STUDY: Paxil Offers Little Benefit Over Placebo in Depression or Anxiety

Paxil pill



A new study has been published in PLOS demonstrating that Paxil, which they point out works like most all other antidepressants indicating similar results can be expected for all other antidepressants, is of little more benefit than a placebo. See the information in my comment to demonstrate the dangers of antidepressants and to support your arguments against the use of these drugs. Find the link to the article on the study below and my comments to one comment disputing the reputation of the PLOS journal and to the study results below.


First of all there is NOTHING of questionable repute when it comes to PLOS. It is well respected. Most likely the only ones questioning their repute after this study are those connected to the $11 Billion (Plus) income coming in from antidepressants. 🙂

No one should find the results of this study surprising at all because it is only supporting old news. I believe it was back in 2008 the news broke that studies kept hidden by the antidepressant manufacturers for 20 years, even kept hidden from the FDA, demonstrated there was no more benefit from antidepressants than placebo. Google it.

So no benefit, yet if you read the side effects it is clear to see that the risk to benefit ratio of these drugs is “down the toilet”!

The drugs carry warnings of both suicidal and homicidal ideation (that is constant compulsive thoughts of killing oneself or others along with the same constant compulsive thoughts of various ways to kill).

Antidepressants are also found in 86% of the diagnosed cases of REM Sleep Disorder where patients act out nightmares in a sleep state and which is also known to include both murder and suicide.

All this negative potential when a placebo would offer as much in the way of benefit?! Seriously?

And suicidal and homicidal compulsions are only the tip of the antidepressant iceberg! You also have the 7 times greater chance of breast cancer with Paxil which is now being touted for menopause under the new name Brisdelle and specifically for women with a greater risk of breast cancer!

Then there is the three to four times greater rate of Autism for the children born to moms who take antidepressants, not to mention all the babies born with holes in their hearts or transposed arteries – both requiring open heart surgeries at birth and a lifetime of medical issues after..

And to top that off the hypothesis behind the drugs is backwards. Serotonin was never low in depression! What was low in depression, anxiety, suicide, psychosis, mania, impulsive murder or suicide, cravings for alcohol, etc was serotonin metabolism – the exact thing antidepressants are designed to inhibit! Which means the drugs should cause all of the above reactions. (See my 2004 testimony before the FDA Advisory Committee for additional data on that issue.) Just read a package insert for warnings of most all of the above as possible “side effects.”

Add to all that the fact that antidepressants produce horrible and very dangerous withdrawal for many unless they know enough to go down EXTREMELY slowly taking months or years (depending on how long they have been on the drugs) to wean off only a granule or two at a time in order to do so safely and successfully, Most patients and their doctors attempt to wean much too rapidly producing rebound depression from the withdrawal thus causing the patient to end up back on the drugs again. This is the reason people stay on antidepressants for so long – THEY DO NOT KNOW HOW TO GET OFF SAFELY!!!

Clearly there is no benefit that justifies any of the risks!


Ann Blake Tracy, Executive Director,
International Coalition for Drug Awareness &
Author: ”Prozac: Panacea or Pandora? – Our Serotonin Nightmare – The Complete Truth of the Full Impact of Antidepressants Upon Us & Our World” & Withdrawal CD “Help! I Can’t Get Off My Antidepressant!”

WITHDRAWAL HELP: You can find the hour and a half long CD on safe and effective withdrawal helps here: And if you need additional consultations with Ann Blake-Tracy, you can book one at or sign up for one of the memberships for the International Coalition for Drug Awareness which includes free consultations as one of the benefits of that particular membership plan.

WITHDRAWAL WARNING: In sharing this information about adverse reactions to antidepressants I always recommend that you also give reference to my CD on safe withdrawal, Help! I Can’t Get Off My Antidepressant!, so that we do not have more people dropping off these drugs too quickly – a move which I have warned from the beginning can be even more dangerous than staying on the drugs!