ANTIDEPRESSANTS: Star D Study – Only 3% Remission, Not 67%

Last paragraph reads:  “”Although the study‘s reports make no
mention of this outcome, their data show that after a year of continuation
treatment following remission, of the 4,041 patients who entered the program
only 108 (3%) had a sustained remission — all the other patients either dropped
out or relapsed. Yet STAR*D‘s authors and the NIMH have publicized the study as
showing a 67% success rate for

antidepressants.”

http://www.psychologytoday.com/blog/mad-in-america/201005/update-the-stard-report
May 19, 2010, Psychiatry

Update on the STAR*D Report
The
documented recovery rate in the STAR*D trial–worse than thought?
Published
on May 19, 2010

Two months ago, I wrote a post about a New Yorker
article that reported that 67% of the depressed patients in the STAR*D trial
“recovered.” As I noted in that post, the 67% figure was a highly exaggerated
number. Only 51% of the 3,671 patients who entered the trial ever remitted, even
for a short period. Furthermore, only about 20% of the patients remitted and
then reported to STAR*D investigators, at some point during a 12-month follow-up
period, that they were still doing well.

But this left an obvious
question, one that I hadn’t been able to find an answer to in the published

STAR*D reports. How many of the 3,671 people who entered the trial remitted and
then stayed well and in the trial throughout the entire 12-month follow-up? That
number would provide a documented long-term recovery rate for patients in the
trial.

A few days ago, Allan Leventhal sent me a 2009 article he
coauthored with David Antonuccio, and in it, they successfully identified this
number (finding it in a confusing graphic I hadn’t been able to decipher.) In
their computations, they relied on STAR*D reports that told of 4,041 initial
participants (3,671 was the number of “enrolled” patients counted in the
analysis of drug-remission rates), and then they came to this bottom-line
conclusion about the documented long-term recovery rate:

“Although the

study‘s reports make no mention of this outcome, their data show that after a
year of continuation treatment following remission, of the 4,041 patients who
entered the program only 108 (3%) had a sustained remission — all the other
patients either dropped out or relapsed. Yet STAR*D‘s authors and the NIMH have
publicized the study as showing a 67% success rate for antidepressants.”

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Suicide After Only a Month on Celexa

“…depression worsened on Celexa.”

 

My son, age 46, had battled depression, anxiety & panic attacks for many years. He was using Wellbutrin & Xanax. In early June, 2001, his psychiatrist prescribed Celexa. On June 18th, he saw his shrink again to report that his depression was worsening. On June 28, 2001, he shot himself in the head.

The monograph on Celexa under “PRECAUTIONS” states that “the possibility of a suicide attempt is inherent in depression and may persist until significant remission occurs. Close supervision of high risk patients should accompany initial drug therapy”.

A sorrowing Mom in FL.

 

8/6/2001

This is Survivor Story number 18.
Total number of stories in current database is 34

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