Chronic Or Permanent Stress Can Result In Mental Disorders


chronic stress

Antidepressant-induced Stress Can Produce

Mental Disorders and Brain Damage

A recent study in the Rubin science magazine has revealed that chronic or permanent stress’s effect on microglial cells — immune-competent cells responsible for repairing synaptic links, removing damaged synapses, and facilitating the growth of new brain neurons — can lead to the development of mental disorders, such as schizophrenia while another study out of the University of California demonstrates the same along with resulting in depression, suicide, ADHD, PTSD, Autism, brain damage and disrupts the balance and timing of communication in the brain.

When my book first went to press in 1994 I stressed this very issue pointing out Eli Lilly’s own studies demonstrating a doubling of cortisol, the marker for both stress and depression, with only one single dose of 30mg of Prozac administered! This fact went on the cover of my book as one of the most important things anyone should ever know about SSRI antidepressants. Then an entire chapter was included to discuss the damaging effects of cortisol, also referred to as the “death hormone.” The harmful effects of elevated cortisol have long been known to damage the brain as well as just about everything else in the body.

That should certainly help many of you suffering from the after effects of antidepressants to confirm what you are experiencing is the result of antidepressant use and to understand more about what you are dealing with as you work to repair that damage.

Additionally from this research we learn:

“In stress situations, the body readies itself for fight or flight, prepares itself for potential injuries, too,” lead researcher Dr. Astrid Friebe said in a statement. “What is certain is that microglial cells adapt to the new conditions, in a way. The more frequently they get triggered due to stress, the more they are inclined to remain in that mode. This is when microglial cells start to pose a danger to the brain.” ….

….A similar study conducted by researchers from the University of California, Berkeley also found that chronic stress can lead to changes in the brain that cause the development of a mental disorder. The research team focused on the reduction of neurons and generation of white matter that results from chronic stress. This increase of white matter, particularly in the hippocampus, disrupts the balance and timing of communication in the brain.”

Just out of curiosity one day (keep in mind this was before most of us realized we could just ask Google) I picked out a number for an endocrinologist in Salt Lake City, as if anyone should be aware of this important information an endocrinologist would be the one. I called to ask how long the human body could tolerate having the cortisol level doubled on a daily basis.

He gasped and said, “Oh you cannot do that to someone!”

I replied, “IF you could do that just how long could the human body tolerate that?”

He said, “A month, maybe two, three at the most. Why are you asking me this?”

I told him that is what one single 30mg dose of Prozac does.

His reply was, “Oh no! No! Prozac is a wonderful drug!”

He was completely unaware of this research done by the makers of the drug themselves because the study had been published in Italy, not the US, and therefore, the information was not required to be distributed to doctors in the United States. I gave him the reference to their study so that he could go look up for himself. This is one of the ways by which such mass ignorance of medications is generated….other than the fact that I have found far too many doctors do not bother to read research.

Read more in original article:

Ann Blake Tracy, Executive Director,

International Coalition for Drug Awareness &
Author: ”Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”

WITHDRAWAL HELP: You can find the hour and a half long CD on safe and effective withdrawal helps here: And if you need additional consultations with Ann Blake-Tracy, you can book one at or sign up for one of the memberships for the International Coalition for Drug Awareness which includes free consultations as one of the benefits of that particular membership plan.

WITHDRAWAL WARNING: In sharing this information about adverse reactions to antidepressants I always recommend that you also give reference to my CD on safe withdrawal, Help! I Can’t Get Off My Antidepressant!, so that we do not have more people dropping off these drugs too quickly – a move which I have warned from the beginning can be even more dangerous than staying on the drugs!

Posted in Education, Journal Articles, Recent Cases Blog.

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