Wellbutrin and Effexor Made Me A Nervous Wreck

“My doctor was poisoning me.”


I have had numerous tragedies in my life. The worse being my 16 yr old son murdered 7 yrs ago, a brother died suddenly one month before. Both parents died , 9 mos apart in 85- 86. My nephew killed himself last year. I didn’t take antidepressants with the death of my son and divorce 9 mos later. I went to Christian counseling. It was hard. I lost 25 lbs. I made it through slowly and was happy, healthy again. These medicines were killing me. I kept thinking I was getting the flu. I know it was serotonin syndrome.

I became depressed after my nephew died. {He was born 9 mos. before my son, close growing up.}
I went to my primary care Dr. 3-02. He put me on one Effexor XR 150 mg daily. I was getting worse, not better.

I started going to a psychiatrist 10-02 after I had to quit my part-time job. I was sobbing in his office. He increased the EFFEXOR XR to 300 mg One Daily Dose. I slept all the time, thought the depression, didn’t care about anything, gained 13 lbs in all, didn’t want to leave the house, watch T.V., read etc.

He increased the Effexor XR 300mg and Wellbutrin 150 mg One Daily Dose. No better. No interest in sex.
I called two different times about the doses and administration, verification.

Another change to Effexor XR 150 mg and Wellbutrin 300mg One Daily Dose. Worse. A nervous wreck, couldn’t sit still, sighed constantly. 3-4 hrs sleep a night, losing concentration, unable to read, go to church, do much of anything.

He added sleeping pills first Trazadone, severe headache, changed to Ambien, headache, change to Sonata still headache.

Another change to Effexor XR 450 mg Daily Dose. I became so confused I couldn’t finish a sentence, forgetting what I was saying. I would start one thing in one room, forget, start something in another room. Drove on the wrong side of the road. Couldn’t find my counselor’s office {sis driving} after going to him 9 mos! My breast are swollen and tender.

I went to primary Dr. sobbing, worse, BP running 165/115 pulse 115-120. Having many migraines. Becoming suicidal, thinking “I am crazy”, so tired of all the medicines. He suggested I stop by Psych Drs office, he was already gone. I left a letter. His receptionist said I could go to Psych hosp. for eval . The Psych. Dr. responded by calling in Trileptal {100 mgs} No mention of appt.

Intake person said be glad I was just depressed, not “crazy”. He suggested a partial hospitalization program. Go 5 hrs a day, lunch and 2 breaks. Psych. Dr to monitor meds. I went 3 days. I was in a room with 15 people, group counseling. A murderer on my left, just out of prison, a girl who said ” I see dead people”, some people divorcing, death of family member. It was not for me.
However, the Psych Dr. I met shook his head when I told him about the meds. I was on. Three med students were with him. I mentioned my concern about “serotonin syndrome”. I also took 3 sumatripan shots a week for migraines. I had told other Dr about my concern. High SSRI’s and high SSRI antagonist doses. Even my neurologist said she had never heard of it ask the Psych DR! I had been having body aches, chills, shivering, severe nausea. My hands and feet were always ice cold. I was so thirsty I would drink 6 to 8 sodas a day also wake up in night and get water often. I even dreamed 3 times I was choking on gum etc. I have had a tremors, swollen, puffy face and hands, constipation. The new Dr and med students were concerned. The Dr. dropped meds down. Two wks later discontinued. However did put me on Celexa 20 mgs.

In two days already I could think clearly, finish my thoughts. Doing better with memory, finishing task. I am still aching, my lower back is sooo sore. I am experiencing “electrical shocks”. I am laughing again and eating better. This whole situation has been hell. Today day my BP was 117/80 soo much better, pulse 80!

I have been going to counseling every week since October. I fired original psychiatrist. I fired counselor for his ignorance. I fired neurologist I had for 8 yrs for her ignorance. I am beginning to get my life back. I have a patient husband. God has watched over me.
I trusted this Dr. He was poisoning me, with multiple contraindicated meds, potentially fatal.. I kept telling everyone something was very wrong. I pray I can stop someone else from experiencing this. I want to report this Dr.




This is Survivor Story number 13.
Total number of stories in current database is 48

Prozac nearly destroyed me.

“…my career, my entire family and almost all my friends abandoned me, and my health has been seriously compromised.”


In Feb. 2001 I had a severe psychotic reaction to Prozac that I barely survived. I became obsessive compulsive, extremely angry, paranoid, had racing and jumbled thoughts, etc… the result of this reaction was that I lost just about everything- all my money, almost all my possessions, my career, my entire family and almost all my friends abandoned me, and my health has been seriously compromised. I was dumped by my doctor ( he was my primary care physician- the HMO “Connecticare” could not provide me with a therapist (!) so I had to use this doctor- and he dumped me with a certified letter when I went to see him after the reaction because I was “uncooperative”!!!!

I can give you all the details you want, but what I want the most is for someone or some organization to look into this horror and do something about it to force those involved to face the truth and compensate me for my losses. I have NO money, and I am exhausted from 1 1/2 years of trying to deal with all the loss. I have had NO success getting ANYONE to help me so far. I cannot follow the advice I have most often heard which is to “let it go” because this was too painful and I almost did not survive.

I have never had this severe a problem in my life and I hope that you will be able help or at least refer me to someone who can.

I am 46 years old and I have been struggling and mostly succeeding with a 30 year battle with “mental illness”- I had not been on ANY medication for 7 years prior to taking the Prozac out of desperation- I had been doing well using alternative health methods. My story is one of extreme prejudice against me based on fear of “mental illness” and the refusal of almost all parties involved to look at the truth and at the evidence.

thank you for your attention



This is Survivor Story number 14.
Total number of stories in current database is 48

Zyban (Wellbutrin) “No Way”

“I think at this point the only thing that will save us is knowing about any medications before we take them.”


My husband’s horror story about Prozac and other SSRI anti depressants is posted in your web site– The Macula’s Story. We have been lucky because my husband is still alive. But we have been through a living hell, because our Primary Care Physician prescribed Prozac for my husband because he was a little down after our house burned. Who wouldn’t be?

Well last week I took my 17 year old son to our primary care physician for nasal congestion and a cough. While we were there I complained to our new Primary Care Physician, who we have been using for about 2 years now, that my son was smoking a pack of cigarettes daily. And that this was ridiculous at his age. The Doctor asked him why he was smoking and my son said, “school and work stress”. So The Doctor said to him, “I have something that will take the edge off the stress and the need to smoke”. Well I looked at the doctor and asked, “what that might be”. He said, “a new drug Zyban (Wellbutrin)”. I almost fell off the stool I was sitting on. This Doctor knew all about the adverse reaction that my husband had to Prozac and other SSRI anti-depressant drugs. We have explained it to him many times over the past 2 years.

I said, ” You forget I am the person who almost lost her husband to Prozac adverse reaction 2 years earlier, I couldn’t believe he wanted to prescribe this anti-depressant to my son. Knowing full well what had happened to my husband on anti-depressants”. He got somewhat defensive at this point and said, “this is not an SSRI anti-depressant like the others. This doesn’t work on the serotonin levels in the brain, this one works on the brain chemical dopamine”. I said, “after the hell we went through with my husband, my son will not take any medication that would alter any of his brain chemicals”.

Then I just told him, “no”. “There was no way my son was going on Zyban (Wellbutrin). I would not take the chance”. He then looked at my son, who will be 18 years old in 6 months. He laughingly told him, “come back to see me in 6 months”. I was very upset by this point. I felt like he was saying come back in 6 months so I can legally drug you without your mothers permission. Does he not think that my children went through hell also. Watching their father turn into a manic depressive, psychotic, suicidal wreck from a completely normal human being. Prozac and other anti-depressants took away their father for 1 12 years of their lives. Through my research and my finding Dr. Tracy, we helped him return to his normal self. But not without the pain and trauma it has caused all of us.

I have explained to this man over and over the hell and the trauma my husband and I and our children went through. Because some Doctor prescribed Prozac for a very stupid reason. Now I keep thinking, “I need to change Doctors”. But then I think “why”. They are all the same. They prescribe these drugs that they know nothing about. Have any of them stopped to read the adverse reactions or side effects these and any drugs can cause on the insert that come with the drugs. No, all they know is what the pharmaceutical salesperson tells them. And we know that the pharmaceutical sales person is not going to bad mouth their own medications. I think at this point the only thing that will save us is knowing about any medications before we take them. Know the adverse reactions and side effect they can cause. If you or someone you know has personality changes or things that seem different about them while on a medication, research it.

With my husband it took 1 1/2 years to realize what was going on, because we saw 5 or 6 different Doctors. I showed them the research I had done and what these drugs can do and I thought this was the cause of what he was going through. And they all said, “Prozac and these other SSRI drugs don’t do that”. Well my husband is living proof that they do. He didn’t get better until we took matters into our own hands and pulled him off all the medications they had him on. And about three weeks latter my husbands old personality started returning. But it took another 7 to 8 months for him to get to about 85% of his old self. He is still not 100% and we wonder if he ever will be. It is very frightening just going to the Doctors for my family and friends who saw what we went through anymore.

Patty Macula



Years 2000 and Prior

This is Survivor Story number 94.
Total number of stories in current database is 96