WELLBUTRIN, Valium & Painkiller: Death: Overdose: New York

NOTE FROM Ann Blake-Tracy (www.drugawareness.org): I do wish doctors would learn that antidepressants and pain killers DO NOT MIX!!! They are deadly together and yet are so often prescribed together.

“Robert Guskind, the prolific yet troubled force behind the Gowanus Lounge Web site, died of “an accidental overdose” from a combination of prescription medication, the city’s medical examiner said.

Guskind’s March death was caused by “acute intoxication from the combined effects” of a painkiller and two antidepressants. He was 50 years old.

It took the medical examiner several months to complete the toxicology tests that found the painkiller hydrocodone, bupropion [Wellbutrin/Zyban] often used to help adults quit smoking), and diazepam (the generic name of Valium), circulating at lethal levels in Guskind’s system.”

http://www.brooklynpaper.com/stories/32/35/32_35_mm_guskind_death.html

September 2, 2009 / News / Carroll Gardens–Cobble Hill

Gowanus Lounge’s Guskind OD’d

By Mike McLaughlin
 Robert Guskind's death from an overdoseThe Brooklyn Paper

The Medical Examiner’s office now says Robert Guskind’s death from an overdose was accidental.

Robert Guskind, the prolific yet troubled force behind the Gowanus Lounge Web site, died of “an accidental overdose” from a combination of prescription medication, the city’s medical examiner said.

Guskind’s March death was caused by “acute intoxication from the combined effects” of a painkiller and two antidepressants. He was 50 years old.

It took the medical examiner several months to complete the toxicology tests that found the painkiller hydrocodone, bupropion (often used to help adults quit smoking), and diazepam (the generic name of Valium), circulating at lethal levels in Guskind’s system.

The three drugs are central nervous system depressants. They lead to drowsiness and, at high enough intake, can stop breathing.

It was not clear if Guskind had prescriptions for any of the drugs, but according to the assistant director of the emergency room at Long Island College Hospital, it would not be unusual for a doctor to administer them to a patient simultaneously.

“In the short course, I frequently prescribe [hydrocodone and Valium],” said Dr. Brian Blaufeux. Patients with back pain, for instance, could get the hydrocodone because it alleviates aching, and Valium, because it’s a muscle relaxer. “It’s certainly not uncommon for these to be prescribed together.”

Yet an inadvertent overdose is not a likely risk if the patients observe their recommended dosage, Blaufeux said.

“These two should not lead you to stop breathing,” he told The Brooklyn Paper.

But that appears to be what happened to the journalist, who was best known for his impassioned opposition to overdevelopment and obsession with discarded couches, which he diligently chronicled in photographs on GowanusLounge.com. In particular, he was fascinated with the transformation of Williamsburg, Coney Island and the area around the Gowanus Canal.

According to many, his death and, with it, the disruption of his popular Web site, have left a gaping hole in Brooklyn’s blogosphere.

One of his prophecies came to fruition in August when a warehouse near the Gowanus Canal partially collapsed.

“This thing has wall collapse written all over it,” the late great journalist said. He urged, “Do not go near this thing.”

©2009 The Brooklyn Paper

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CYMBALTA: Five Patients Commit Suicide During Clinical Trials: U.S.A.

NOTE FROM Ann Blake-Tracy (www.drugawareness.org):
So even though 19 year old bible college student, Tracy Johnson’s, suicide was the only one we heard about happening in the clinical trials with Cymbalta (taking place within Lilly’s own laboratory in a “healthy volunteer”), there were apparently FOUR MORE SUICIDES in the clinical trials?!!
Paragraphs five &  six read: “While people say many of Cymbalta’s side effects are manageable, some users experience effects that are extremely frightening and potentially dangerous. Some patients found the drug tends to trigger heart palpitations and increase anxiety levels and elevate the severity suicidal thoughts or impulses.”

“A 19-year-old college student who had shown no outward signs of depression killed herself at an Eli Lilly & Company laboratory in Indianapolis where she had been participating in a company drug trial for the experimental antidepressant. Four other patients who were given the drug during earlier trials also committed suicide.”

ADDITIONAL COMMENT BY Ann Blake-Tracy: HOW LONG ARE THEY GOING TO BEAT THIS RIDICULOUS HYPOTHESIS TO DEATH WHEN THERE IS ABSOLUTELY NO EVIDENCE, NOR HAS THERE EVER BEEN, THAT THE SSRI ANTIDEPRESSANTS DO THIS AND MOST ESPECIALLY THERE IS NO EVIDENCE THAT THEY “RESTORE BALANCE TO THE EMOTIONS”??????!!!!!!

I QUOTE ONCE AGAIN THE NEVER ENDING SEROTONIN LIE: “The drug works by preventing serotonin and noradrenaline from being reabsorbed back into the nerve cells in the brain. This helps prolong the mood-lightening effect of any released serotonin and noradrenaline, restoring balance to the emotions of the patient.”

http://www.emaxhealth.com/1357/25/33042/cymbalta-side-effects.html

Submitted by Tyler Woods Ph.D. on Aug 22nd, 2009
Posted under:

Cymbalta, generic name Duloxetine Hydrochloride, has certain side effects consumers should be aware of.

Cymbalta manufactured by Eli Lilly is a serotonin norepinephrine reuptake inhibitor (SNRI) antidepressant used to treat major depression. It is prescribed to treat pain associated with diabetic peripheral neuropathy, which is a painful nerve disorder associated with diabetes that affects the hands, legs, and feet. Cymbalta has only recently been approved for use to treat fibromyalgia if people can tolerate Cymbalta’s side effects.

The drug works by preventing serotonin and noradrenaline from being reabsorbed back into the nerve cells in the brain. This helps prolong the mood-lightening effect of any released serotonin and noradrenaline, restoring balance to the emotions of the patient. Cymbalta may also be used in the treatment of generalized anxiety disorder.

Among the more common Cymbalta side effects that users complain about is being fatigued even after a good night’s sleep. Blurred vision, dry mouth, nausea, vomiting, and issues with both constipation and diarrhea, agitation, irritability, increased, hostility, high blood pressure, decreased libido, hot flashes, fatigue, rash, and increased sweating have also been reported.

While people say many of Cymbalta’s side effects are manageable, some users experience effects that are extremely frightening and potentially dangerous. Some patients found the drug tends to trigger heart palpitations and increase anxiety levels and elevate the severity suicidal thoughts or impulses.

A 19-year-old college student who had shown no outward signs of depression killed herself at an Eli Lilly & Company laboratory in Indianapolis where she had been participating in a company drug trial for the experimental antidepressant. Four other patients who were given the drug during earlier trials also committed suicide.

Anyone taking Cymbalta should understand that they can be at risk while driving, handling machines, or performing other hazardous activities such as working on tall ladders as it can cause dizziness or drowsiness.

Many people report that there were no Cymbalta side effects except for a lowered sexual drive and feel the drug gave them back their life. Like other antidepressants, Cymbalta should not be stopped suddenly if you have been on it for some time. Your brain receptors will adjust to it, and suddenly stopping can cause crying jags, agitation, dizziness, nausea, or headache. You should always talk with your doctor or healthcare provider to work out a plan to slowly decrease your medication to avoid withdrawal symptoms.

People are encouraged to report negative side effects of prescription drugs to the FDA. Visit

www.fda.gov/medwatch, or call 1-800-FDA-1088.

References
New York Times
Drugs.com
Source:
Tyler Woods Ph.D.

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