4/16/2000 – More from Boston Globe on Drug Safety Issues

This story ran on page A10 of the Boston Globe on 5/15/2000. © Copyright 2000 Globe Newspaper Company. A BOSTON GLOBE EDITORIAL Better drug reporting deal with a wide range of conditions, from depression to osteoporosis, doctors are reaching increasingly for their prescription pads. Patients who consume these drugs have faith that any side effects…

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The Aftermath of Antidepressants

Note: Keep in mind that these drugs are all serotonergic agents and clones or “copy cat” drugs of Prozac – the first SSRI antidepressant introduced to the market in America. Basically what applies to one, applies to the others. For instance we have more data out on Prozac because it has been around longer, but as the mode of action is the same for all of these meds the effects will be the same for the other drugs on this list as it is for Prozac. If we are discussing one drug, similar effects would be expected from any other company’s version of the drug. In fact it would be more honest to give them the titles of Prozac #1, Prozac #2,Prozac #3, etc. rather than the brand names they have been given, from the second clone, Zoloft, to the latest Prozac clone, Celexa.

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6/1/1999 • Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid.

6/1/1999 • Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid. Martensson B, Nyberg S, Toresson G, Brodin E, Bertilsson L Department of Psychiatry, Karolinska Hospital, Stockholm, Sweden. Acta Psychiatr Scand 1989 Jun; 79(6); 586-96 During treatment the 5-HIAA concentration decreased by 46%. Fluoxetine treatment…

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