My 18-Year Old’s Bizarre Behavior on Prozac

“At no time …did any one mention Prozac’s side effects.”

My 18 year old son has been on Prozac for the last year and a half.
Initially, I brought him to a counselor for some mild anxiety he was experiencing (shyness in social situations, etc.) The counselor (a licensed MSW) prescribed Prozac, saying that it would greatly reduce Jeff’s anxiety. Indeed, after two weeks Jeff reported feeling better, being more relaxed in school and in social situations. Over the next 6 months or so, however, I began to notice some disturbing symptoms (excessive sleepiness at times and at other times extreme agitation along with an inability to concentrate on schoolwork).I told his family doctor, who suggested cutting his dose of Prozac, from 20 mg. to 10 mg. Shortly after this time, Jeff began to develop a severe drinking problem. He frequently came home so intoxicated that he could not stand and remembered nothing the next morning. His grades in school also started plummeting: during his senior year in high school, his grades went from B+ to failing. He was extremely agitated, anxious, unable to sit still or focus. At this point his counselors recommended that his Prozac be upped from 10 to 20 mg.

Things went from bad to worse-his drinking increased, he barely graduated from high school (he was on home study because he was exhibiting bizarre, sometimes threatening behavior in school, and was suspended).At no time during this period did any one mention Prozac’s side effects or the possibility that Jeff was having a serious reaction to this drug.

Finally, towards the end of summer ’99, when he picked up his prescription from the pharmacy, he read the label and noticed some of the possible side effects, pointing out to my husband and myself that these were the same things he’d been experiencing. We made a family decision to stop the Prozac, not realizing that the fun was just beginning. About a week after stopping the Prozac, Jeff began to have panic attacks (something he’d never experienced before).Along with the shaking, irregular heartbeat and anxiety, he experienced strange sensations in his head and a buzzing sound in his ears. We went to see his doctor, who didn’t make the connection-he sent him to a psychologist to treat the panic attacks, not suspecting that the problem might be Prozac withdrawal (nor did I). For the past 2 months, his symptoms have grown steadily worse: he’s been in the emergency room for severe headaches, has seen a neurologist, had many expensive tests, and been diagnosed with Migraine.

No one made the connection between his symptoms and the fact that he had stopped the Prozac abruptly (all doctors knew of his decision). It wasn’t until I saw Dr. Tracy on the Leeza show recently that I started to suspect that this might be the problem. Since then I’ve been researching Prozac on the internet and am amazed at the information I’m finding! I’ve spoken to Jeff’s doctor who was as surprised as I about these complications (I printed and mailed him lots of info.)I will order your book, as I want to know what I can do to help my son at this point apologize at the length of this e-mail, but I had to tell this story to someone.
Thank you.

Followup Letter to Dr. Tracy:
Dear Dr. Tracy,
Thank you for your kind response to my e-mail. It’s obvious that this is an issue very close to your heart. It’ s easy for me to see how frustrating this battle can be: the more information that I find on this topic, the more appalled I become that the medical and psychiatric professions are allowing this to happen to unsuspecting and trusting patients. Amazingly, Jeff seems to be doing much better. Just within the past week, his headaches have all but disappeared, and his anxiety level is greatly diminished. It’s been about 2 1/2 months since he stopped taking the Prozac- from what I’ve read however there can be delayed withdrawal reactions, so I’m not sure we’re out of the woods yet. I’ve been very busy printing information that I find on the internet and sending Jeff’s doctor and counselors letters and packets of information. My hope is that they will at least begin to question these drugs and do some research on their own. I’d like to show you an excerpt from the letter I wrote to the psychologist Jeff was referred to for the panic attacks he experienced shortly after discontinuing the Prozac. I am particularly annoyed with this doctor because he told me that Jeff’ panic attacks were the manifestations of OCD and that he needed to be on medication. From letter to Dr. Robbins: Coincidentally, now that Jeff’s withdrawal symptoms seem to have abated, he is much more like the son I once knew. He’s more relaxed, he’s stopped drinking, his sense of humor is back, and he’s actually able to focus on schoolwork ( he got an A on a recent College Comp. paper.)What does this say about Prozac? Basically, I feel that this drug took my son away from me for two years! I have also written a letter to the Rochester editorial page; a Speaking Outessay. I’ll let you know if they print it. If there’s any way I can help you with this cause, please let me know .I feel very strongly about it: this drug took my 16 year old son, who had been identified as gifted, was well-liked by his peers, and had a great sense of humor, and reduced him to a barely functioning shell of a person. I am thankful to you and God for rescuing us from this terrible shadow that hung over our lives.

Yes, I would like my e-mail (the original and this reply) posted on your website. You may include my first name and e-mail address. I would also like to remind people who’ve had negative experiences with Prozac or another anti-depressant to send a med-watch complaint to the FDA. The number for your local FDA is in the Federal organization section of the phone book. There is also a link from this ICFDA web site.] The more complaints they get the more likely it is they’ll investigate (I hope, unless they’re in this with the drug companies- but that’s a whole different topic)

Patti582@aol.com

2/27/2000

This is Survivor Story number 27.

Total number of stories in current database is 96

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How Prozac Shattered My Life.

“I believe that any innocence that I held before these events occurred has now been dashed but I am never without hope.”

 

I have “hummed and hawed” for the last three days about writing to this address – people who have experienced a negative reaction to Prozac are perhaps understandably reticent about publicizing their experience, in the belief that what they will say will be treated with some skepticism, if not disbelief. These preparatory remarks are perhaps my response to the professional incredulity the medical fraternity, rightly or wrongly, give to their patients when anecdotal evidence is offered that contradicts their expected prognosis.

I had great faith in my doctor, in the treatment of what was a reactive depression brought about by work-related stress. I still have that faith, although it is not blind as it was before thanks to your pages on the WWW.

I am prompted to write because of “Patty’s” description of her husband’s course of treatment. The similarities to my own situation, after having spent some two years on Prozac, are remarkably similar. The devastation that has been wrought by my illness is now past, and I am now a sadder but wiser person. I have little to gain by writing other than to add to the growing list of patients who have had an adverse reaction to Prozac. But perhaps by writing others may persist and recognize that Prozac and the serotonergic syndrome are not figments of the patient’s imagination, but worthy of protracted study and explanation. I seek not to apportion blame, but to understand and be understood.

Without going into gross details, I had been taking Prozac with little positive effect for some 8 months from June 1994 until mid-way through 1995 before recognizing the possibility that there was something not quite right with my response to the medication. My agitation had gradually increased from the start of the prescription. It was a slow but steady rise in my tolerance of others, a deepening insomnia and above all the nightmares; nightmares that took me back to events that had happened when I had been a police officer nearly 15 years previously. I would jerk awake or my sleep would be interrupted by hyperreflexia. For some three months my average sleep was no more than one hour per night. The thought of sleep itself began to horrify me. The most obvious signs now as I look back were a feeling of electricity pumping through my body, the feeling that my limbs were charged and tingling.

I had been experiencing a tightness in the chest and was eventually taken into hospital, where blood tests showed that I had had a heart attack. Further tests eliminated this and it was put down to stress.

Sadly, I did not tell my doctor of these events, as I felt these were signs of my continuing decline into a deeper depression. My public life was no different, but my private life deteriorated rapidly as I struggled with the lack of sleep. I was prone to fits of crying and started to inexplicably want to harm myself. I banged my head against walls until I bled, tore shirts from my body, pleaded for help from my partner. My physical rage was barely controllable, but luckily for my partner, directed solely at myself. Verbal abuse at this stage became my only outlet. Anxiety became a single factor in all that I did. Whatever I thought I was about to accomplish in terms of work, I saw was imperfect. I became fearful of the most innocuous of social situations and work-related situations, although my work performance was unaffected. I hid this from all except my partner who tolerated everything believing that I would “come right”. My fear was simple – I was losing grip on reality and madness was not far away. A reluctance to communicate these events was eventually my undoing. The dosage of Prozac was increased as I related only those events that affected me physiologically.

Following some further work-related disagreements, I did not sleep for some seven or eight days. My internal rage became intolerable. I resigned from work and promptly collapsed mentally and was placed in a private hospital for sleep. Lithium was prescribed and the dosage of Prozac increased. I spent two days crying and did not sleep one bit, the nightmares returning almost the moment that I dropped of to sleep. My body sang with pain and I remember crawling into the corner of my private room crying. I saw myself spending Xmas on the streets, begging for food. I begged to be released from hospital and was. All I wanted was to go home, but my home life was now shattered irretrievably.

I felt cut off, entirely isolated from those that I loved and cared about and so three months later I left after another argument, more alone than alone. There was of course no change in my medication. Somehow I managed to obtain another job and hid my fear in work, but my private life and mental well-being was slipping beyond my grasp. Suicide was not an option that I had considered in all seriousness, but now it became a logical way out of the intense flailing that I gave to myself. I weighed up all the options and decided to take my life. It was the only way out; the only rational act that I could follow.

My fear of being found out – that I was mad – was such that I still did not report what was actually happening in my mind. Having decided on a course of action – my car with a pipe attached to the exhaust – I set about convincing myself that I could do it. Somewhere inside I could not muster the courage and broke down in tears. A call to a crisis center brought temporary relief. I still continued working, and those hours when I could deal sanely with people, were ones that held hope.

I took up sport again and played competitively, until I damaged my ribs and was prescribed a anti-inflammatory drug.

My sleep prior to this period was still plagued by nightmares and this incredible jerking of my limbs. Again, I put this down to the extreme personal stress that I was under. What other explanation could there have been? And the dosage of Prozac was evidence that I was not responding well enough.

Two days after I took the anti-inflammatories, I prepared for sleep. I felt a growing agitation and the electricity beginning to spark through my limbs. I began to tremble uncontrollably and I wanted to run and run this pain out of my system. I got to the stage where I considered jumping out of the window of the third floor flat in which I was staying. I have no recollection of anything from that night other than the fear that I felt. In desperation an ambulance was called. I struggled to keep my mind in place as the tremors increased. I kept saying, “I’m going to jump! No, I won’t. I won’t!” My heart raced, my mind raced and I saw everything that I wanted in life slipping away.

Taken to the emergency section of a major hospital, I was placed in a priority queue, strapped onto a gurney. The humiliation still rankles. I was not seen for another three hours, by which time the “panic attack” as it was described, had subsided. I told the doctor of my medication, and my suspicions that it was the combination of Prozac with the anti-inflammatories that might have been the problem. The response was luke warm, as I explained my medical history. I was told that a report would be forwarded to my doctor and I was released in the early hours of the morning, on my own recognizance”.

It was only at this stage that I began to question the use of Prozac. But who was I to correct the knowledge of the medical profession? My dose was increased. Again, because of certain delays in seeing my doctor, I gained confidence again, and submitted myself to the further dosage.

It is now some 18 months since these events, and following acupuncture treatment from my GP for the continuing “pain”, I began to seek another explanation for my continuing moroseness. Gradually (and wrongly!) I tried cold-turkey and eventually a change in psychiatrist last December, 1997. This brought a change in medication and with it a gradual return to normality.

At no stage (and this is current) has it ever been discussed that Prozac may have been a contributing cause to my continuing illness. Indeed, that it may have masked what appears to be a particularly traumatic set of events, has never been canvassed.

I now live with hope, an intuitive hope that I believe that Prozac may have been in some way a contributing cause to what on the face of it was a work-related stress problem, that had become far worse as a result. Of course, I have no empirical reason to believe that this unconfirming data is of any consequence to the scientific community.

Since being off Prozac there have been no bouts of anxiety (other than the more healthy kind), my sleeping has gradually increased to five hours per night, my nightmares have all but disappeared and above all there is a relative sense of a return to who I was.

Throughout this period of time, I have continued to work, hiding my private fears through enforced isolation from those that I care deeply about. There is a cost of course – an immense emotional cost. I am only troubled now by a search for truth, a truth for which, I may of course, never find an answer. Mental illness carried with it a stigma; a stigma about whether what we have become has any rational cause. Any self-knowledge that can be gained through the horrors of what I have gone through, from the absolute despair of confusion and loss of those that we care about the most, is tinged with intellectual and emotional frustration. It requires a faith and trust in those around us. I believe that any innocence that I held before these events occurred has now been dashed but I am never without hope.

I do not know whether these words will be of use, or my experience in anyway enlightening. I know that your work is important to a future generation, a future generation that may be educated to question more extensively than I myself have done.

Thank you for your time. May your work continue and prosper.

Two Years After Prozac: An Update

“It has been some time since this was written and you may be interested in a follow-up that reveals perhaps the more insidious side of the “idiosyncratic drug reactions” that are so often innocently missed.”

I am the “AG” who appears on the “Survivor’s Links” under the title “How Prozac Shattered My Life” on your web site.

It has been some time since this was written and you may be interested in a follow-up that reveals perhaps the more insidious side of the “idiosyncratic drug reactions” that are so often innocently missed. I have now been “off” Prozac for almost two years and, although almost back to normal, I was recently diagnosed with Left Ventricle Hypertrophy (an enlarged heart) and Hypertension in April 1999. I am currently on medication to reduce my blood pressure (which has been very successful) and lucky enough to be treated by a heart specialist who is specializing in serotonin and its relationship to high blood pressure.

I have no scientific reason to believe that there is any connection between my taking of Prozac and my heart problems, although my heart specialist (for whom I purchased and gave a copy of Ann Tracy’s book) is currently wading through the literature to see whether a link can be established. There is no family history of hypertension to the best of my knowledge, but I had left out an important medical fact from my original story.

I was briefly hospitalized for a “Heart attack” in 1995 some nine months or so after I had started taking Prozac (1994) (NB I believe that the date in my original story should read 1994 not 1995 – my fault I am afraid but the chronology is important.). Blood tests had shown that I had had a “heart attack”, but an angiogram confirmed that there had been no damage to my heart, and the tightness in my chest was put down to stress, and was dismissed as unimportant. I say “unimportant” simply because the threat (which it might have been) was dismissed, because there was no “damage” seen. My blood pressure at that stage was moderately high, but did not, at that stage require medication, as it was within the bounds of “high normal”.

In November 1998, I was referred to a sleep disorder clinic in order to sort out problems I had with sleeping, and following tests I was referred to a heart specialist as my blood pressure was high. In February 1999, I was diagnosed with Left Ventricle Hypertrophy and Hypertension following a cardiogram which identified the enlargement.

I am currently a very physically fit 46 year old and I am pleased to say well on the mend mentally. The mental scars remain and I write first to relate that recovery is slow, but it is recovery nonetheless. That four letter word “hope” is so important. Often it has been a real test of personal perseverance and a little courage. I do not believe that any of what I have achieved in the past eighteen months would have been possible without Ann Tracy’s indomitable attitude towards making us all aware of the lack of information about the long term effects of SSRIs. Again, I owe her much.

Once again my thanks to you for the life-saving work that you are doing.

Alastair Gumley

Years 2000 and Prior

This is Survivor Story number 80.
Total number of stories in current database is 96

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09/21/1999 – Prozac Found at Wedgwood Baptist Killer’s House

This just released today.

Prozac found at Wedgwood Baptist killer’s house
By Kathy Sanders
Star-Telegram Staff Writer

FORT WORTH — A doctor had prescribed the anti- depressant drug Prozac
for Larry Gene Ashbrook, but investigators are unsure whether he had
been taking it when he killed seven people and then himself in a
southwest Fort Worth church last week, police said yesterday.

http://www.star-telegram.com/news/doc/1047/1:TOPSTORY/1:TOPSTORY092199.html

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09/16/1999 – ABC News Transcript 9/15/99–SSRI Effectiveness

Thanks to one of our ICFDA Directors for obtaining the following for us:

The following message is a transcript of last night’s ABC News with
Peter Jennings: a message about the SSRIs. Tonight Peter Jennings will
discuss the “side-effects” of the SSRIs.
———————————————————————–
Peter Jennings ABC News: September 15, 1999

Peter Jennings: “Just when is the drug actually making a difference?
Antidepressants are very popular these days: sales are up 17% from just
last year. Millions and millions of prescriptions now are being
written to
battle depression and mood swings. Tonight, are these drugs really
doing
everything that people think they are? Here’s ABC’s Deborah Amos ”

Deborah Amos: “These depression fighting pills are 60 – 70% effective in
bringing relief according to the medical literature. But Thomas Moore,
who
studies drugs at George Washington University, says the numbers are
misleading”

Thomas Moore: “Millions of Americans believe that the benefits of these
drugs are much greater than they are”

Deborah Amos: “To investigate, Moore analyzed all drug company tests on
five major drugs submitted to the FDA prior to market approval: for
Paxil,
Zoloft, Effexor, Serzone and Prozac. The effectiveness of the drug was
measured against a placebo or sugar pill.”

Thomas Moore: “The effect of antidepressants drugs on depression is
only
very little different than the effect of a completely inactive placebo.”

Deborah Amos: “The highlight of Moore’s finding is the case of Prozac
with
more than $2 billion dollars in U.S. Sales. About 90% of Prozac’s
overall
effectiveness is about the same as patients taking nothing stronger
than a
sugar pill. But the label for antidepressant drugs, the prescribing
detail
for doctors, usually do not spell out the small overall differences
between
the drug and the placebos.”

Thomas Moore: “At the very least the FDA product labeling should
include a
more balanced picture of all the information they have received about
the
drug, – about all the clinical trials.”

Deborah Amos: “”The FDA says it does not put that kind of detail on the
label because it is not helpful in predicting individual outcomes. So
what
does it all mean for patients, when a placebo can have almost the same
benefits as a dug, and particularly, when a drug can have unpleasant
side-effects , —- that feeling – jumpy to <sum><sum><sum><sum><sum>

(a psychologist from the University of Conn., who has teamed up with
Thomas
Moore.)

?: “It suggests that the frontline of treatment for depression should
be
psychological rather than chemical.”

Deborah Ames: “The problem is that good therapy is expensive and not
always available. Pills are cheaper and more easily available. Deborah
Ames, ABC News, New York.”

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Prozac, Effexor, Klonopin, Serzone, Zyprexa, Neurontin, and now Celexa-and Hospitalized Seven Times.

“I sometimes am so sorry I started him on this medication journey,”

 

I have had thoughts that maybe my son’s suicide attempts were related to the Prozac and other medications that he had been taking, and now after reading correspondence from others regarding the same behaviors, I am more convinced that there was a relationship between the taking of the drug and his actions.

My son who is now 26 years old has had problems with depression probably since he was l3. He got through high school but did very poorly, and became very depressed when he graduated because he felt he had no future. At that time, I took him to see a psychiatrist who put him on Prozac, but it did not seem to help him that much. I think she tried him on Zoloft also which did not seem to help him either.

He obtained a job at a shoe store working for a very nice family who liked him and who he enjoyed working for. He stopped the drugs and seeing the psychiatrist who said my son was an enigma. He worked at the store for 5 years, but one day abruptly quit. He then worked as a security guard for approximately a year and quit that job also. He decided to go to dog grooming school, and I’ll never forget his face the day he came home from school so proud and happy that he found something to do that he liked.

He did very well at the school, but started to have panic attacks. I took him to a psychiatrist again and she put him on Prozac and Xanax. He seemed to come alive, extremely talkative, and he finally met a girl and fell deeply in love. He then seemed to have problems with his mood lowering and becoming more depressed and anxious, so the psychiatrist increased the Prozac. I noticed at this time that his behavior was worrisome. Well the girl broke up with him and he tried to kill himself.

In the hospital they changed his meds to Effexor and Klonopin, he got out of the hospital and thought the girl might come back, but when he realized two weeks later that she wasn’t, He left in the middle of the night again, and eventually checked himself into the hospital after overdosing. He was sent to another facility after this and they put him back on Prozac. He attempted suicide again by overdosing. Altogether, he was hospitalized approximately 7 different times, with four of those being for suicide attempts. The last one being a year ago. Since then he has been on Serzone, Zyprexa, Neurontin, and within the last few months Celexa was added to this. He does seem to be somewhat better, but very flat, little conversation, rarely smiling. I sometimes am so sorry I started him on this medication journey.

I wonder if he would have been better off trying to cope with his low-grade depression, and maybe just taking an anti-anxiety medication for the panic attacks. I wonder.

Years 2000 and Prior

This is Survivor Story number 54.
Total number of stories in current database is 96

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A Nine-Year Old’s Side Effects on Prozac

“I am disgusted that Prozac is so readily handed out to children.”

I am the mother of a 9 year old boy.

About four months ago, my son went through a change. He was experiencing a lot of physical growth and he was developing sexual awareness. Being OCD to a degree, my son centered on thoughts and obsessed and started acting in mildly inappropriate ways. Now, that became a real concern because it was more than thoughts but turning to actions that were being perpetuated; my husband and I became alarmed.

There was NO CAUSE for this sudden escalation except for a natural curiosity getting out of control (OCD reaction w/a boy who is emotionally immature but very intelligent &amp; spiritual).The guilt set in and no matter how we tried to help him forgive himself, he carried far too much guilt. It internalized into dropping self-esteem and finally that escalated into severe depression. Who was once a VERY happy, talkative, joyful, incredibly funny &amp; affectionate boy turned into a boy who wept daily, seldom smiled, and was becoming despondent.

We took him to a counselor, and later were referred to a psychiatrist. After an hour assessment, Dr.SHOULD HAVE KNOWN BETTER prescribed Prozac for Rob.

His reaction included: MAJOR joint/muscle pain (from the bottom of his feet to the top of his head PAIN!), lack of appetite, increased seizure symptoms (Rob has a left partial complex seizure disorder we are NOT treating with drugs but naturally and that has gone very well), abdominal pain, increased lethargy, increased OCD behavior, increase in thoughts of suicide, heart pain, vomiting, and strange feelings in his mouth/tongue. I took Rob off Prozac after only 8 days because I was so alarmed with the side effects.

After taking him off the med, I did some research and was very saddened that I’d been pushed into allowing my son to be given Prozac! I was pressured by the psychiatrist, husband (on Prozac), brother-in-law (Dr. also on Prozac), and it was approved even by the pediatrician! My taking Rob off Prozac was MY decision against all but hubby (he was worried about the escalating effects of the drug, too).It took a full 7 days for the incredible pain to go away. Rob told me it hurt even to move his fingers, walk, anything.

Well, in closing, I am disgusted that Prozac is so readily handed out to children. From what I know currently, the FDA has not even approved this drug for children, and after researching it myself, I AM WORRIED ABOUT MY HUSBAND! He has been on it for two years.

 

2/3/1999

This is Survivor Story number 30. Total number of stories in current database is 96

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Girlfriend Self-Destructed on Prozac-A Police Officer’s Story

“Please let people who are out there know that Prozac is bad medicine.”

 

Please let people who are out there know that Prozac is bad medicine. I have recently lost my girlfriend after a year because of this most marvelous chemical composition. She is a psych-tech at a local hospital in my hometown. She has worked there for almost two years, and since I have known her she has been prescribed medications like Phen-Fen and Zoloft and most recently Prozac. Yes, she probably could stand to lose a few pounds, but who couldn’t? Since being prescribed Prozac (by a staff physician) she won’t even speak to me. She feels simply that I tried to intervene.

Yet, I am a police officer of almost 10 years and could not stand by and watch someone self-destruct. It seems to me like someone needs to be policing the MD’s who are actively handing out prescriptions to our younger generation. After all they are the future, aren’t they?
Also I would like to know if it is common practice for the head of psychiatric departments to become involved in treating employees of the hospital where they work? Seems to me this would be a direct conflict of interest and would require a referral to another MD.
Please use my e-mail address for those that want to correspond. Maybe someday soon, people will wake up and see what they’re doing to themselves. Thank you for writing back, it’s always comforting to know that someone knows how you feel.

JDuffjr410@aol.com

 

10/29/1998

Years 2000 and Prior

This is Survivor Story number 32.
Total number of stories in current database is 96

424 total views, no views today

Five Weeks to Psychosis on Prozac

“It was close to 2 years before I could laugh again.”

 

My name is Amy. I started taking 20 mg. of Prozac in April, 1992. My doctor thought I was depressed due to empty nest syndrome and menopause.

I had always been a very open and trusting person, so I swallowed my first capsule without reading the insert in the bottle. I trusted my doctor. The first week I noticed I was sleeping less. I had been sleeping between 7 and 8 hours a night and now I was sleeping about 6 hours a night. But this did not concern me. I suddenly had a lot to ponder. I began ruminating on how people had done me wrong. . I first focused on my 3 cousins (whom I had not seen in years). I thought they were betraying me behind my back. To add to this worry, I began obsessing about incidents in history such as the destruction of Cambodia and Tibet by the Communists and the tragedy of the Holocaust. I sat at my kitchen table and cried for hours about this. At my part time job, I felt that the other employees were taking advantage of me. I had never felt this way before and it seemed like a revelation to me.

By the 4th week on Prozac, I was sleeping only 4 hours a night but it did not concern me because I had so many important things to think about. I would pick up a book to read and would think that there was some special message in there for me. I was sure of this when the printed matter on the page began jumping out at me. Nothing like this had ever happened to me before. I began to make a special effort to act normal around people because suddenly these people would appear to me as being unreal. I became terrified that they were unreal but I must not let them know this. During the next several weeks I became confused in my driving and would lose my sense of direction. I thought that I could not concentrate on my driving because I was so terrified of what else was happening. I never once suspected that it was the Prozac.
My husband of 28 years became concerned about me but I kept saying I’ll be better as soon as this Prozac takes effect. I told him none of my symptoms. I felt that everything wrong in the world was my problem and I must solve it. At no time in my life had I ever thought of suicide. It wasn’t as though I had ever thought of suicide and then dismissed the idea. It was just that the thought of suicide had never occurred to me. By my 9th week on Prozac I felt suicidal. I went to my doctor and told him that I was going to kill myself because I could not endure this suffering. He immediately told me to discontinue the Prozac and he gave me some sleeping medication. I thought this meant that the Prozac had not worked for me and that I was having a nervous breakdown. The next day I began having visual hallucinations. I was so terrified that I went to my doctor in an incoherent state. He put me in the hospital and I was there for 3 weeks as an inpatient. My husband visited me every night after work. We both thought that I had a nervous breakdown. No doctor told us differently. I was given Thorazine and I began to sleep again. Then my health insurance ran out and I came back home. When I left the hospital, I was told to see a psychologist once a week. The psychologist and I discussed my childhood. One day, three months later, my husband said Do you think the Prozac could have contributed to your breakdown .No , I said, Prozac is a drug that helps mental disturbances. It would not cause mental disturbance.

My husband found the insert to my bottle of Prozac. We began to read it. We saw that hallucinations, depersonalization, paranoia and confusion were all listed as adverse reactions. I still could not believe it so I sent for my hospital record. I was amazed to see that on the fourth day of my hospitalization the physician had written Patient had psychotic reaction to Prozac. These symptoms started after use. We investigated this matter but were never given a satisfactory answer for why the doctors kept this a secret. The saddest part of this story is that it took so long for me to completely recover. It was close to 2 years before I could laugh again. It was almost 4 years before the idea of forgiveness even began to stir in my soul. Now, in my 6th year, I am completely recovered and enjoying life again, but I will never forget this trip through hell.

My husband, children and I are now dedicated to warning others about the dangers of Prozac.

 

10/29/1998

Years 2000 and Prior

This is Survivor Story number 34.
Total number of stories in current database is 96

632 total views, no views today

9/1/1998 • Prenatal Exposure to Fluoxetine (Prozac) Produces Site-Specific and Age-Dependent Alterations in Brain Serotonin Transporters in Rat Progeny: Evidence from Autoradiographic Studies

9/1/1998 • Prenatal Exposure to Fluoxetine (Prozac) Produces Site-Specific and Age-Dependent Alterations in Brain Serotonin Transporters in Rat Progeny: Evidence from Autoradiographic Studies

Theresa M. Cabrera-Vera2 and George Battaglia
Department of Pharmacology and Experimental Therapeutics, Loyola University of Chicago, Stritch School of Medicine, Maywood, Illinois

Pharmacology; Vol. 286 Issue 3, 1474-1481, September 1998

The age-dependent and site-specific alterations in the density of 5-HT transporters suggests that either 5-HT innervation and/or 5-HT neuron function in various forebrain regions may be altered by prenatal exposure to fluoxetine.

Prenatal Exposure to Fluoxetine (Prozac) Produces Site-Specific and Age-Dependent Alterations in Brain Serotonin Transporters in Rat Progeny: Evidence from Autoradiographic Studies

http://jpet.aspetjournals.org/cgi/content/full/286/3/1474

Theresa M. Cabrera-Vera2 and George Battaglia
Department of Pharmacology and Experimental Therapeutics, Loyola University of Chicago, Stritch School of Medicine, Maywood, Illinois

Pharmacology; Vol. 286 Issue 3, 1474-1481, September 1998

The age-dependent and site-specific alterations in the density of 5-HT transporters suggests that either 5-HT innervation and/or 5-HT neuron function in various forebrain regions may be altered by prenatal exposure to fluoxetine.

The present study provides the first autoradiographic evidence of age-dependent regional changes in the density of serotonin (5-HT) transporters in offspring following prenatal exposure to fluoxetine. Pregnant rats received either saline or fluoxetine (10 mg/kg, s.c.) daily from gestational day 13 through 20. The density of [3H]citalopram-labeled 5-HT transporters was determined in forebrain regions and in midbrain raphe nuclei of prepubescent and adult male offspring. Brain regions representing integral components of the limbic system were particularly sensitive to the prenatal treatment. For example, prenatal fluoxetine exposure significantly altered the density of 5-HT transporters in subregions of the hypothalamus (dorsomedial nucleus, 21%; lateral hypothalamus, +21%), hippocampus (CA2, +47%; CA3, +38%), and amygdala (basolateral nucleus, +32%; medial nucleus, +44%) in prepubescent offspring. However, 5-HT transporter density in the dorsal and median raphe was unaltered in this same group of offspring. In adult offspring, 5-HT transporter densities, in all brain regions examined, were not significantly altered by prenatal exposure to fluoxetine. The present study also identifies significant age-related differences in 5-HT transporter densities between prepubescent and adult control offspring. For example, in adult control offspring, densities of 5-HT transporters were significantly greater in the cingulate cortex (+33%), basolateral amygdala (+58%), and CA1 area of the hippocampus (+78%); but significantly lower in the temporal cortex (65%) and median raphe (25%).

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Cushing’s Syndrome on Prozac–A Nurse’s Story

” (I) thought it was saving my life, while all the time it was insidiously and slowly killing me.”

 

I started having bad reactions in Oct. ’96. I found Prozac to be causing joint and muscle pain itself. I also became concerned that I was developing signs of Cushing’s Syndrome. I was very pro-Prozac until last October and wouldn’t have listened to anything said against it until I got problems (thought it was saving my life, while all the time it was insidiously and slowly killing me!) When I first heard about your book (Prozac: Panacea or Pandora?) on the Internet I was interested but quite skeptical. However, since reading it and having suffered so many problems with Prozac, I have come to the conclusion that the book is brilliant, and a life-line as far as I am concerned. I tried to fault the research and reasoning, but could not and still can’t. I would like to extend my thanks to you for your heroic stance on this enormously important issue. I have tremendous respect and admiration for your hard work, determination and courage in pursuing this subject so vigorously, against so much powerful opposition for the benefit of people like me. Your integrity puts many, if not most doctors and psychiatrists to shame. It is reassuring to find that there are a few people in the world who are prepared to fight for the truth for the benefit of mankind.

A.S., A British Nurse

 

9/1/1997

Years 2000 and Prior

This is Survivor Story number 37.
Total number of stories in current database is 96

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