FDA WARNS: DEPAKOTE (VALPROATE ACID) PRODUCES LOWER IQ IN OFFSPRING

pregnant woman

DEPAKOTE (VALPROATE) LOWERS IQ IN OFFSPRING

Drugs containing valproate (Depacon, Depakote, Depakote CP, Depakote ER, Depakene, Stavzor and their generics) are used to prevent migraine headaches, treat epileptic seizures and manic episodes associated with bipolar disorder. Drugs containing valproate already carry a boxed warning for birth defects.

According to the FDA the results of a recent study showed that children exposed to valproate products in the womb had lower IQ at the age of six than children who were exposed to other antiepileptics. And we should ask how much lower the IQ is in comparrison to children of mothers who take no antiepileptic drugs.

“Valproate medications should never be used in pregnant women for the prevention of migraine headaches because we have even more data now that shows the risks to the children outweigh any treatment benefits for this use,” FDA’s Director of the Division of Neurology Products, Russell Katz said.

www.reuters.com/article/2013/05/06/us-migrainedrug-fda-idUSBRE9450PS20130506

FDA warns on use of certain migraine drugs during pregnancy

Mon May 6, 2013 2:30pm EDT

(Reuters) – The U.S. Food and Drug Administration warned on the use of migraine drug valproate sodium in pregnant women as it could result in lower IQ scores in the baby.

The FDA said the results of a recent study showed that children exposed to valproate products in the womb had lower IQ at the age of six than children who were exposed to other antiepileptics.

Drugs containing valproate are used to prevent migraine headaches, treat epileptic seizures and manic episodes associated with bipolar disorder.

Abbott Laboratories’ Depacon, Depakote, Depakote CP, Depakote ER and Depakene, and Noven Therapeutics LLC’s Stavzor and their generics contain valproate. (r.reuters.com/nej87t)

Drugs containing valproate already carry a boxed warning for birth defects.

“Valproate medications should never be used in pregnant women for the prevention of migraine headaches because we have even more data now that shows the risks to the children outweigh any treatment benefits for this use,” FDA’s Director of the Division of Neurology Products, Russell Katz said.

This is the second time the FDA has warned on drugs containing valproate. In a June 2011 press release, the regulator had issued interim results of a study showing reduced cognitive functions in three-year-old children exposed to valproate.

(Reporting By Pallavi Ail in Bangalore; Editing by Roshni Menon)

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Posted in Recent Cases Blog, Scientific Studies.

Ann Blake Tracy, Executive Director,
International Coalition for Drug Awareness
(DrugAwareness.Org & SSRIstories.Net)
Author: ”Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”

She has specialized since 1990 in adverse reactions to serotonergic medications (such as Prozac, Sarafem, Zoloft, Paxil, Luvox, Celexa, Lexapro, Effexor, Serzone, Remeron, Anafranil, Fen-Phen, Redux and Meridia as well as the new atypical antipsychotics Zyprexa, Geodon, Seroquel and Abilify), as well as pain killers, and has testified before the FDA and congressional subcommittee members on antidepressants.

WITHDRAWAL WARNING: In sharing this information about adverse reactions to antidepressants I always recommend that you also give reference to my CD on safe withdrawal, Help! I Can’t Get Off My Antidepressant!, so that we do not have more people dropping off these drugs too quickly – a move which I have warned from the beginning can be even more dangerous than staying on the drugs!

WITHDRAWAL HELP: You can find the hour and a half long CD on safe and effective withdrawal helps here: store.drugawareness.org And if you need additional consultations with Ann Blake-Tracy, you can book one at www.drugawareness.org or sign up for one of the memberships for the International Coalition for Drug Awareness which includes free consultations as one of the benefits of that particular membership plan. You can even get a whole month of access to the withdrawal CD with tips on rebuilding after the meds, all six of my DVDs, hundreds of radio interviews, lectures, TV interviews I have done over the years PLUS my book on antidepressants with more information than you will find anywhere else for only $30 membership for a month (that is only $5 more than the book alone would cost) at www.drugawareness.org. (Definitely the best option to save outrageous postage charges for those out of the country!)

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