Additional Tylenol Warnings: Now linked to SEVERE Asthma

NOTE FROM DR. ANN BLAKE TRACY (www.drugawareness.org):

YET ANOTHER TYLENOL WARNING! Long known toproduce fatal liver damage . . . how many warnings do we need to get the full picture on this deadly drug? There have been increasing warnings this past year which continues toexplain why Tylenol has NEVER been found in my medicine cabinet and never will be!!!

HIGHLIGHTS from the article below:

A pair of studies suggests that the common painkiller acetaminophen — better known as Tylenol in the U.S. — may be fueling a worldwide increase in asthma. ~Reuters Health

While no one knows if the drug causes asthma by itself, another report — published along with the first study — shows for the first time that many toddlers took acetaminophen before they developed asthma symptoms such as wheezing. [I am appauled by how often this deadly drug is given to young children!]

“We have confirmed that acetaminophen use comes first, SO A CAUSAL LINK IS INCREASINGLY LIKELY, [Emphasis added]” . . .

Acetaminophen tied tochildhood wheezing and allergies

4:15pm BST

By Frederik Joelving

NEW YORK (Reuters Health) – A pair of studies suggests that the common painkiller acetaminophen — better known asTylenol in the U.S. — may be fueling a worldwide increase inasthma.

According to one study out Thursday, acetaminophen could be responsible for as many as four in 10 cases of wheezing and severe asthma in teens.

While no one knows if the drug causes asthma by itself, another report — published along with the first study — shows for the first time that many toddlers took acetaminophen before they developed asthma symptoms such as wheezing.

“We have confirmed that acetaminophen use comes first, so a causal link is increasingly likely,” said Dr. Alemayehu Amberbir, of Addis Ababa University in Ethiopia and the University of Nottingham in the UK.

But large-scale clinical tests are necessary before anyone cleans out their medicine cabinet, stressed Amberbir, whose findings are published in the American Journal of Respiratory and Critical Care Medicine.

His team followed more than 1,000 Ethiopian babies over three years. When the toddlers turned one, the researchers asked the mothers if their babies had breathing problems, and how much acetaminophen they had used.

About eight percent of the kids began to wheeze between ages one and three. Those who had been given acetaminophen during their first year — before they had breathing trouble — had up to seven times the odds of developing wheezing.

That increase held even after adjusting for fever and coughs, which in principle could have triggered both the wheezing and the use of painkillers.

“What we have is further information and a stronger association between the use of acetaminophen and asthma,” said Dr. Dipak Kanabar, who has written guidelines on painkillers, but wasn’t involved in the new studies.

But Kanabar, a consultant pediatrician at Evelina Children’s Hospital in London, cautioned that parents’ recall isn’t always accurate, which could have influenced the findings.

“We have to be careful when we give advice to parents tostress that these studies do not mean that giving acetaminophen will necessarily result in their child developingasthma,” he said.

But if the link turns out to be real, it could have a major impact on public health, according to another report in the American Journal of Respiratory and Critical Care Medicine.

In that study, based on more than 320,000 teens from 50 countries, 11 percent of the children had breathing trouble — only slightly more than the percentage of American children who have asthma.

Those teens who took acetaminophen at least once a month — one third overall, and more than four in 10 Americans — doubled their odds of wheezing.

They were also more likely to have allergic nasal congestion and the skin condition eczema, Dr. Richard W. Beasley, of the Medical Research Institute of New Zealand, and colleagues report.

The researchers estimate that acetaminophen could potentially be responsible for up to four in 10 of all asthmasymptoms, including severe ones such as waking up gasping for air once a week or more.

McNeil Consumer Healthcare, the Johnson & Johnson subsidiary that sells Tylenol, said in a comment their product “has over 50 years of clinical history to support its safety and efficacy.”

“The well-documented safety profile for acetaminophen makes it the preferred pain reliever for asthma sufferers,” the company told Reuters Health in an e-mail. The company said there are no gold-standard clinical trials showing “a causal link between acetaminophen and asthma.”

However, Kanabar found in his review of the medical literature that ibuprofen — another painkiller, sometimes sold as Advil — seemed to trigger less wheezing than acetaminophen.

Ibuprofen, however, is not recommended in people withasthma, Kanabar said, and that most doctors favor Tylenol.

Aspirin, another common painkiller, is generally discouraged in children because it can cause short-term breathing problems and other rare side effects.

According to Kanabar, dropping painkillers entirely is probably a bad idea, and might cause a child to feel worse and drink less liquid, which could slow recovery.

So which painkiller should a parent choose if their child has a headache or a fever — Tylenol or ibuprofen?

At this point, said Kanabar, “you could go for either.”

SOURCE: link.reuters.com/sej74n American Journal of Respiratory and Critical Care Medicine, online August 13, 2010.

© Thomson Reuters 2010. TRACY (www.drugawareness.org):

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CELEXA: Woman Stabs Boyfriend: He Kills Her Before they Die: Florida

Last paragraph reads:  “Lori Adams had Tylenol and traces of the antidepressant Citalopram [Celexa] in her system, according to the toxicology report. She also had a blood alcohol level of .24. Marshall’s blood alcohol level is unclear, officials said. The toxicologist found a .15 level in his liver but could not get a blood alcohol level, Hunter said. He advised that Marshall’s level would have been much lower than Adams’ blood alcohol level.”

Paragraph four reads:  “Investigators have maintained that Lori Adams attacked Marshall first with a 7-inch kitchen knife. While she was able to cut him badly, Marshall managed to take the knife away from Adams and stab her to death, according to statements from investigators and reports from the Calhoun County Sheriff’s Office. Marshall then walked around his own home leaving a trail of blood until he slipped and fell next to Adams on the kitchen floor.”

http://www.newsherald.com/news/altha-77024-autopsy-confirms.html

Autopsy confirms double homicide

Lori Adams and Fred Marshall killed one another in rare case, investigators say

August 30, 2009 12:38:00 PM
By S. BRADY CALHOUN / News Herald Writer

ALTHA – The case of the Calhoun County couple who are believed to have killed one another in a knife fight might be at an end.

The autopsies for 46-year-old Lori Adams and 66-year-old Fred Marshall were released to the public Friday. The reports confirm what investigators have said since the couple’s bodies were discovered in Marshall’s Altha home on June 18, that Marshall and Adams killed one another in a rare double homicide.

“Pending some new information we have closed this case,” said Calhoun County Sheriff David Tatum. He added that it was “a very unique crime but a crime wherein both of the offenders and both victims died.”

Investigators have maintained that Adams attacked Marshall first with a 7-inch kitchen knife. While she was able to cut him badly, Marshall managed to take the knife away from Adams and stab her to death, according to statements from investigators and reports from the Calhoun County Sheriff’s Office. Marshall then walked around his own home leaving a trail of blood until he slipped and fell next to Adams on the kitchen floor.

One mystery that might never be solved is the exact date of the deaths. At a minimum Marshall and Adams had been dead for a couple of days by the time their bodies were discovered, said Dr. Michael Hunter, the medical examiner for Florida’s 14th Judicial Circuit. However, it is impossible to tell exactly how long their bodies laid next to one another in the kitchen of the Altha home, Hunter said.

The autopsy states that Marshall was stabbed seven times. He had wounds in the upper right chest, the upper right and upper left abdomen, two wounds on his right arm and two more in his left arm. Marshall had one incapacitating wound to his left arm, Hunter said, adding that it would have taken a long time for him to die from those injuries.

Hunter said his findings in Marshall’s death supports the theory that Adams attacked Marshall first and that Marshall took the knife away from her and stabbed her to death.

Adams’ autopsy states that she was stabbed 10 times and had wounds to the face, the upper abdomen, her back and her chest. The killing blow was to the left chest and penetrated Adams’ heart, Hunter wrote. After this blow, Adams would have died very quickly and would not have had time to stab Marshall, he said.

None of the injuries on either victim could be described as self inflicted, Hunter said, ruling out the idea that one party killed the other and then killed himself or herself.

Adams had Tylenol and traces of the antidepressant Citalopram in her system, according to the toxicology report. She also had a blood alcohol level of .24. Marshall’s blood alcohol level is unclear, officials said. The toxicologist found a .15 level in his liver but could not get a blood alcohol level, Hunter said. He advised that Marshall’s level would have been much lower than Adams’ blood alcohol level.

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