light. Essentially, dangerous drugs are given a rubber stamp of approval—the necessary go-ahead to make obscene profits while killing and injuring hundreds of thousands daily. It is, quite simply, inexcusable. The mainstream media has a lot to answer for as well, as their lack of reporting on these issues contributes to the problem by keeping a lid on reality.

Do I believe our media should be held accountable? Without a doubt! I have seen sections of newspapers discontinued for continuing to publish my information on antidepressant, major television shows canceled for doing a show on this subject, etc. This failure to warn on their part leaves blood on their hands as well. We NEED investigative reporters willing to cover the truth about something as critical as our health like Martha Rosenburg, the author of the original article containing this interview with an FDA whistleblower for the online news magazine Truth-Out. Our very lives are at stake in this. This is why Our International Coalition for Drug Awareness site is dedicated to the Washington Post reporter Morton Mintz who was awarded for his reporting keeping the deadly drug Thalidomide off the market in the United States. He is author of the incredible book giving us a very early warning of this approaching nightmare via the FDA, titled appropriately A Therapeutic Nightmare: A report on prescription drugs, the men who make them, and the agency that controls them (1965). In a telephone conversation in 1994 Morton Mintz told me to not to waste my time, energy, & resources publishing my book Prozac: Panacea or Pandora? – Our Serotonin Nightmare because no one would bother to read it & heed the warning just as they had not read his book & heeded the warning contained there. Then to my utter shock & amazement he told me that only 5000 copies of his book sold – an absolutely amazing book that I would recommend everyone have a copy of in their library!

This FDA whistleblower goes on to say that the FDA works to discredit whistleblowers & then even make it clear that speaking out may not only cost them their jobs, but also cost them their lives. Is that what has happened to Columbine survivor Mark Taylor? In face the evidence seems quite clear that this is the case. He may have survived 7 – 13 bullets at Columbine, but surviving the pharma mafia after speaking out against these drugs is another story! Pray for Mark! PLEASE!!!

Click here to continue reading the Dr. Mercola article: http://articles.mercola.com/sites/articles/archive/2012/08/13/drug-safety-whistleblower.aspx#_edn1

Read original article by Martha Rosenburg here: http://truth-out.org/news/item/10524-former-fda-reviewer-speaks-out-about-intimidation-retaliation-and-marginalizing-of-safety

Ann Blake-Tracy, Executive Director,
International Coalition for Drug Awareness
www.drugawareness.org & www.ssristories.drugawareness.org
Author: “Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Safe Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”

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ANTIDEPRESSANT: Mother of Columbine killer tells of horror 10 yrs after massacre

Michael Moore obtained a copy of Ann Blake-Tracy’s book at the premiere of his movie Bowling for Columbine. Now listen to his bold statement about what really did cause Columbine.


SEE FULL VIDEO Click here

INFO ON OTHER SCHOOL SHOOTINGS

Mark Taylors Site.
NOTE FROM Ann Blake-Tracy: Michael Moore, after reviewing all
the data on Columbine in making his movie, Bowling for Columbine, made his
message clear in the new movie The Drugging of Our Children about what he NOW
believes caused Columbine. Click on his picture to view his video
statement at www.drugawareness.org

In all of these articles out yesterday in the news covering the story by
Dylan’s mother there is STILL no mention of any medication use on Dylan’s part.
Yet we have a friend of Dylan’s who came forward claiming to have been helping
him withdraw from both Zoloft and Paxil.
But the coroner claims they found nothing in his system (I could go into
why that report is suspect but will save that for another time).
IF there really was nothing in his system, was Dylan in withdrawal from his
SSRIs at that point? We know that withdrawal can produce that same extreme out
of character violence since the REM Sleep Behavior Disorder (RBD) is more
prevalent in the withdrawal from these drugs than while on them. And yet of
those being diagnosed with RBD a staggering 86% were taking an antidepressant!
(To learn more about RBD read my FDA testimony on comedian Phil Hartman and is
wife’s Zoloft-induced murder/suicide – a classic case of RBD also found posted
at www.drugawareness.org.)
And if Dylan had been taking antidepressants were they prescribed to
Dylan? If not, where was he getting them? (Let us point out that anyone can
obtain these drugs easily. They have been sold in the streets since the early
90’s to be used recreationally and samples can be found ANYWHERE. Someone just
let me know that they found a bottle of Effexor in a shoe at a second
hand store!) Was a friend sharing their prescription? It happens regularly
from reports I get from kids. Were either of his parents taking one that he was
using for himself?
Years ago I was called in on a case of a 19 year old who was staying with a
married couple where the wife had been prescribed Zoloft and did not like how it
made her feel. She stopped taking it and placed in on top of the fridge. So when
the young man started feeling a little down he remembered the pills were for
depression and were suppose to help you feel better. So he took a couple, waited
a couple of hours and took more because he still was not feeling any better.
Then again took more a little later expecting to feel better right away. After

about five pills he recalls nothing about stabbing a man over 100 times with a
screwdriver.

Mother
of Columbine killer tells of horror 10 years after massacre

•Susan Klebold says she is haunted by school killings
•’I cannot look at a child without thinking about it’

Columbine High School student Dylan Klebold

Dylan
Klebold pictured in the 1999 Columbine High School yearbook. Photograph:
Reuters/© Ho New

The
mother of one of the two teenagers who murdered a dozen fellow students and a
teacher in the massacre at Columbine high school has broken a decade of

silence to say that she is unable to look at another child without thinking
about the horror and suffering her son caused.

Susan
Klebold, whose son Dylan and another youth, Eric Harris, hunted down pupils at
the Colorado school with shotguns, a semi-automatic pistol and a rifle before
killing themselves, has described her trauma over her son’s actions.

“For
the rest of my life, I will be haunted by the horror and anguish Dylan caused,”
she wrote in O, The Oprah Magazine. “I cannot look at a child in a grocery
store or on the street without thinking about how my son’s schoolmates spent the
last moments of their lives. Dylan changed everything I believed about myself,
about God, about family and about love.”

Neither
the Klebold nor Harris families has spoken about the massacre, in which 21
students were also wounded.

Klebold
recounts how the last word she heard from her son was a gruff goodbye as he
rushed out of the door early on the morning of the killings in April 1999.

“I
was getting dressed for work when I heard Dylan bound down the stairs and open
the front door … I poked my head out of the bedroom. ‘Dyl?’ All he said was
‘Bye.’ … His voice had sounded sharp. I figured he was mad because he’d had
to get up early to give someone a lift to class. I had no idea that I had just
heard his voice for the last time,” she said.

Dylan
Klebold was headed to make a final video with Harris to say goodbye and
apologise to their families before they drove to the school to plant bombs,
which failed to detonate, and to carry through their plan to kill their fellow
students.

After
the killings, the authorities said there were indications that the two youths
were disturbed and hints of the looming catastrophe. Harris’s blog included
instructions on how to make explosives and, later, angry denunciations of
society that attracted the attention of the police after Harris posted a death
threat against another student. Closer to the massacre, Harris listed his
stockpile of weapons and posted a hit list. Klebold was less overt but with
Harris made secret videos of their weapons and wrote in his diary of a desire to
plan an attack that would match the bombing in Oklahoma City by rightwing
militiamen that killed 168 people.

Klebold
writes that she had no idea that Dylan was contemplating killing himself or
anyone else. “From the writings Dylan left behind, criminal psychologists have
concluded that he was depressed and suicidal. I’d had no inkling of the battle
Dylan was waging in his mind,” she wrote.

“Dylan’s
participation in the massacre was impossible for me to accept until I began to
connect it to his own death. Once I saw his journals, it was clear to me that
Dylan entered the school with the intention of dying there. In order to
understand what he might have been thinking, I started to learn all I could
about suicide.”

Five
years after the killings, the FBI said they believe that Harris was a clinical
psychopath who masterminded the plan and Klebold depressive.

The
massacre continues to generate debate about the motives of the two youths and
whether anything could have been done to stop them. The magazine said that Susan
Klebold was not paid for the article and will not be making an appearance on
Oprah Winfrey’s television
show.


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Kauffman Study – (SSRI) Drugs: More Risks Than Benefits?

Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009

SSRI Bombshell by Joel M. Kauffman, Ph.D. Tuesday, March 31st, 2009

Selective Serotonin Reuptake Inhibitor (SSRI) Drugs: More Risks Than Benefits?

Joel M. Kauffman, Ph.D.

ABSTRACT

Anecdotal reports have suggested that selective serotonin reuptake inhibitors (SSRIs) may cause suicidal or violent behavior in some patients. Because of the publicity surrounding certain events, and the numerous lawsuits that have been filed, a review of benefits and risks is needed.

At most 30% of patients receive a benefit from SSRIs beyond the large placebo effect in certain mental conditions, especially depression, according to a recent meta-analysis of published trials. An equally recent meta-analysis of all SSRI trials submitted to the FDA showed a small benefit for the severely depressed patients only. Many early unpublished trials did not show any benefit. Adverse effects are common, occurring in up to 75% of subjects.

Severe adverse effects may be underreported.

Meta- analyses of controlled trials did not include any actual suicides or murders, but only suicidality, some finding, in 1991 and 2007, no evidence even of suicidality.

Other meta-analyses using many of the same trials found that suicidality doubled to 1 in 500 on SSRIs compared with placebo or non-SSRI antidepressants, but did not include any actual suicides or murders. The trial designs were devised by SSRI makers to prevent reports of suicides, by eliminating subjects with the slightest trace of suicidal tendencies. Retrospective studies by others showed actual suicides on SSRIs with a relative risk (RR) of 2–3 compared with non-SSRI antidepressants, with an increased incidence of 123/100,000. Lower doses than the smallest available ones were found to maintain benefits in a majority of patients while reducing risks.

table_03_zoloftbusted1

[PLEASE NOTE THAT THE SSRISTORIES DATABASE REFERRED TO BY DR. KAUFFMAN IN THIS STUDY IS NO LONGER POSTED AT THE URL LISTED ABOVE BUT HAS BEEN MOVED TO THE URL www.ssristories.NET ]

No causal connection between SSRIs and suicide and/or violence has been proved; neither has it been ruled out. Physicians need to be vigilant, and aware of legal precedents that may subject them to enhanced liability when prescribing these drugs. The Genesis of SSRIs Fluoxetine (Prozac in the U.S., see Table 1), introduced in 1988 to combat depression, was the fourth selective serotonin reuptake inhibitor (SSRI) on the U.S. market, after being seriously considered by Eli Lilly as an antihypertensive drug. Unlike the earlier “tricyclics” (amitripyline, clomipramine, dothiepin, imipramine, etc.) and other drug classes, SSRIs acted on the brain to raise levels of the neurotransmitter serotonin without raising the levels of norepinephrine. This was thought to be a benefit in treatment of depression, and later anxiety, panic, social phobia, obsessive- compulsive disorder (OCD) , and many other conditions. The SSRIs listed in Table 1 are among the most frequently prescribed in the U.S., and compete with the five non- SSRIs shown, and others.

ssri-drug-table1

Benefits of SSRIs

A prominent recent meta-analysis of Bridge et al. included 27 trials of SSRIs for three defined mental conditions: major depressive disorder (MDD), OCD, and non-OCD anxiety disorders. Benefits, compared with placebo, were found to be highly statistically significant. For MDD, data from 13 trials showed benefit in 61% vs. 50% on placebo, a gain of 11% absolute (NNT=10), <0.001 for all ages of participants. For OCD, data from six trials showed benefit in 52% vs. 32% on placebo, a gain of 20% absolute (NNT=5), <0.001 for all ages. For non-OCD anxiety, data from 6 trials showed benefit in 69% vs. 39% on placebo, a gain of 30% absolute (NNT=3), <0.001 for all ages. These results represent the maximum expectation of benefit from SSRIs since 22 of the 27 trials were financially supported by SSRI makers, and thus subject to the routinely positive bias of industry-sponsored clinical trials. Jay S. Cohen, M.D., author of the 2001 book , wrote that half his patients did well on fluoxetine, but he noted a high incidence (50%) with side-effects. Cohen also cited a pre-approval study showing that the standard 20 mg per day starting dose helped 65% of patients, while 5 mg helped 54%, so Cohen became one of the pioneers in using lower doses before Lilly made them available. The 1996 entry for paroxetine, at least, confirmed that the 17 most common side-effects were dose-dependent.

In four observational cohort studies of four common SSRIs reported by physicians as part of the prescription-event monitoring program in the UK, with more than 10,000 patients in each drug group, only 36% of the physicians reported fluvoxamine as effective, compared with 60% for fluoxetine, sertraline, and paroxetine. These possible benefit rates, which include the placebo effect, parallel the percentage of patients remaining on the drug for 2 months.

See: Over Dose: the Case Against the Drug Companies

An old trial of placebo for anxious and depressed subjects reduced distress in 43%. Three meta-analyses of the antidepressant literature that appeared in the 1990s independently concluded that two-thirds of the effectiveness attributed to SSRIs is actually placebo effect. In a series of nine controlled studies on hospitalized patients with depression, 57% of those given placebo showed improvement in 2–6 weeks. A 1998 meta-analysis of 47 trials on antidepressant medication including SSRIs indicated that 75% of the response to them was duplicated by placebo. This meta-analysis was criticized on several grounds. Therefore, Irving Kirsch, Ph.D., of the University of Connecticut, with other authors, obtained data submitted to the FDA on every placebo-controlled clinical trial on the six most widely used SSRIs, and published a meta-analysis on 47 trials, finding a small, clinically insignificant effect.

This work was updated in 2008:

Analyses of datasets including unpublished as well as published clinical trials reveal smaller effects that fall well below recommended criteria for clinical effectiveness. Specifically, a meta-analysis of clinical trial data submitted to the U.S. Food and Drug Administration (FDA) revealed a mean drug–placebo difference in improvement scores of 1.80 points on the Hamilton Rating Scale of Depression (HRSD), whereas the National Institute for Clinical Excellence (NICE) used a drug–placebo difference of three points as a criterion for clinical significance when establishing guidelines for the treatment of depression in the United Kingdom. Kirsch et al. concluded that the updated findings from 35 carefully vetted trials suggest that, compared with placebo, the four new- generation antidepressants ( fluoxetine, venlfaxine, nefazodone, and paroxetine) do not produce clinically significant improvements in depression in patients who initially have moderate or even severe depression.

They show statistically significant but clinically minor effects only in the most severely depressed patients. Moreover, the significance of the effect probably is based on a decreased responsiveness to placebo, rather than increased responsiveness to medication. Given these results, the researchers conclude that there is little reason to prescribe new- generation antidepressant medications to any but the most severely depressed patients unless alternative treatments have been ineffective. In addition, they write that the decreased placebo response in extremely depressed patients, combined with a response to antidepressants comparable to that of less severely depressed patients, is a potentially important insight that should be investigated further.

Even these unimpressive findings exaggerated the benefits of antidepressants. In three fluoxetine trials and in the three sertraline trials for which data were reported, the protocol allowed replacement of patients who, in the investigators’ judgment, were not improving after 2 weeks. The trials also included a 1–2 week washout period, during which patients were given a placebo prior to randomization. Those whose scores improved 20% or more were excluded from the study. In 25 trials, the use of other psychoactive medication was reported. In most trials, a chloral hydrate sedative was permitted in doses ranging from 500 mg to 2,000 mg per day. Other psychoactive medication was usually prohibited but still reported as having been taken in several trials.

Perhaps such considerations led David Healy, M.D., an SSRI expert, to his conclusion that “…these drugs do not convincingly work….” His evidence came from early unpublished clinical trials whose results were revealed to him at FDA hearings. For fluoxetine, Healy noted four trials with a positive result and four without. For sertraline, only one of five early studies showed benefit. Because of the huge placebo effect, 32–75%, most physicians unfamiliar with the studies revealing this effect are likely, in my opinion, to say that one-third to two-thirds of their patients are improved on SSRIs. This would also explain Dr. Jay S. Cohen’s findings on lower doses of fluoxetine.

SSRIs reportedly interact with 40 other drugs to cause “serotonin syndrome.”

This presents as twitching, tremors, rigidity, fever, confusion, or agitation. Serotonin/norepinephrine reuptake inhibitors (SNRIs) also may cause serotonin syndrome by interactions. Most tricyclic depressants do not have these interactions, with the exception of amitriptyline.

In a controlled trial of paroxetine vs. clomipramine sponsored by GlaxoSmithKline, 75% of the subjects had an adverse effect on paroxetine, 21% had a severe adverse effect, and 13% committed a suicidal act (1 in 8). The 1996 entry for paroxetine lists 17 side-effects with an incidence of ≥ 5% for approved doses.

They are: asthenia, sweating, constipation, decreased appetite, diarrhea (up to 15%), dry mouth (up to 21%), nausea (up to 36%), anxiety, dizziness, nervousness, paresthesia, somnolence (up to 22%), tremor (up to 15%), blurred vision, abnormal ejaculation, impotence, and other male genital disorders. Fully 31 additional side effects with an incidence at least 1% greater than placebo were listed, including uncontrollable yawning.

Murder, suicide, and suicidality were NOT [emphasis added] included.

Nor were they on comparable lists for fluvoxamine, or sertraline. For fluvoxamine, suicide were separately listed as “infrequent.”

For fluoxetine, suicidal ideation was listed as a voluntary report not proved to be drug related. For sertraline, suicidal ideation and attempt were listed separately as “infrequent.”

The entry for venlafaxine was: “…the possibility of a suicide attempt is inherent in depression.” Not found in the was weight gain, which Cohen lists as a serious side effect.

Typical dropout rates in recent trials are claimed to be 5% (see below), but these must be short trials, or trials with a run-in period. In a meta-analysis of 62 earlier trials with a total of 6,000 subjects, the mean total dropout rate and the proportion of dropouts due to side effects appear comparable to results in general practice: total dropout rates of between 30% and 70% have been reported by 6 weeks, of which some 30%–40% are attributed to side effects and the rest to failure of treatment. Early findings of severe adverse effects by SSRI makers came to light only after the class was established. Of 53 healthy volunteer studies on fluoxetine, the results of only 12 were openly reported.

From 35 healthy volunteer studies on paroxetine, pre-launch, the results of only 14 appeared. From 35 pre-launch healthy volunteer studies on sertraline, only seven appeared. Among the unpublished trials, there was one in which all volunteers dropped out because of agitation (akathisia). In published work on sertraline, data excluded material on behavioral toxicity, including at least one suicide of a Adverse Effects of healthy volunteer, and in a different trial, 2 of 20 volunteers became intensely suicidal. This last is consistent with the dropout rate of 5% for agitation alone in actual trials. It is also consistent with Lilly’s animal studies, in which previously friendly cats treated with fluoxetine started growling and hissing—an unheeded warning.

Just a year after fluoxetine was introduced, Bill Forsyth of Maui, Hawaii, had taken it for only 12 days when he committed one of the first murder/suicides attributed to any SSRI.

In the same year Joseph Wesbecker killed eight others and himself in a Louisville, Ky., printing plant where he worked, after 4 weeks on fluoxetine. Yet as early as 1986, clinical trials showed a rate of 12.5 suicides per 1,000 subjects on fluoxetine vs. 3.8 on older non-SSRIs vs. 2.5 on placebo! An internal 1985 Lilly document found even worse results and said that benefits were less than risks. Such documents were released into the public domain by Lilly as part of the settlement in the Wesbecker case. Fifteen more “anecdotes” of murder/suicide, three with sertraline, were listed by DeGrandpre.

Lilly’s denials of a link to murder/suicide on national television and elsewhere cited a sponsored meta-analysis in in 1991, which exonerated fluoxetine as a cause of suicidal acts or thoughts without even mentioning actual murder or suicide. This study included only 3,067 patients of the 26,000 in the clinical trials it utilized. None of the trials had a declared endpoint of suicidality.

Some of the trials had been rejected by the FDA. No mention was made that Lilly had had benzodiazepines co-prescribed to minimizethe agitation that had been recognized with fluoxetine alone. The 5% dropout rate for anxiety and agitation (akathisia) would have taken out the most likely candidates for suicide. Nevertheless, the 1991 study had its intended effect. For example, in 2006 a 900-page tome entitled , which was aimed at attorneys, cited this study, and failed lawsuits concerning SSRIs. The 2007 meta-analysis by Bridge et al. may be influenced by indirect conflicts of interest that are hard to prove based on the financial disclosures.

Their paper pooled excess risk above placebo for “suicidal ideation/suicide attempt” from 27 trials. The excess risk was said to be 0.7% and statistically significant across all indications, but significant within each indication. Of the 27 trials, only five were sponsored by the drug maker, and one of these, the 2004 Treatment for Adolescents with Depression (TADS) study of fluoxetine, had the highest rate of suicidality—7% above placebo. Most of the same trials were used in a meta-analysis by the FDA, which found a statistically significant excess risk of 2% (4% vs. 2% on placebo, 1 in 50 more). Bridge et al. used a random-effects calculation, while the FDA used a fixed-effects calculation.

In commenting on the negative findings, Bridge et al. write: “No study [in our meta-analysis] was designed to examine suicidal ideation/suicide attempt as a study outcome, and in fact most trials were conducted in patients who had been carefully screened to exclude youths at risk.” No actual murders or suicides associated with SSRI use were reported. Did the designs of the studies preclude detection or reporting?

The Bridge meta-analysis was not just a vindication of SSRIs, as communicated to the by Gilbert Ross, M.D., Medical Director of the American Council on Science & Health. Ross went further, commenting that the FDA “Black Box warning” (see below) was counterproductive because it was discouraging the use of antidepressants! Ross speculated that the lethal rampage of the Virginia Tech shooter might have resulted from premature cessation of medications.

SSRIs in general have long lifetimes in the body. Fluoxetine and its active metabolite in particular have a half-life of 16 days, according to the 1996 . In a reexamination of trials in which suicides or attempts during the inadequate washout period were not blamed on the drug, it was shown that the relative risk (RR) of suicidal acts ranged from 3 for sertraline to 10 for fluoxetine.

A concurrent meta-analysis of 24 trials by Kaizar et al. utilized Bayesian statistics, a valid choice, in my opinion, because data do not have to follow a Gaussian or normal curve to yield valid results, and this method can be used to revise probabilities to determine whether a specific effect was due to a specific cause. They found an association between SSRI use and suicidality with odds ratios of 2.3 (95% confidence interval [CI] 1.3-3.8), when the diagnosis was MDD, not OCD, anxiety, nor ADHD. Non-SSRI antidepressants were said to have no association with suicide. This supports the FDA’s findings and requirement, as of October, 2004, for a Black Box warning for all SSRIs, to monitor children and adolescents for suicidality. Kaizar et al. were concerned that there were no completed suicides among 4,487 subjects in the trials; that the trial times were too short at median length of 8 weeks; and that in 10 of the 12 MDD studies, Again, there was no citation of actual suicides associated with SSRIs and no citation of Healy’s work.

Healy reviewed epidemiologic studies that have been cited to exonerate SSRIs. One was analyzed by Healy to show a threefold increase in suicidality compared with other antidepressants.While “treatment-related activation” has been considered primarily with regard to suicidality, it can lead to harm to others as well as to self. Healy summarized data on “hostile episodes” provided by GlaxoSmithKline from placebo-controlled trials with paroxetine in subjects of all ages: 9,219 on paroxetine and 6,455 on placebo. The rubric of “hostility” was used in the trial to code for aggression and violence, including homicide, homicidal acts, and homicidal ideation, as well as aggressive events and “conduct disorders.” No homicides were reported from these trials.

Overall, during both therapy and withdrawal, the RR was 2.1 for hostile events. In children with OCD the RR was 17. Separately, in healthy volunteer studies, hostile events occurred in 3 of 271 subjects on paroxetine vs. none of 138 on placebo. In trials of sertraline on depressed children submitted by Pfizer, 8 of 189 subjects discontinued for aggression, agitation, or hyperkinesis (a coding term for akathisia), compared with 0 of 184 on placebo. In clinical practice, the term akathisia has been restricted to demonstrable motor restlessness, but if that is the only effect, it would have been called dyskinesia according to Healy, who cites four studies linking akathisia to both suicide and homicide.

Actual suicides were combined with suicide attempts in a 2005 meta-analysis of 702 trials of SSRIs vs. either placebo or an active non-SSRI control. Studies were rejected if the citation was a review, a result of duplicate publication, too short, crossover, or had no reporting of actual or attempted suicide. The studies meeting the criteria included 88,000 patients. For attempted suicide, the RR was 2.3 for SSRIs vs. placebo (95% CI, 1.14-4.55). The number needed to treat to harm (sometimes called the “reverse NNT”) was 1 in 684. There was no difference in actual suicide. Of the 702 trials, 104 failed to report adverse events below a certain pre-set limit of 3%, 5%, or 10% of patients. Only 493 trials reported dropout rates, with a mean of 29%, and the mean follow-up time was only 11 weeks. Thus, there was clearly gross underreporting of adverse effects. PDR children and adolescents with an elevated baseline risk of suicide were excluded.

Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009 9

More importantly, because actual suicides are involved, Healy cited a study by Donovan et al. that demonstrated a RR=3.4 ( <0.01) for SSRIs compared with all non-SSRI antidepressants involving 222 actual suicides, of which 41 were among patients who had an SSRI within a month of their suicide. Also the British Drug Safety Research Unit recorded more than 110 suicides in 50,000 patients taking an SSRI, an incidence of 219/100,000 compared with 96/100,000 for the non-SSRI mirtazepine (Remeron), an increase of 123/100,000, or 1 in 813 (Table 2). Thus the RR for actual suicide in patients taking SSRIs was 2.3 (or 2.8 for paroxetine). Even here, though, no murders were listed.

In another study cited by Healy, Jick et al. reported 143 actual suicides among 172,598 patients taking antidepressants. The relative risk of suicide in patients taking fluoxetine was 2.1, compared with those taking the tricyclic antidepressant dothiepin. The risk was not age-dependent. SSRI makers keep insisting that there will be more suicides if SSRIs are used as frequently as now. But the RR of 2–3 shown in studies is a number that the number of suicides that may have been prevented, so SSRI use is associated with more suicides, not fewer.

The International Coalition for Drug Awareness in cooperation with the Prozac Survivors Support Group has produced a website on which about 1,600 violent incidents associated with SSRI use are described ( www.ssristories.net ). The first column on the type of incident (murder, school shooting, etc.) is a hot link to a publicly available description of the incident, typically a local newspaper article. A selection of 10 entries (rows) is presented here as Table 3. About 360 suicides are tallied as well as about 400 murder incidents, many of which were multiple murders, each linked to 26 not net includesSSRIs Provide 1,600 Anecdotes of Violence SSRI use (Rosie Meysenburg, personal communication, 2008 .

As the number of “anecdotes” exceeds 1,600—hardly a small number—the association of SSRIs with murder/suicide, often combined, must be taken seriously. The SSRI website was searched to find combined murder/suicide incidents attributed to a specific SSRI. There were three for fluvoxamine, four for citalopram, 10 each for paroxetine and sertraline, and 31 for fluoxetine. Where the studies above substantiated suicide from SSRI use, the total on the SSRI website of 48 simultaneous murder/suicide incidents associated with SSRI use ties together SSRIs and murder. Since there were about two murders per suicide, we may infer that the murder rate on SSRIs could be about 250/100,000. Since no clinical trial involving multiple homicides is ever likely to be run, no firmer evidence is likely to be found. Healy noted that much of the evidence for suicide and murder came from the efforts of journalists and lawyers.
Note that the website carries a prominent warning that “withdrawal can often be more dangerous than continuing on a medication.” Nine violent events cited elsewhere—seven court cases of homicide (one attempted) and two assaults—were associated with specific SSRIs: three with paroxetine, three with sertraline, two with fluoxetine, and one with venlafaxine. Skeptics have cast doubt on whether the prescribed SSRIs were actually taken, especially since many medical records of juveniles were sealed. In the Columbine, Colo., shootings the toxicology report showed “therapeutic” levels of fluvoxamine in one of the shooters. The Red Lake, Minn., shooter had fluoxetine found, according to news items referenced on the website.

A 2004 editorial in by Simon Wessely, M.D., a spokes- man for Eli Lilly, and Robert Kerwin, Ph.D, cited only a single paper by Healy as a source of claims of suicidality that have found a receptive media audience. Tellingly, the only study described at length is by Jick et al. on the correlation of SSRI use and “attempted suicide,” in which the rates on dothiepin, amitriptyline, fluoxetine and paroxetine were not statistically different. Actual suicides in this study (seven on SSRIs) were not mentioned by Wessely and Kerwin, nor were the 143 suicides in Jick’s earlier paper. Jick et al. have been supported partially by GlaxoSmithKline and Pfizer. No study that reported actual suicides on SSRIs was described in detail, let alone refuted. Wessely and Kerwin wrote: “The problem is that depression is unequivocally and substantially associated with suicide and self-harm.” True, but this not the truth.

Table 2. Suicides Related to SSRIs or Mirtazapine

table_02_zoloftbusted1

The legal defense by Lilly, repeated by the media and others, is that any suicides are caused by the condition, depression, not by their drug—whether the violence is associated with short-term drug use, long-term drug use, increased doses, withdrawal, or rechallenge. There is no website, as far as I know, for violent acts committed by persons who never received SSRIs, or for total violent acts; hence the denominator for violent acts is not known. Also unknown is the fraction of potentially violent persons who are treated with SSRIs, or of persons treated with SSRIs who are potentially violent. The published studies on actual suicide, however, compare patients on SSRIs with similar patients on non- SSRI antidepressants or placebo. Children diagnosed with OCD, not depression, also became suicidal on SSRIs, as did healthy volunteers.

Actual two- to threefold increases in suicide rates have been demonstrated as well as they could be. How else could such effects be demonstrated? Who would submit, and what institutional review board or human subjects committee would approve a study explicitly designed to show whether assaultive, homicidal, or other violent behavior increases in subjects prescribed the study drug?

Denial by SSRI makers of culpability for these risks continues to this day. Whether physicians’ acting on the Black Box warnings of 2004 and 2007 for all SSRIs will diminish the incidence of murders and suicides is not yet known. Following the introduction of fluoxetine in 1988, only a year passed before an early user committed multiple murders and suicide; many other examples followed. More than 200 lawsuits have been begun by users of SSRIs and victims’ families charging wrongful death or failure to warn; these have had mixed outcomes. There is now legal precedent for SSRIs as a cause of murder, and the maker of the SSRI is potentially liable for damages, according to David Healy.

Eli Lilly responded with total denial to the lawsuits claiming a link between fluoxetine and violence. Several claims were settled out of court with secret details and no admission of guilt. The Australian David Hawkins was freed from a murder charge by a finding of temporary insanity caused by using sertraline. Tim Tobin of Wyoming won $6.4 million from SmithKline Beecham when a jury found that a murder/suicide committed by Donald Schell was attributable to use of paroxetine. There are four other homicide cases in which the SSRI was deemed to have contributed, resulting in a suspended sentence in one case and an insanity verdict in another.

One case of homicide, with a guilty verdict and a life sentence, followed a judicial ruling that akathisia was associated with SSRI use, but that a causal relationship with homicide could not be argued; thus the link of an SSRI with homicide was disallowed. This was in direct conflict with the findings of the four trials cited above. The SSRI website was searched to find murders related to a specific SSRI whose perpetrators were acquitted based on temporary SSRI-induced insanity. There were two cases with sertraline, four cases with paroxetine, and four cases with fluoxetine. So a precedent has been established for legal recognition that an SSRI can be a cause for murder, and that the drug maker can be found liable for damages. The notices of suicidality for the SSRIs found in the PDR or package inserts before 2004 did not really warn of actual suicide or murder.

200 SSRI-related Lawsuits

The Black Box warning of 2004 about possible suicide in children under 18 years of age did not cover adults or murder at any age, so potential liability for the SSRI makers still exists. In 2007 the warning was extended to persons under age 25 years. David Healy was quoted as saying that the warning was overdue, and that the risk was not likely to disappear above age 25. This was shown by the trials from GlaxoSmithKline on paroxetine cited above.

Antidepressants are extraordinarily difficult to assess for risks or benefits in trials. At most, 11%–30% of patients with depression or related conditions who take SSRIs actually benefited beyond the placebo effect on normal doses. Of the perceived benefit, 32%–67% can be attributed to the placebo effect. Adverse effects, mostly dose-dependent, will appear in up to 75% of patients on normal doses. Of these, studies suggest that suicidality will be observed in an additional 2%–13% (1 in 50 to 1 in 9) of patients on normal doses, beyond what is seen on placebo or many non-SSRI antidepressant drugs. This is sufficiently frequent that a typical prescribing physician should observe examples in routine practice.

The actual suicide rate could be about 123/100,000 (1 in 813) higher in patients on SSRIs than in those on tricyclics or placebo. Studies show that many more suicides are on normal doses of SSRIs beyond what is seen on placebo or many non-SSRI antidepressant drugs. Available data suggest that actual murders may be committed at about the rate of 250/100,000 (1 in 400) SSRI-treated patients beyond what is seen on placebo or many non-SSRI antidepressantdrugs, and that many more murders will be attempted on normal doses as well. While correlation does not prove causation, and results of court trials are not medical science, the data for suicide are solid, and the association of murder with suicide is very suggestive. Now that there is a stronger Black Box warning, physicians who ignore it may be liable for damages; the warning primarily protects the manufacturers of SSRIs. There is obviously great peril in drawing conclusions about causat i on from press report s or court decisions.

While manufacturers have a vested interest in exonerating their drugs, plaintiffs have an interest in blaming it, and defendants in exonerating themselves. We need careful, independent analysis of existing study data. In addition to randomized controlled trials, evidence from basic science ( neuropharmacology) and challenge/dechallenge/rechallenge investigations needs to be sought. Both the public and individual patients are imperiled by an incorrect answer to the pressing questions about these widely prescribed drugs. Future studies may show lower levels of murder and suicide with close supervision, and with better matching of this drug type to patient type.

Conclusionsattemptedsimultaneous
Joel M. Kauffman, Ph.D.

Acknowledgements:
Joel M. Kauffman, Ph.D., professor of chemistry emeritus at the
University of the Sciences, 600 S. 43rd St., Philadelphia, PA 19104-4495,
Contact: kauffman@bee.net.

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Frances E. H. Pane edited the manuscript. David Moncrief piqued my interest by providing a review copy of by Richard DeGrandpre.
The Cult of Pharmacology: How America Became the World’s Most Troubled Drug Culture

Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009 11
Potential conflicts of interest: The author has neither a financial interest in any drug mentioned, nor in any alternate treatments for treating any mental illness.

REFERENCES
DeGrandpre R.,Durham, N.C.: Duke University Press; 2006.

The Cult of Pharmacology: How America Became the World’s Most Troubled Drug Culture.
Bridge JA, Iyengar S, Salary CB, et al. Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment. 2007;297:1683-1696.

Jørgensen AW, Hilden J, Gøtzsche PC. Cochrane reviews compared
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the same drugs: systematic review. doi:10.1136/bmj.38973.
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Kirsch I, Deacon BJ, Huedo-Medina TB, et al. Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. 2008;5(2):e45. doi:10.1371/journal.pmed.0050045.

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Let Them Eat Prozac: The Unhealthy Relationship Between the Pharmaceutical Industry and Depression.
Worst Pills Best Pills News

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New York Times:Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009

USA Trade Name Generic Name:
SSRIs
Celexa
Luvox
Paxil
Prozac
Zoloft
non-SSRIs
Effexor
Remeron
Serzone
Wellbutrin
(UK)
citalopram
fluvoxamine
paroxetine
fluoxetine
sertraline
venlafaxine
mirtazapine
nefazodone
bupropion
dothiepin USA Trade Name Generic Name
SSRIs
Celexa
Luvox
Paxil
Prozac
Zoloft
non-SSRIs
Effexor
Remeron
Serzone
Wellbutrin
(UK)
citalopram
fluvoxamine
paroxetine
fluoxetine
sertraline
venlafaxine
mirtazapine
nefazodone
bupropion
dothiepin

Physicians Desk Reference (PDR)
Joel M. Kauffman, Ph.D.
Table 1. Commonly Prescribed SSRIs and Other Antidepressants Selective Serotonin Reuptake Inhibitor (SSRI) Drugs:
More Risks Than Benefits?

Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009 7 Physicians Desk Reference (PDR)
Joel M. Kauffman, Ph.D.
Table 1. Commonly Prescribed SSRIs and Other Antidepressants Selective Serotonin Reuptake Inhibitor (SSRI) Drugs:
More Risks Than Benefits?

Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009 7

JAMAwhole12,69210,98313,74112,73450,15013,554

10 dead, 7 wounded: dosage increased one week before rampage
15 year old shoots two teachers, killing one: then kills himself
Columbine High School: 15 dead, 24 wounded
Four dead, twenty injured after Prozac withdrawal
Teen shoots at two students: kills his father
Jury finds Paxil was cause of murder-suicide
Man cleared of charges due to Paxil withdrawal defense
Not guilty by reason of Prozac induced insanity: mother kills daughter
Nine dead, 12 wounded in workplace shooting
11 year old hangs himself: lawsuit

Journal of American Physicians and Surgeons Volume 14 Number 1 Spring 2009

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Michael Moore – Reveals the real cause of Columbine.


Michael Moore obtained a copy of Ann Blake-Tracy’s book, “Prozac: Panacea or Pandora? – Our Serotonin Nightmare” at the premier of “Bowling for Columbine” in Denver, CO. After learning more about these drugs, see his statement from the movie he recently appeared in with Ann Blake-Tracy, Mark Taylor, Neal Bush, and others in the Gary Null production “The Drugging of our Children” Full Video http://video.google.com/videoplay?doc… OTHER SCHOOL SHOOTINGS go to. http://www.ssristories.org/index.php AntidepressantsKill.com

Michael Moore obtained a copy of Ann Blake-Tracy’s book,

“Prozac: Panacea or Pandora? – Our Serotonin Nightamre”

at the premier of “bowling for Columbine” in Denver, CO.

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Columbine: The Mark and Donna Taylor Tragedy

On the 10th anniversary of the Columbine shooting, we had the opportunity to interview Mark Taylor and his mother, Donna. What we learned is shocking. In the last two years, Mark’s mental capacity has been totally eroded as the result of medications he received at two forced hospitalizations in 2007.

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Columbine victim and school shooter join forces

Sunday, 09 March 2008

Mark Taylor’s

testimony before the FDA 9/13/2004

I am Mark Allen Taylor and I am a victim of the SSRI antidepressant era.

I took six to thirteen bullets in the heart area in the Columbine High

School shooting when Eric Harris on Luvox opened fire that now infamous day.

They almost had to amputate my leg and my arm. My heart missed

by only one millimeter. I had three surgeries. Five years later I am still recuperating.

I went through all this to realize that SSRI antidepressants are

dangerous for those who take them and for all those who associate

with those who take them.

I hope that my testimony today shows you that you need to take

action immediately before more innocent people like me, and you,

do not get hurt or die horrible deaths as a result.

As Americans we should have the right to feel safe and if you were

doing your job we would be safe. Why are we worrying about terrorists

in other countries when the pharmaceutical companies have proven to

be our biggest terrorists by releasing these drugs on an unsuspecting public?

How are we suppose to feel safe at school, at home, on the street, at

church or anywhere else if we cannot trust the FDA to do what we are

paying you to do? Where were you when I and all of my classmates got shot at Columbine?

You say that antidepressants are effective.

So why did they not help Eric Harris before he shot me?

According to Eric they “helped” him to feel homicidal and suicidal after only

six weeks on Zoloft. And then he said that dropping off Luvox cold turkey

would help him “fuel the rage” he needed to shoot everyone.

But he continued on Luvox and shot us all anyway.

So, why did these so called antidepressants not make him better?

I will tell you why. It is because they do not work.

We should consider antidepressants to be accomplices to murder.

See Mark’s book “I
Asked, God Answered … a Columbine Miracle.”

See Mark's book

Tate
Publishing

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