CELEXA: Murder-Suicide: Two Doctors Say Celexa Caused Tragedy: Ireland

NOTE FROM Ann Blake-Tracy (www.drugawareness.org):
Always keep in mind that 7% – 10% of the population lack the liver enzyme system necessary to metabolize the SSRI & SNRI antidepressants. Because of this 7% – 10% of the population will reach toxic levels quickly due to this inability to break the medications down. Although there is a simple test that would reveal who those 7% – 10% are BEFORE they are prescribed one of these drugs it is never given to patients. Anyway in 20 years of working with thousands, I have yet to find one who reports ever having one of these P450 2D6 liver enzyme tests run before a prescription is written for an antidepressant.
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Paragraphs four through seven read:  “The jury refused to bring in a verdict of suicide on account of the evidence given both by Professor of Psychiatry David Healy of the University of Cardiff and assistant state pathologist Dr Declan Gilsenan, who underlined the dangers of suicidal and homicidal acts arising from the use of SSRIs.”

“Professor Healy stated clearly that in a small but significant minority of patients using SSRIs can give rise to violent behavior including self-harm, suicide and violence to others, even up to killing them. He said that this was independent of any condition the patient might have, as the same symptomatology had been observed in healthy volunteers.”

“Dr Healy criticized the existing warnings for patients, as they give the impression that such feelings and behaviours are part of the patient’s complaint, and because they are not strong enough. ”The risk arises entirely from the treatment,” he said.

“The jury was obviously strongly influenced by his evidence and that of Dr Gilsenan, who testified to “toxic” levels of citalopram [Celexa] in Clancy’s blood, the active ingredient in the antidepressant Cipramil [Celexa] which he had been taking in the period leading up to the night of horrific violence in Bray in which he and Seb Creane died and Seb Creane’s brother, Dylan, and the latter’s girlfriend were lucky to escape with their lives.

http://psychiatricnews.wordpress.com/2010/04/16/irish-jury-implicates-ssri-antidepressants-in-deaths/

The Wellbeing Foundation

NEWSLETTER­ 15 April 2010

Foundation demands action from Minister after verdict of ‘not suicide’ by jury in Shane Clancy inquest

THE WELLBEING FOUNDATION has demanded that Mental Health Minister John Moloney act immediately to put in place proper protections for patients, their families, relatives and friends following the ‘not suicide’ verdict in the Shane Clancy SSRI-inspired double death case. The Irish Medicines Board is still funded by the drug companies, still remains one body despite the recommendations of an Oireachtas committee, and still issues weak and ineffective patient information leaflets with inadequate warnings of the dangers of the SSRI antidepressants which drove Shane Clancy to kill a college friend and then stab himself to death.

Please help our campaign to get effective protection for patients: write or email Mr Moloney supporting the three demands we set out in the press release.

Mr John Moloney, TD | Minister of State  Department of Health and Children, Hawkins House, Dublin 2 email

minister_moloney@health.gov.ie

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Verdict in Shane Clancy inquest is a call to action by Minister John Moloney

THE OPEN VERDICT returned by the jury at the inquest into the death of Shane Clancy is| a call to action on the part of Government, and particularly the Minister for Mental Health, John Moloney, to strengthen both the patient and doctor warnings relating to SSRI anti-depressants.

The jury refused to bring in a verdict of suicide on account of the evidence given both by Professor of Psychiatry David Healy of the University of Cardiff and assistant state pathologist Dr Declan Gilsenan, who underlined the dangers of suicidal and homicidal acts arising from the use of SSRIs.

Professor Healy stated clearly that in a small but significant minority of patients using SSRIs can give rise to violent behaviour including self-harm, suicide and violence to others, even up to killing them. He said that this was independent of any condition the patient might have, as the same symptomatology had been observed in healthy volunteers.

Dr Healy criticised the existing warnings for patients, as they give the impression that such feelings and behaviours are part of the patient’s complaint, and because they are not strong enough. ”The risk arises entirely from the treatment,” he said.

The jury was obviously strongly influenced by his evidence and that of Dr Gilsenan, who testified to “toxic” levels of citalopram in Clancy’s blood, the active ingredient in the antidepressant Cipramil which he had been taking in the period leading up to the night of horrific violence in Bray in which he and Seb Creane died and Seb Creane’s brother, Dylan, and the latter’s girlfriend were lucky to escape with their lives.

Both doctors also stressed that the high levels of the drug were not necessarily due to an overdose, but could have resulted from a build-up of citalopram resulting from it being slower to metabolise in Shane Clancy. Prof Healy recommended that the warnings in respect of this class of drugs be strengthened to emphasise that the drug can cause the problem, and that feelings such as suicidal ideation, agitation, restlessness, hostility and others are caused by the drug rather than by  the patient’s diagnosed condition. He stated that there should be compulsory monitoring of patients prescribed SSRIs at the starting period of their treatment, as the danger period is generally within the first two weeks and usually within the first days of taking the drug.

The Wellbeing Foundation supports Prof Healy’s recommendations. We wish to point out, yet again, that while in the USA and other countries the warning about possible suicidal and violent bahaviour is compulsorily displayed at the top of the patient information leaflet, in large, bold type and enclosed in a black box with a heavy bold rule all round, in Ireland the Irish medicines Board allows a mild warning of suicidal ideation to be included far down the text of the patient information leaflet and without any form of emphasis.

Dr Michael Corry, our founder, was hounded by the psychiatric establishment for stating last October that if Shane Clancy had not been taking SSRIs, this appalling tragedy, which has deeply affected two families and wide circles of friends and relations, would not have happened. A jury has now accepted that these drugs were implicated in these deaths and injuries which occurred during an outburst of insane violence.

We call on Minister John Moloney to move instantly on this matter in order to protect other young people and their families, and indeed anyone who may be prescribed SSRIs, from the possible consequences of taking these drugs. We call on Minister Moloney to do the following right away:

1. Instruct the Irish Medicines Board immediately to introduce a strong Black Box warning, similar to those in the USA and Canada, on the patient information leaflets for all SSRIs, SNRIs, and similar antidepressants; and also to strengthen the prescribing information for doctors to include a similar warning and to stress the need for close monitoring.

2. Make it obligatory for all prescribing doctors to carefully monitor all patients prescribed these same classes of drugs, including setting at least one return appointment on the date of prescription, so that the doctor can check the patient for any tell-tale signs and take corrective action.

3. We also ask the Minister to implement the relevant recommendations of the Oireachtas Committee on Health and Children in 2007, which he himself chaired at the time. The findings of this inquiry into the use of pharmaceuticals in Ireland included a finding that the structure and funding of the Irish Medicines Board were seriously flawed, and recommended that the IMB be broken up into two bodies, one to deal with licencing and one with pharmacovigilance or post-licencing safety monitoring. The committee also recommended that the present funding of the IMB, by the drug companies, should end and that this body should receive its funding from central government sources.

If further tragedies of this type are not to occur in future, with all the pain and suffering that they visit on parents, uncles, aunts, wives, husbands, or partners, other relations and friends of the victims, the Minister must act promptly to ensure that the public receives strong and adequate information on the real dangers posed by taking these drugs, and that anyone who is prescribed them is protected by a compulsory monitoring system.

Dr Aine Tubridy, Clinical Director of the Wellbeing Foundation, and Mr Basil Miller, the Foundation’s Director of Communications, are both available for further comment or interview.

To contact Dr Tubridy, call 01 2800084.

To contact Basil Miller, call 086 8182082

April 16, 2010 – Posted by Philip Barton | Blogroll | | No Comments Yet

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